Penn State University's Translational Center for Child Maltreatment Studies TCCMS

项目总结/摘要 尽管有关当前COVID-19大流行的新数据表明，儿童和 青少年被诊断为严重COVID-19感染的风险较低，严重不良反应 据报告，这一年龄组的儿童受到了包括死亡在内的影响。此外，关注儿童 和青少年轻度COVID-19感染继续传播感染仍然存在。尽管是 年轻人不太可能被诊断为COVID-19病例，但他们的生活受到了 2019冠状病毒病疫情在许多方面，包括由于日常生活和教育中断 经验，减少与同龄人和家庭的社会接触，并可能增加接触 不安全的家庭环境，不堪重负的照顾者，家庭暴力事件，以及， 可能是虐待儿童的事件这表明有虐待儿童史的年轻人 可能特别容易受到COVID-19大流行的直接和间接影响， 他们很可能来自已经经历多种困难的家庭。这影响了一个很大的 青年人数;超过三分之一的美国青年被调查虐待儿童（CM）之前， 18岁拟议的项目将建立在目前正在进行的儿童健康研究（CHS; HD089922，PI：Noll，Co-I：Schreier），其中775名8 - 13岁的青少年最近 正在招募225名没有CM病史的青少年进行CM调查， 前瞻性地跟踪。利用这一独特的、特征非常鲜明的群体， 我们将增加已经收集的生物心理社会数据，以研究脆弱性， 这些年轻人对COVID-19感染的抵御能力，以及 目前正在经历的照顾者在研究中可能会蔓延到影响青年福祉 在这场大流行病期间和之后。我们将研究是否有广泛的生理， 例如，在一个实施例中，内分泌，免疫和代谢，以及心理社会和人口统计学特征， 青年与已知的COVID-19感染有关，或与没有已知的感染有关， 与已知感染者密切接触的情况。此外，我们将 调查增加照顾者压力对现有青年健康可能恶化的影响 问题，压力的生理标志，以及虐待儿童的新事件。因此， 揭示了一些社会上最脆弱的个人当前和未来的经历， 由此产生的数据有可能为未来的干预提供一个强有力的起点 支持这些年轻人的计划，这些年轻人正在并将在2010年之后过渡到成年人。 2019冠状病毒病疫情。重要的是，这一知识还将用于对以下问题作出知情反应： 未来可能发生的大流行病，可能对个人的日常生活产生类似的影响。

PROJECT SUMMARY / ABSTRACT Although emerging data regarding the current COVID-19 pandemic suggest that children and adolescents have a lower risk of being diagnosed with severe COVID-19 infections, serious adverse effects, including death, have been reported in this age group. Additionally, concerns that children and adolescents with mild COVID-19 infections continue to spread infections remain. Despite being less likely to be diagnosed with cases of COVID-19, youth's lives are profoundly impacted by the COVID-19 pandemic in numerous ways, including due to disrupted daily routines and educational experiences, reduced social contacts with peers and families, and, potentially, increased exposures to unsafe home environments, overwhelmed caregivers, incidents of domestic violence, and, possibly, incidents of child maltreatment. This highlights that youth with a history of child maltreatment may be particularly vulnerable to the direct and indirect effects of the COVID-19 pandemic seeing as they are likely to come from families already experiencing multiple hardships. This impacts a large number of youth; over one third of U.S. youth are investigated for child maltreatment (CM) before the age of 18. The proposed project will build on the currently ongoing Child Health Study (CHS; HD089922, PI: Noll, Co-I: Schreier), as part of which 775 youth aged 8-13 years who were recently investigated for CM as well as 225 comparison youth without a history of CM are being recruited and followed prospectively. Taking advantage of this unique and exceptionally well-characterized cohort, we will augment the biopsychosocial data already being collected to examine vulnerability and resilience towards COVID-19 infections among these youth, as well as how the additional stress that is currently being experienced by caregivers in the study may spill over to impact youth well-being throughout and following this pandemic. We will examine whether a broad range of physiological, e.g., endocrine, immune, and metabolic, as well as psychosocial, and demographic characteristics of youth are associated with known infections of COVID-19 or with an absence of known infections in the context of having been in close contact with individuals with known infections. Additionally, we will investigate the influence of added caregiver stress on possible exacerbations of existing youth health problems, physiological markers of stress, and new incidents of child maltreatment. Thus, by shedding light on the current and future experiences of some of society's most vulnerable individuals, the resulting data have the potential to provide a powerful jumping-off point for future intervention programs to support these youth who are and will be transitioning into adulthood in the wake of the COVID-19 pandemic. Importantly, this knowledge will also carry forward into informing responses to possible future pandemics which may have similar effects on the everyday lives of individuals.