SouthEast Enrollment Center (SEEC)

过去十年的一些发展正在推动大胆的新项目，这些项目可以实现这一承诺 精准的或个性化的医学。虽然DNA测序成本继续快速下降，但同样重要的是电子健康记录(EHR)的广泛采用，允许低成本、高度安全地交换来自个人的大量纵向健康数据。此外，消费者越来越多地采用移动和个人技术，提供了以前所未有的规模将基因组和健康数据与暴露、行为和其他环境健康数据联系起来的机会。我们必须确保所有人都能享受到这些进步的好处。我们所有人研究计划(AoURP)成功的关键将是按比例纳入不同的群体。 这是“东南招生中心”(SEEC)联合体的一大优势。SEEC将从佛罗里达州和佐治亚州招募93,000名正式参与者加入AoURP，其中包括大约30%的西班牙裔/拉丁裔志愿者和30%的黑人/非裔美国人志愿者。重要的是，一半的拉美裔美国人将来自加勒比地区(例如古巴、波多黎各和多米尼加共和国)，另一半将来自南美洲和中美洲。我们的黑人样本将包括来自海地和讲英语的加勒比海岛屿的参与者。该联盟将由佛罗里达州和佐治亚州的四个领先的学术健康中心带头。每个成员在建立基因组队列、招募少数族裔参与临床研究、形成社区参与伙伴关系以及在大型网络中共享医疗记录(例如，所有成员都参与PCORnet)方面都有相当大的记录。

A number of developments over the last decade are promoting bold new projects that can enable the promise of precision or personalized medicine. While DNA sequencing costs continue to drop rapidly, equally important has been the widespread adoption of electronic health records (EHR) allowing for the low cost, highly secure exchange of large amounts of longitudinal health data from individuals. In addition, the increasing consumer adoption of mobile and personal technologies offers the opportunity to link genomic and health data with exposure, behavioral, and other environmental health data on a scale not previously possible. We must ensure that the benefits of these advances are accessible to all. Key to the success of the All of Us Research Program (AoURP) will be the proportional inclusion of diverse groups. This is a major strength of the “SouthEast Enrollment Center” (SEEC) consortium. SEEC will recruit 93,000 full participants from Florida and Georgia into AoURP, including approximately 30% Hispanic/Latino and 30% Black/African American volunteers. Importantly, half of the Hispanics will come from the Caribbean (e.g. Cuba, Puerto Rico and the Dominican Republic) and the other half from South and Central America. Our sample of Blacks will include participants from Haiti and English-speaking Caribbean islands. The Consortium will be spearheaded by four leading academic health centers in Florida and Georgia. Each member brings a considerable track record of establishing genomic cohorts, recruiting minorities into clinical research, forming community engagement partnerships, and sharing medical records across large networks (e.g. all participate in PCORnet).