Advancing Geriatrics Infrastructure and Network Growth (AGING) Initiative

项目总结/摘要： HCSRN-OAIC老龄化倡议寻求行政补充（PA-18-591/NOT-AG-20-022）， R33 AG 057806解决与预防、控制、管理和 护理院的COVID-19治疗，例如：小型到中型的特点是什么 与老龄化倡议合作伙伴有关的疗养院集群？什么COVID-19相关 研究问题直接适用于疗养院居民的护理和福祉，将是 在当前流行病的背景下，最优先考虑和最适合研究的是什么？目前有哪些 在养老院进行COVID-19相关研究的障碍和挑战？哪些步骤将 需要创建一个由小型到中型集群组成的养老院临床试验网络， 与老龄化倡议合作伙伴有关的养老院？“推进老年医学基础设施 和网络增长”（老龄化）倡议汇集了卫生保健系统研究网络（HCSRN） 和OAIC推进跨学科研究议程，重点关注患有多种慢性疾病的老年人 条件（MCC）。老龄问题倡议R33的具体目标是：（1）扩大和进一步发展 与测量和分析、观察性研究和实用临床试验相关的创新方法 设计和实施，为开发和测试新的干预措施提供信息， （2）促进新的和早期的社区参与者的职业发展和成功， 阶段调查员，包括代表性不足的少数民族;（3）创建一个新的核心职能，作为 精心设计的基础设施，通过让患者和护理合作伙伴参与所有研究，促进以患者为中心的研究 （4）资助一系列“P-2-R”（“Pilot-to-R奖”）赠款。拟议 行政补充以母项目（R33 AG 057806）为基础：（1）解决以下研究主题 与患有多种慢性疾病（MCC）的老年人的重要相关性-新的 2019冠状病毒（COVID-19）在疗养院;（2）评估新的方法和途径，解决 与老年MCC患者相关的研究问题;（3）促进新的合作和伙伴关系， 推进监控化学品科学;（4）鼓励研究，最终将转化为交付 为包括疗养院居民在内的弱势群体提供更高质量的护理。

PROJECT SUMMARY/ABSTRACT: The HCSRN-OAICs AGING Initiative seeks an administrative supplement (PA-18-591/NOT-AG-20-022) to R33AG057806 to address pressing research questions related to prevention, control, management, and treatment of COVID-19 in nursing homes, such as: What are the characteristics of the small to modest-sized clusters of nursing homes that are associated with the AGING Initiative partners?; What COVID-19 related research questions, with direct applicability to the care and well-being of nursing home residents, would be of the highest priority and most amenable to study in the context of the ongoing pandemic?; What are the current barriers and challenges to conducting COVID-19 related research in nursing homes?; and What steps would be required to create a nursing home clinical trials network comprised of the small to modest-sized clusters of nursing homes that are associated with the AGING Initiative partners? The “Advancing Geriatrics Infrastructure and Network Growth” (AGING) Initiative brings together the Health Care Systems Research Network (HCSRN) and the OAICs to advance an interdisciplinary research agenda focused on older adults with multiple chronic conditions (MCCs). The specific aims under the AGING Initiative R33 are: (1) to expand on and further develop innovative methods related to measurement and analytics, observational research, and pragmatic clinical trial design and implementation, to inform the development and testing of novel interventions that improve the care and outcomes of older persons with MCCs; (2) to foster the career development and success of new and early- stage investigators, including underrepresented minorities; (3) to create a new core function as part of an elaborated infrastructure that promotes patient-centered research by engaging patients and care partners in all stages of the research process; and (4) to fund a series of “P-2-R” (“Pilot-to-R award”) grants. The proposed administrative supplement builds on the parent project (R33AG057806) by: (1) addressing a research topic of vital relevance to older adults with multiple chronic conditions (MCCs) – the devastating impact of novel coronavirus 2019 (COVID-19) in nursing homes; (2) assessing new methods and approaches addressing research questions relevant to older adults with MCCs; (3) promoting new collaborations and partnerships to advance the science of MCCs; and (4) encouraging research that will ultimately translate into the delivery of higher quality care for vulnerable populations including residents of nursing homes.