Molecular anatomy resources for postembryonic zebrafish
Molecular anatomy resources for postembryonic zebrafish
批准号:
10170587
负责人:
DAVID M PARICHY
金额:
$8.08万
依托单位:
依托单位国家:
美国
项目类别:
财政年份:
2021
资助国家:
美国
项目状态:
已结题
起止时间:
2021-05-10 至 2023-04-30
关键词:
AdultAnatomyAnimal ModelAtlasesBiomedical ResearchCellsCommunitiesCongenital AbnormalityDataDatabasesDevelopmentDiseaseEmbryoEventFishesHealthHumanIn Situ HybridizationInvestigationLaboratoriesLarvaLocationMessenger RNAMolecularMorphogenesisNatural regenerationOrganOrganogenesisPatternPhenotypeProcessResearchResearch PersonnelResourcesSpatial DistributionSystemTissuesWorkZebrafishcandidate markercell typediagnostic biomarkerhistological imagehuman diseaseimaging approachmolecular markermutantregeneration potentialsingle-cell RNA sequencingtranscriptomicszebrafish development
中文摘要
点击翻译按钮获取中文摘要
英文摘要
PROJECT SUMMARY
The zebrafish is a widely used biomedical model organism and has been studied extensively at early stages.
Current research efforts focus increasingly on later stages that are relevant to understanding fundamental as-
pects of vertebrate development as well as human disease, birth defects and regenerative potential. This
project will provide a resource to facilitate such studies by identifying molecular markers for specific cell types
present at late stages, and mapping these markers and the cells they represent within the developing anatomy
of the larval fish. Candidate markers and cell types will be identified using unbiased single cell transcriptomic
approaches, and anatomical mapping will be accomplished using histological and imaging approaches, all of
which are routine for this laboratory. These resources will enable efforts by the community of investigators us-
ing zebrafish for biomedical research, and will provide opportunities to further exploit this system for under-
standing and promoting human health.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
Mechanisms of signal transmission in vertebrate skin appendage development.
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批准号:10414871
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项目类别:
-
资助金额:$35.17万
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财政年份:2021
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负责人:DAVID M PARICHY
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依托单位:
Molecular anatomy resources for postembryonic zebrafish
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批准号:10402832
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项目类别:
-
资助金额:$8.08万
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财政年份:2021
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负责人:DAVID M PARICHY
-
依托单位:
Mechanisms of signal transmission in vertebrate skin appendage development.
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批准号:10612893
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项目类别:
-
资助金额:$35.53万
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财政年份:2021
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负责人:DAVID M PARICHY
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依托单位:
Mechanisms of signal transmission in vertebrate skin appendage development.
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批准号:10096475
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项目类别:
-
资助金额:$35.53万
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财政年份:2021
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负责人:DAVID M PARICHY
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依托单位:
Developmental origins and homeostatic mechanisms underlying adult phenotypes: multispectral sorting of pigment cells from zebrafish and non-traditional model species
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批准号:10799015
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项目类别:
-
资助金额:$25.0万
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财政年份:2017
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负责人:DAVID M PARICHY
-
依托单位:
DEVELOPMENTAL ORIGINS AND HOMEOSTATIC MECHANISMS UNDERLYING ADULT PHENOTYPES
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批准号:9275178
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项目类别:
-
资助金额:$1.04万
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财政年份:2017
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负责人:DAVID M PARICHY
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依托单位:
Developmental origins and homeostatic mechanisms underlying adult phenotypes
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批准号:10615882
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项目类别:
-
资助金额:$58.92万
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财政年份:2017
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负责人:DAVID M PARICHY
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依托单位:
DIVERSITY SUPPLEMENT TO DEVELOPMENTAL ORIGINS AND HOMEOSTATIC MECHANISMS UNDERLYING ADULT PHENOTYPES
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批准号:10622666
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项目类别:
-
资助金额:$5.38万
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财政年份:2017
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负责人:DAVID M PARICHY
-
依托单位:
Developmental origins and homeostatic mechanisms underlying adult phenotypes
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批准号:10406462
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项目类别:
-
资助金额:$58.92万
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财政年份:2017
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负责人:DAVID M PARICHY
-
依托单位:
Developmental origins and homeostatic mechanisms underlying adult phenotypes
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批准号:10725034
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项目类别:
-
资助金额:$8.07万
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财政年份:2017
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负责人:DAVID M PARICHY
-
依托单位:
DEVELOPMENTAL ORIGINS AND HOMEOSTATIC MECHANISMS UNDERLYING ADULT PHENOTYPES
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批准号:9615510
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项目类别:
-
资助金额:$47.22万
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财政年份:2017
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负责人:DAVID M PARICHY
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依托单位:
PIGMENTARY MODEL FOR THYROID HORMONE ACTIONS ON STEM CELL LINEAGES
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批准号:8740681
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项目类别:
-
资助金额:$29.41万
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财政年份:2014
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负责人:DAVID M PARICHY
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依托单位:
PIGMENTARY MODEL FOR THYROID HORMONE ACTIONS ON STEM CELL LINEAGES
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批准号:9615670
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项目类别:
-
资助金额:$8.9万
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财政年份:2014
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负责人:DAVID M PARICHY
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依托单位:
PIGMENTARY MODEL FOR THYROID HORMONE ACTIONS ON STEM CELL LINEAGES
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批准号:8914645
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项目类别:
-
资助金额:$32.04万
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财政年份:2014
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负责人:DAVID M PARICHY
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依托单位:
Genetic control of post-embryonic developmental progression in zebrafish
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批准号:8427198
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项目类别:
-
资助金额:$7.73万
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财政年份:2012
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负责人:DAVID M PARICHY
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依托单位:
Melanocyte boundary interactions in development and neoplasia
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批准号:8725517
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项目类别:
-
资助金额:$29.09万
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财政年份:2011
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负责人:DAVID M PARICHY
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依托单位:
Melanocyte boundary interactions in development and neoplasia
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批准号:8075202
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项目类别:
-
资助金额:$38.81万
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财政年份:2011
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负责人:DAVID M PARICHY
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依托单位:
Melanocyte boundary interactions in development and neoplasia
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批准号:8535273
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项目类别:
-
资助金额:$28.67万
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财政年份:2011
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负责人:DAVID M PARICHY
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依托单位:
Melanocyte boundary interactions in development and neoplasia
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批准号:8333349
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项目类别:
-
资助金额:$30.31万
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财政年份:2011
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负责人:DAVID M PARICHY
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依托单位:
EQUIPMENT SUPPLEMENT REQUEST: Cellular Interactions Underlying Establishment and Implementation of Zebrafish Adult Pigment Pattern
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批准号:9273884
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项目类别:
-
资助金额:$13.25万
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财政年份:2011
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负责人:DAVID M PARICHY
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依托单位:
海外基金