Pilot Study to Determine Health Effects of e-cigarette in Healthy Young Adults

确定电子烟对健康年轻人健康影响的试点研究

• 批准号: 10198248
• 负责人: Donald E Brown
• 金额: $ 41.49万
• 依托单位: UNIVERSITY OF VIRGINIA
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-02-27 至 2024-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10198248
• 关键词: Achievement; Algorithms; Clinical; Clinical Research; Clinical Trials; Clinical Trials Design; Collaborations; Communication; Communities; Data; Data Analyses; Data Analytics; Data Commons; Data Science; Data Scientist; Data Set; Electronic cigarette; Ethics; Foundations; Funding; Geographic Locations; Goals; Health; Health system; Healthcare; Human; Informatics; Infrastructure; Institutes; Institution; Insurance Carriers; Intervention; Learning; Licensing; Location; Longevity; Methods; Mission; Patients; Personal Satisfaction; Phase; Pilot Projects; Population; Privatization; Process; Reproducibility; Research; Research Activity; Research Infrastructure; Research Institute; Research Methodology; Research Personnel; Resources; Rural; Rural Population; Science; Scientist; Secure; Services; Site; Source; Speed; System; Technology; Therapeutic; Thinness; Training; Training Support; Translational Research; United States National Institutes of Health; Universities; Urban Population; Virginia; Workforce Development; base; career development; data access; data modeling; data sharing; design; health data; improved; informatics infrastructure; innovation; mHealth; member; mobile application; models and simulation; multidisciplinary; named group; next generation; novel; open data; personalized approach; programs; sharing platform; system architecture; telehealth; tool; translational scientist; wearable device; young adult

The integrated Translational Health Research Institute of Virginia (iTHRIV) program is a collaboration of public and private institutions across the Commonwealth of Virginia that brings team science, innovation, and a commitment to train the next generation of clinical and translational researchers. Our three iTHRIV partners include University of Virginia (Central VA), Virginia Tech Carilion (Southwestern VA) and Inova Health Systems (Northern VA). Our two iTHRIV affiliates are the Center for Open Science and the Licensing and Ventures Group in Charlottesville. A particular strength of iTHRIV lies in integrating data science approaches through all aspects of clinical translational research in order to speed discovery and improve the health of our communities. iTHRIV has a central tenant that serves as the organizing principle: health care solutions are hidden in underutilized data. Our overall goal is to deepen the iTHRIV infrastructure to support clinical translational research to benefit the diverse rural and urban populations that iTHRIV member clinicians serve. The unified approach across the components of this CTSA application is to integrate data and data analytics to accelerate and streamline scientific workflows for clinical trials, innovative therapeutic advancements, and the creation of more personalized approaches to healthcare. Data science is a particular strength of our team and will allow us to transform our cross-state informatics infrastructure by creating The Commons, a scalable research hosting platform shared by iTHRIV partners that will serve as the foundation for our informatics support. It will provide the infrastructure for the Research Concierge Services, the human and electronic approach to supporting clinical translational research. This platform will combine data-centered approaches to discovery by hosting and sharing datasets, applications, and other research objects with a humancentered approach to design and systems architecture. The Commons is designed to serve both as a technical framework and an approach to establishing processes and tools necessary to enable data sharing between partner locations. The Concierge service informs and connects researchers to training, support services and compliance resources to streamline the clinical translational research process. The mission of iTHRIV, through the Commons and the Concierge Services, is to remove barriers to discovery in Virginia and beyond. The iTHRIV Commons is conceptually similar to the NIH Data Commons, and the implementation of this framework across partner sites will remove barriers to data access and other research objects (algorithms, best practices, etc.), while enforcing compliance in the secure use of data. iTHRIV will marry the expertise of our world class data science teams in The Commons to our outstanding clinical translational researchers in order to uncover health care solutions.

弗吉尼亚州综合转化健康研究所（iTHRIV）计划是一个合作项目， 弗吉尼亚联邦的公共和私人机构，带来了团队科学，创新， 并致力于培养下一代临床和转化研究人员。我们的三个iTHRIV 合作伙伴包括弗吉尼亚大学（弗吉尼亚州中部）、弗吉尼亚理工大学（弗吉尼亚州西南部）和Inova 卫生系统（弗吉尼亚州北方）。我们的两个iTHRIV分支机构是开放科学中心和 许可和风险投资集团在夏洛茨维尔。iTHRIV的一个特殊优势在于整合数据 科学方法贯穿临床转化研究的各个方面，以加速发现， 改善我们社区的健康。iTHRIV有一个中央租户， 原则：医疗保健解决方案隐藏在未充分利用的数据中。我们的总体目标是深化iTHRIV 支持临床转化研究的基础设施，以造福不同的农村和城市人口 iTHRIV成员临床医生服务。本CTSA各组成部分的统一方法 应用程序是集成数据和数据分析，以加速和简化科学工作流程 临床试验，创新的治疗进展，并创造更个性化的 接近医疗保健。数据科学是我们团队的一个特殊优势，它将使我们能够 通过创建共享资源，一个可扩展的研究， iTHRIV合作伙伴共享的托管平台将作为我们信息支持的基础。它 将为研究咨询服务提供基础设施，人力和电子方法 支持临床转化研究。该平台将结合联合收割机以数据为中心的方法， 通过托管和共享数据集，应用程序和其他研究对象，以人为本， 设计方法和系统架构。下议院的目的是作为一个 技术框架和建立必要程序和工具的方法， 在合作伙伴之间共享。Conclusion服务为研究人员提供信息并将其与培训联系起来， 支持服务和合规资源，以简化临床转化研究流程。的 iTHRIV的使命是通过公共资源和公共服务消除发现的障碍 在弗吉尼亚州和更远的地方iTHRIV Commons在概念上类似于NIH Data Commons， 在各伙伴地点实施这一框架将消除数据访问和其他方面的障碍， 研究对象（算法、最佳实践等），同时在数据的安全使用中强制遵守。 iTHRIV将把我们世界一流的数据科学团队的专业知识与我们的 杰出的临床转化研究人员，以发现医疗保健解决方案。