Precision Clinical Trial Recruitment to Promote Cancer Health Equity Across Florida

精准临床试验招募促进佛罗里达州癌症健康公平

基本信息

  • 批准号:
    11002204
  • 负责人:
  • 金额:
    $ 68.29万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2022
  • 资助国家:
    美国
  • 起止时间:
    2022-09-09 至 2027-08-31
  • 项目状态:
    未结题

项目摘要

PROJECT SUMMARY Racial and ethnic minorities represent the fastest growing segment of the United States adult population, yet they remain significantly underrepresented in cancer clinical trials (CCTs). Low trust in clinical research and recruitment approaches that fail to address multilevel barriers to CCT participation are key reasons for minority population underrepresentation. Community health educators (CHEs) improve trust in research among underrepresented populations, yet relying on exclusively on CHE availability can limit intervention reach. Virtual CHEs (vCHEs) improve scalability by extending CHE capabilities and capitalizing on remote recruitment techniques. The purpose of the current project is to increase referral of diverse participants to NCI-supported clinical trials via a culturally responsive, multi-level intervention that utilizes vCHEs to reach diverse populations. We will consolidate existing referral channels within the ALEX Research Portal. ALEX offers a custom experience for clinicians, CHEs, and patients to facilitate CCT referrals. Clinicians can utilize the portal to refer to CCTs; CHEs can use the portal to create an avatar that can provide introductory information to patients and schedule video-conference follow-ups; patients, families, and community members can use the portal to easily navigate to key information and make self- and other-referrals. The ability to streamline information to patients and CCT referrals to study coordinators is expected to improve the overall referral to CCTs. The ALEX Research Portal utilizes the adaptive virtual human technology developed at the University of Florida that provides users with culturally and linguistically tailored CCT information. The ALEX Research Portal will be developed and launched across three distinct geographic areas of Florida (Gainesville, Jacksonville, and Miami). This unique collaborative opportunity will provide access to participants representative of the racial and ethnic diversity of the state as well as cancer centers conducting CCTs associated with national networks (ETCTN, NCTN). Guided by the Interactive Systems Framework for dissemination and implementation, our goal is to increase referrals to CCTs by optimizing the ALEX Research Portal for broad use. The outcome will be an evidence-based intervention that can be widely disseminated to quickly increase the referral of diverse patients to CCTs. This project will be conducted in three phases: (Phase I) establish a baseline of referrals and accrual of diverse participants to CCTs across multiple Florida Center Centers, (Phase 2) adapt and pilot the ALEX Research Portal using a randomized controlled clinical trial, and (Phase 3) scale the intervention by dissemination via the OneFlorida network. The proposed study will result in an empirically-tested vCHE Research Portal for increasing trust in CCTs among diverse populations that can easily be adapted and disseminated across the state to overcome challenges associated with recruiting diverse participants to CCTs.
项目总结

项目成果

期刊论文数量(0)
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Olveen Carrasquillo其他文献

Olveen Carrasquillo的其他文献

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{{ truncateString('Olveen Carrasquillo', 18)}}的其他基金

Miami Clinical and Translational Science Institute
迈阿密临床与转化科学研究所
  • 批准号:
    10708431
  • 财政年份:
    2023
  • 资助金额:
    $ 68.29万
  • 项目类别:
Cardiovascular Research Empowerment Workforce
心血管研究赋权劳动力
  • 批准号:
    10680765
  • 财政年份:
    2023
  • 资助金额:
    $ 68.29万
  • 项目类别:
Precision Clinical Trial Recruitment to Promote Cancer Health Equity Across Florida
精准临床试验招募促进佛罗里达州癌症健康公平
  • 批准号:
    10538749
  • 财政年份:
    2022
  • 资助金额:
    $ 68.29万
  • 项目类别:
Community Engagement Core
社区参与核心
  • 批准号:
    10494164
  • 财政年份:
    2021
  • 资助金额:
    $ 68.29万
  • 项目类别:
Community Engagement Core
社区参与核心
  • 批准号:
    10657763
  • 财政年份:
    2021
  • 资助金额:
    $ 68.29万
  • 项目类别:
Community Engagement Core
社区参与核心
  • 批准号:
    10437312
  • 财政年份:
    2021
  • 资助金额:
    $ 68.29万
  • 项目类别:
Novel, High-Impact Studies Evaluating Health System and Healthcare Professional Responsiveness to COVID-19
评估卫生系统和医疗保健专业人员对 COVID-19 反应的新颖、高影响力研究
  • 批准号:
    10193144
  • 财政年份:
    2020
  • 资助金额:
    $ 68.29万
  • 项目类别:
Novel, High-Impact Studies Evaluating Health System and Healthcare Professional Responsiveness to COVID-19
评估卫生系统和医疗保健专业人员对 COVID-19 反应的新颖、高影响力研究
  • 批准号:
    10310504
  • 财政年份:
    2020
  • 资助金额:
    $ 68.29万
  • 项目类别:
Behavioral and Community-based Shared Resources
行为和社区共享资源
  • 批准号:
    10190859
  • 财政年份:
    2019
  • 资助金额:
    $ 68.29万
  • 项目类别:
Behavioral and Community-based Shared Resources
行为和社区共享资源
  • 批准号:
    10670840
  • 财政年份:
    2019
  • 资助金额:
    $ 68.29万
  • 项目类别:

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Molecular Interaction Reconstruction of Rheumatoid Arthritis Therapies Using Clinical Data
  • 批准号:
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  • 批准年份:
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精准临床试验招募促进佛罗里达州癌症健康公平
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    10538749
  • 财政年份:
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A vascularized patient-derived iPSC liver acinus microphysiology system as an innovative precision medicine platform for optimizing clinical trial design for nonalcoholic fatty liver disease
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