CAPRI: Columbia Cancer Training Program for Resident-Investigators

CAPRI：哥伦比亚癌症驻场调查员培训计划

• 批准号: 10186708
• 负责人: Katherine D Crew
• 金额: $ 35.8万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-09-15 至 2022-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10186708
• 关键词: Academic Medical Centers; Admission activity; American; Basic Science; Biological; Biometry; Cancer Biology; Clinical; Clinical Investigator; Clinical Research; Collaborations; Continuity of Patient Care; Couples; Dermatology; Development; Discipline; Discipline of obstetrics; Disease; Doctor of Philosophy; Environment; Epidemiology; Ethics; Faculty; Fellowship; Fellowship Program; Future; Goals; Grant; Gynecology; Health; Herbert Irving Comprehensive Cancer Center; Institutes; Institution; International; Malignant Neoplasms; Medicine; Mentors; Morbidity - disease rate; Nature; Oncology; Operative Surgical Procedures; Ophthalmology; Orthopedic Surgery; Outcomes Research; Palliative Care; Pathology; Pathway interactions; Pediatrics; Physicians; Population; Population Sciences; Positioning Attribute; Prevention; Psychiatry; Public Health; Public Health Schools; Radiation Oncology; Radiology Specialty; Records; Research; Research Personnel; Research Project Grants; Research Training; Residencies; Resources; Schools; Science; Scientist; Surgeon; Training; Training Programs; Translating; Translational Research; Universities; Urology; anticancer research; cancer care; cancer clinical trial; career; career development; clinically relevant; college; cost; design; innovation; investigator training; medical specialties; mortality; multidisciplinary; neurosurgery; next generation; patient oriented research; pre-clinical; programs; prospective; recruit; response; skills; survivorship; translational cancer research; translational scientist; tumor

Project Summary/Abstract This application seeks to establish the Columbia Cancer Training Program for Resident-Investigators (CAPRI) at Columbia University Medical Center (CUMC) and the Herbert Irving Comprehensive Cancer Center (HICCC) for residents from multiple departments. The proposed program will take advantage of the strong HICCC faculty in basic, clinical/translational, and population sciences, as well as the deep technologic resources of CUMC to provide advanced training for physicians in clinical cancer research. The principal aim of CAPRI is to provide comprehensive training in the design, conduct, and ethics of state-of-the-art clinical research to highly motivated physicians (MD or MD-PhD) dedicated to academic careers in clinical cancer medicine. The rationale for this program is to facilitate the development of translational researchers drawn from 13 CUMC residency programs, including Dermatology, Medicine, Neurosurgery, Obstetrics/Gynecology, Ophthalmology, Orthopedic Surgery, Pathology, Pediatrics, Psychiatry, Radiation Oncology, Radiology, Surgery, and Urology. Resident-investigators eligible for this grant are defined as future investigators and leaders in patient-oriented research. The comprehensive research training environment at CUMC provides the opportunity to achieve the goals of CAPRI: the successful career development of MDs in clinical cancer medicine with a focus on multi-disciplinary team science. CAPRI will provide the resident-investigators with the advanced skills necessary to perform state-of-the-art clinical research and provide them with the ability to: 1. Design and conduct rigorous hypothesis-driven research that encompasses the cancer care continuum of prevention, treatment, survivorship, and palliative care with the goal of reducing mortality and morbidity from this disease 2. Translate promising pre-clinical and observational findings into cancer clinical trials that prospectively evaluate biological and clinical endpoints 3. Conduct clinical cancer research in a multi-disciplinary team setting in which physician-scientists, basic scientists, and population scientists collaborate and interact to expedite and accelerate the translation of research findings into the clinical setting

项目总结/文摘

项目成果

A novel CNN algorithm for pathological complete response prediction using an I-SPY TRIAL breast MRI database.

使用I-SPY试验乳腺MRI数据库的新型CNN算法用于病理完全反应预测。

• DOI: 10.1016/j.mri.2020.08.021
• 发表时间: 2020-11
• 期刊: Magnetic resonance imaging
• 影响因子: 2.5
• 作者: Liu MZ;Mutasa S;Chang P;Siddique M;Jambawalikar S;Ha R
• 通讯作者: Ha R

Endoscopic endonasal approach for suprasellar meningiomas: introduction of a new scoring system to predict extent of resection and assist in case selection with long-term outcome data.

内窥镜上脑脑脑膜瘤的内窥镜鼻鼻方法：引入一种新的评分系统，以预测切除程度并帮助选择长期结果数据。

• DOI: 10.3171/2020.4.jns20475
• 发表时间: 2021-07-01
• 期刊: Journal of neurosurgery
• 影响因子: 4.1
• 作者: Youngerman BE;Banu MA;Gerges MM;Odigie E;Tabaee A;Kacker A;Anand VK;Schwartz TH
• 通讯作者: Schwartz TH

Right occipital transtentorial approach for a pineal malignant germ cell tumor.

• DOI: 10.3171/2021.4.focvid2151
• 发表时间: 2021-07
• 期刊: Neurosurgical focus: Video
• 作者: Gill, Brian J A;Higgins, Dominique M;Banu, Matei A;Argenziano, Michael G;Feldstein, Neil A;Bruce, Jeffrey N
• 通讯作者: Bruce, Jeffrey N

Convolutional Neural Network Using a Breast MRI Tumor Dataset Can Predict Oncotype Dx Recurrence Score.

• DOI: 10.1002/jmri.26244
• 发表时间: 2019-03
• 期刊: Journal of magnetic resonance imaging : JMRI
• 作者: Ha R;Chang P;Mutasa S;Karcich J;Goodman S;Blum E;Kalinsky K;Liu MZ;Jambawalikar S
• 通讯作者: Jambawalikar S

On precision dosing of oral small molecule drugs in oncology.

• DOI: 10.1111/bcp.14454
• 发表时间: 2021-03
• 期刊: British journal of clinical pharmacology
• 影响因子: 3.4
• 作者: Lyashchenko AK;Cremers S
• 通讯作者: Cremers S