CAPRI: Columbia Cancer Training Program for Resident-Investigators

项目摘要/摘要 本申请旨在为住院医师建立哥伦比亚癌症培训计划 (Capri)在哥伦比亚大学医学中心(CUMC)和赫伯特·欧文综合癌症中心 (HICCC)，面向来自多个部门的居民。拟议中的计划将利用强大的 HICCC基础、临床/翻译和人口科学以及深部技术方面的教职员工 为医生提供癌症临床研究方面的高级培训。的主要目的是 CAPRI将提供最先进的临床设计、操作和伦理方面的综合培训 致力于临床癌症学术生涯的高积极性内科医生(医学博士或医学博士)的研究 医药。这项计划的基本原理是促进翻译研究人员的发展，这些研究人员来自 13个CUMC住院医师项目，包括皮肤科、内科、神经外科、产科/妇科、 眼科、整形外科、病理学、儿科、精神病学、放射肿瘤学、放射学 外科和泌尿科。有资格获得这笔补助金的驻地调查员被定义为未来的调查员和 以病人为中心的研究领域的领导者。CUMC的综合研究培训环境提供了 实现CAPRI目标的机会：医学博士在临床癌症领域的成功职业发展 专注于多学科团队科学的医学。卡普里将向驻地调查人员提供 执行最先进的临床研究所需的高级技能，并为他们提供以下能力： 1.设计和实施严格的假设驱动的研究，包括癌症护理连续体 预防、治疗、存活和姑息治疗，目标是降低死亡率和 这种疾病的发病率 2.将有希望的临床前和观察结果转化为癌症临床试验， 评估生物学和临床终点 3.在多学科团队中进行临床癌症研究，其中医生-科学家，基础 科学家和人口科学家协作和互动，以加速和加速翻译 将研究成果转化为临床环境

Project Summary/Abstract This application seeks to establish the Columbia Cancer Training Program for Resident-Investigators (CAPRI) at Columbia University Medical Center (CUMC) and the Herbert Irving Comprehensive Cancer Center (HICCC) for residents from multiple departments. The proposed program will take advantage of the strong HICCC faculty in basic, clinical/translational, and population sciences, as well as the deep technologic resources of CUMC to provide advanced training for physicians in clinical cancer research. The principal aim of CAPRI is to provide comprehensive training in the design, conduct, and ethics of state-of-the-art clinical research to highly motivated physicians (MD or MD-PhD) dedicated to academic careers in clinical cancer medicine. The rationale for this program is to facilitate the development of translational researchers drawn from 13 CUMC residency programs, including Dermatology, Medicine, Neurosurgery, Obstetrics/Gynecology, Ophthalmology, Orthopedic Surgery, Pathology, Pediatrics, Psychiatry, Radiation Oncology, Radiology, Surgery, and Urology. Resident-investigators eligible for this grant are defined as future investigators and leaders in patient-oriented research. The comprehensive research training environment at CUMC provides the opportunity to achieve the goals of CAPRI: the successful career development of MDs in clinical cancer medicine with a focus on multi-disciplinary team science. CAPRI will provide the resident-investigators with the advanced skills necessary to perform state-of-the-art clinical research and provide them with the ability to: 1. Design and conduct rigorous hypothesis-driven research that encompasses the cancer care continuum of prevention, treatment, survivorship, and palliative care with the goal of reducing mortality and morbidity from this disease 2. Translate promising pre-clinical and observational findings into cancer clinical trials that prospectively evaluate biological and clinical endpoints 3. Conduct clinical cancer research in a multi-disciplinary team setting in which physician-scientists, basic scientists, and population scientists collaborate and interact to expedite and accelerate the translation of research findings into the clinical setting