Miami Clinical and Translational Science Institute

迈阿密临床与转化科学研究所

• 批准号: 10440534
• 负责人: Olveen Carrasquillo
• 金额: $ 359.15万
• 依托单位: UNIVERSITY OF MIAMI SCHOOL OF MEDICINE
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-06-28 至 2023-10-17
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10440534
• 关键词: Achievement; Adopted; Affect; Area; Award; Back; Clinic; Clinical Research; Clinical Sciences; Collaborations; Communities; Community Health Aides; Computational Science; Consultations; Data; Development; Diabetes Mellitus; Disadvantaged; Discipline; Ensure; Florida; Funding; HIV; Health; Health Benefit; Health Personnel; Health Sciences; Human; Individual; Informatics; Innovation Corps; Institutes; Institution; Intervention; Joints; Knowledge; Language; Laws; Leadership; Longevity; Mentors; Mentorship; Methods; Minority Groups; Mission; National Center for Advancing Translational Sciences; National Institute on Minority Health and Health Disparities; Operations Research; Pathogenesis; Patients; Phase; Play; Policies; Population; Population Heterogeneity; Positioning Attribute; Process; Reporting; Research; Research Personnel; Research Technics; Research Training; Role; Rural; Science; Secure; Site; Strategic Planning; Stroke; Structure; Substance abuse problem; Supercomputing; Technology; Training; Training and Education; Transcend; Translational Research; Trust; Underrepresented Minority; Underserved Population; United States; United States National Institutes of Health; Universities; Urban Health; Voice; Work; career development; clinical data warehouse; cultural health; cyber infrastructure; data lake; data warehouse; ethnic minority; health disparity; improved; innovation; literacy; minority communities; minority health disparity; multidisciplinary; programs; racial and ethnic; research facility; rural healthcare; success; tool; treatment response; working group

Funded as a CTSA in 2012, the Miami Clinical and Translational Science Institute (CTSI) serves as Miami’s academic Hub for interdisciplinary clinical and translational (C/T) research, innovation, and training. Our mission is to accelerate scientific discoveries into interventions that improve health, with a focus on minority populations. The cornerstone of our successful strategy is the sustained support of dynamic partnerships in culturalizing health science—adapting our research to be culturally congruent with diverse stake-holder communities with whom we partner in C/T research, research training, and, importantly, research translation. In a region that is over 88% racial/ethnic minorities, we have modified research techniques to better suit the culture, language, literacy, and norms of groups with whom we work and have fundamentally changed research tools and methods to more precisely capture cultural complexity that greatly affects all aspects of C/T research. We have invested heavily in new research facilities and IT/informatics, including a clinical data warehouse and our Center for Computational Science – one of the largest centralized academic cyber infrastructures in the United States. To develop our workforce, we completely revamped our Clinical Research Professional framework and initiated extensive mentorship programs for all research stakeholders, including Community Health Workers. To lend community voice to research and expand our Hub beyond our traditional walls, our CTSI helped create the OneFlorida Clinical Research Consortium with a data trust and statewide network of urban and rural health care providers and nearly 11M diverse patients across Florida. And as an innovator in the CTSA Network, we participated in shared leadership of consortium-wide activities including the Enhancing Clinical Research Professionals’ Training & Qualifications Supplement Award, and as a pilot site for the i-Corps™ at NCATS program. Well-positioned for CTSA 2.0, our Overall Specific Aims are to: (1) Provide education, training, career development, and mentoring to enhance research excellence in our C/T research workforce; (2) Advance C/T research through partnerships and innovative methods of engaging diverse stakeholders; (3) Integrate disciplines and translational phases to accelerate discovery that benefits the health of diverse populations and individuals across the lifespan; (4) Ensure research processes expedite the conduct of research and add to our understanding of the principles of advancing translational science; (5) Manage a dynamic program of informatics and computational functionality, training, consultation, and development for researchers to effectively use technology to advance their research.

