Advancing Geriatrics Infrastructure and Network Growth (AGING) Initiative

项目摘要/摘要： HCSRN-OAICs老龄化倡议寻求行政补充(PA-18-591/NOT-AG-20-022)以 R33AG057806，解决与预防、控制、管理和 新冠肺炎在养老院的治疗情况如：中小养老院有哪些特点 与老龄倡议合作伙伴相关的养老院集群？；与新冠肺炎相关的内容 直接适用于疗养院居民的护理和福祉的研究问题将是 在目前的大流行背景下，最优先和最值得研究的是什么？ 在养老院开展新冠肺炎相关研究的障碍和挑战？ 被要求创建疗养院临床试验网络，该网络由以下几个小到中等规模的集群组成 与老龄化倡议合作伙伴相关的养老院？“先进的老年医学基础设施” 和网络增长“(老龄化)倡议汇集了卫生保健系统研究网络(HCSRN) OAICs将推进一项跨学科研究议程，重点研究患有多发性多发性硬化症的老年人 条件(MCC)。老龄化倡议R33的具体目标是：(1)扩大和进一步发展 与测量和分析、观察性研究和实用临床试验相关的创新方法 设计和实施，为改善护理的新干预措施的开发和测试提供信息 (2)促进新的和早期的老年人的职业发展和成功- 阶段调查员，包括代表性不足的少数族裔；(3)创建新的核心职能，作为 精心设计的基础设施，通过让患者和护理合作伙伴全方位参与，促进以患者为中心的研究 研究过程的各个阶段；以及(4)资助一系列的“P-2-R”(“飞行员到R奖”)补助金。建议数 行政副刊建立在父项目(R33AG057806)的基础上，方法是：(1)解决以下研究课题 与患有多种慢性病(MCC)的老年人至关重要--新奇的破坏性影响 疗养院冠状病毒2019(新冠肺炎)；(2)评估应对新方法和途径 与患有MCC的老年人有关的研究问题；(3)促进新的合作和伙伴关系，以 促进监控化学品的科学研究；和(4)鼓励研究，最终将转化为 为包括养老院居民在内的弱势群体提供更高质量的护理。

PROJECT SUMMARY/ABSTRACT: The HCSRN-OAICs AGING Initiative seeks an administrative supplement (PA-18-591/NOT-AG-20-022) to R33AG057806 to address pressing research questions related to prevention, control, management, and treatment of COVID-19 in nursing homes, such as: What are the characteristics of the small to modest-sized clusters of nursing homes that are associated with the AGING Initiative partners?; What COVID-19 related research questions, with direct applicability to the care and well-being of nursing home residents, would be of the highest priority and most amenable to study in the context of the ongoing pandemic?; What are the current barriers and challenges to conducting COVID-19 related research in nursing homes?; and What steps would be required to create a nursing home clinical trials network comprised of the small to modest-sized clusters of nursing homes that are associated with the AGING Initiative partners? The “Advancing Geriatrics Infrastructure and Network Growth” (AGING) Initiative brings together the Health Care Systems Research Network (HCSRN) and the OAICs to advance an interdisciplinary research agenda focused on older adults with multiple chronic conditions (MCCs). The specific aims under the AGING Initiative R33 are: (1) to expand on and further develop innovative methods related to measurement and analytics, observational research, and pragmatic clinical trial design and implementation, to inform the development and testing of novel interventions that improve the care and outcomes of older persons with MCCs; (2) to foster the career development and success of new and early- stage investigators, including underrepresented minorities; (3) to create a new core function as part of an elaborated infrastructure that promotes patient-centered research by engaging patients and care partners in all stages of the research process; and (4) to fund a series of “P-2-R” (“Pilot-to-R award”) grants. The proposed administrative supplement builds on the parent project (R33AG057806) by: (1) addressing a research topic of vital relevance to older adults with multiple chronic conditions (MCCs) – the devastating impact of novel coronavirus 2019 (COVID-19) in nursing homes; (2) assessing new methods and approaches addressing research questions relevant to older adults with MCCs; (3) promoting new collaborations and partnerships to advance the science of MCCs; and (4) encouraging research that will ultimately translate into the delivery of higher quality care for vulnerable populations including residents of nursing homes.