Chemistry of Life Processes Predoctoral Training Program

项目摘要/摘要 拟议的“生命过程化学(CLP)博士前培训计划”的使命是教育 下一代跨学科科学家将能够扩展和整合 生命科学和化学对复杂科学问题的看法和方法 生物医学研究。在治疗疾病中遇到的跨越时间和长度的复杂问题 需要广泛的技能以及驾驭拥有各种不同技能的团队的能力 促进新疗法和诊断方法发现的专业知识。为了向紧迫的公众发表讲话 21世纪的健康需求，下一代研究人员必须能够在 一种跨越化学和生物的共同语言。 中电博士前培训计划的续签将通过向西北大学提供 研究生有机会将化学和生命科学的研究生课程整合到一个学位 超过了西北大学目前正在进行的任何培训项目。它的深度和广度 课程要求、新颖的身临其境的跨学科实验室体验以及独特的 CLP计划，加上强大的共享培训环境，使该计划有别于其他计划 西北大学生物医学研究培训计划。该计划建立在高度协作、 49名在药物领域具有广泛专业知识的导师的跨学科生物医学研究计划 发展、合成生物学和潜在的治疗干预分子靶点。 此应用程序请求在五年内提供总计40个培训时段的支持，以创建充满活力的 具有共同身份的同龄人有足够的数量来支持学生主导的项目活动。实习生是 从第二年秋季开始接受资助，并在整个 第二年和第三年的研究生教育。在01-05学年，每年将有8名学生获得资助。十 额外的学生将获得为期一年的大学奖学金。 西北大学生命过程化学研究所是拟议中的培训计划的行政中心， 为中电学员提供强大的跨学科研究和培训生态系统，其中包括 高度协作的教职员工团队，跨越化学和生命科学，独特的共享资源， 为药物发现和开发提供无缝管道，提供具有以下专业知识的使能基础设施 制定和管理教育和培训计划，在翻译方面有丰富的经验 有益于社会的发现，以及推动跨学科合作和 互动。

PROJECT SUMMARY/ABSTRACT The mission of the proposed “Chemistry of Life Processes (CLP) Predoctoral Training Program” is to educate the next generation of transdisciplinary scientists that will be capable of extending and integrating the perspectives and approaches of the life sciences and chemistry to complex scientific problems in the field of biomedical research. The complex problems encountered across length and time scales in treating disease require a broad repertoire of skills along with the capacity to harness teams possessing a range of diverse expertise to advance the discovery of new therapeutics and diagnostics. In order to address the pressing public health needs of the 21st century, the next generation of researchers must be able to think and communicate in a common language that spans chemistry and biology. Renewal of the CLP Predoctoral Training Program will address this need by providing Northwestern University graduate students with the opportunity to integrate graduate studies in chemistry and the life sciences to a degree beyond that of any training program currently active at Northwestern University. The depth and breadth of its coursework requirements, novel immersive cross-disciplinary lab experience, and unique mentoring structure of the CLP program, coupled with a strong shared training environment, set this program apart from other Northwestern training programs in biomedical research. The program is built upon the highly collaborative, transdisciplinary biomedical research programs of 49 mentors with extensive expertise in the areas of drug development, synthetic biology, and potential molecular targets for therapeutic intervention. This application requests support for a total of 40 training slots over five years to create a vibrant cohort of peers with a common identity in sufficient numbers to support student-driven program activities. Trainees are appointed to the grant starting in the fall of their second year and are supported throughout the course of the second and third years of graduate education. Eight students will be supported annually in years 01-05. Ten additional students will be supported by one-year university fellowships. Northwestern's Chemistry of Life Processes Institute, the administrative home of the proposed training program, provides CLP trainees with a robust ecosystem for transdisciplinary research and training that is comprised of a highly collaborative team of faculty that span chemistry and the life sciences, unique shared resources that provide a seamless pipeline for drug discovery and development, an enabling infrastructure with expertise in development and management of education and training programs, extensive experience in translation of discoveries for the good of society, and a physical environment that drives transdisciplinary collaboration and interaction.