迈阿密临床和转化科学研究所（CTSI）于2012年作为CTSA获得资助，是迈阿密的 跨学科临床和转化（C/T）研究，创新和培训的学术中心。我们的使命 加速科学发现转化为改善健康的干预措施，重点是少数群体。 我们成功战略的基石是持续支持充满活力的伙伴关系， 健康科学-调整我们的研究，使其在文化上与不同的社区保持一致， 我们在C/T研究、研究培训以及重要的研究翻译方面与他们合作。的区域中 超过88%的种族/少数民族，我们已经修改了研究技术，以更好地适应文化，语言， 识字率，以及与我们合作的群体的规范，并从根本上改变了研究工具和方法 更准确地捕捉文化的复杂性，极大地影响了C/T研究的各个方面。我们已经投资 在新的研究设施和IT/信息学，包括临床数据仓库和我们的中心， 计算科学-美国最大的集中式学术网络基础设施之一。到 发展我们的劳动力，我们完全改造了我们的临床研究专业框架，并启动了 为所有研究利益相关者提供广泛的指导计划，包括社区卫生工作者。放贷 社区的声音，研究和扩大我们的中心超越我们的传统墙壁，我们的CTSI帮助创建 OneFlorida临床研究联盟拥有数据信任和全州城乡医疗保健网络 供应商和佛罗里达近1100万不同的患者。作为CTSA网络的创新者，我们 参与了联盟范围内活动的共同领导，包括加强临床研究 专业人员培训和资格补充奖，并作为NCATS i-Corps™的试点 程序. CTSA 2.0定位良好，我们的总体具体目标是：（1）提供教育，培训，职业生涯 发展和指导，以提高我们C/T研究队伍的研究卓越性;（2）先进的C/T 通过伙伴关系和创新方法进行研究，使不同的利益攸关方参与进来;（3）整合 学科和转化阶段，以加速有利于不同人群健康的发现， （4）确保研究过程加快研究的进行，并增加我们的研究成果。 理解推进转化科学的原则;（5）管理信息学的动态计划 和计算功能，培训，咨询和发展，为研究人员有效地使用 技术来推进他们的研究。

项目成果

The Effect of Changing Fellowship Interview Format on Candidate Ranking Variabilities: The COVID-19 Experience.

• DOI: 10.1155/2022/7402079
• 发表时间: 2022
• 期刊: Journal of ophthalmology
• 影响因子: 1.9

Therapeutic hypothermia reduces cortical inflammation associated with utah array implants.

治疗性体温过低可减少与犹他州阵列植入物相关的皮质炎症。

• DOI: 10.1088/1741-2552/ab85d2
• 发表时间: 2020-04-29
• 期刊: Journal of neural engineering
• 影响因子: 4
• 作者: Dugan EA;Bennett C;Tamames I;Dietrich WD;King CS;Prasad A;Rajguru SM
• 通讯作者: Rajguru SM

Predictors of cancer rehabilitation medicine referral and utilization based on the Moving Through Cancer physical activity screening assessment.

• DOI: 10.1007/s00520-023-07679-6
• 发表时间: 2023-03-16
• 期刊: Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer

Histopathology and Ultrastructural Findings of Fatal COVID-19 Infections on Testis.

• DOI: 10.5534/wjmh.200170
• 发表时间: 2021-01
• 期刊: The world journal of men's health
• 作者: Achua JK;Chu KY;Ibrahim E;Khodamoradi K;Delma KS;Iakymenko OA;Kryvenko ON;Arora H;Ramasamy R
• 通讯作者: Ramasamy R

TNFR2 Signaling Regulates the Immunomodulatory Function of Oligodendrocyte Precursor Cells.

• DOI: 10.3390/cells10071785
• 发表时间: 2021-07-15
• 期刊: Cells
• 影响因子: 6
• 作者: Desu HL;Illiano P;Choi JS;Ascona MC;Gao H;Lee JK;Brambilla R
• 通讯作者: Brambilla R