Ophthalmology and Visual Sciences Career Development K12 Program

项目概要/摘要 NEI指导临床科学家发展计划奖在UCSD的总体目标是发展 优秀的临床科学家成功竞争NIH赠款，并成为学术界的领导者 眼科通过这个机构职业发展奖，我们将继续指导临床医生 科学家在眼科学中的独立学术任命。自1991年以来，UC San Diego Shiley 眼科研究所在指导整个眼科临床科学家的职业发展方面表现出色。 其中许多人现在在世界各地拥有成功的研究和临床事业;他们包括 系主任，部门负责人，和有影响力的院士。通过持续的资金投入，我们将扩大这些 通过指导，研究和教育的结构化计划，以确定和指导下一个 新一代的学术临床科学家，跨越眼科学的所有子专业领域。 重点是从女性和少数族裔申请人中招募优秀的申请人， 每年在完成眼科住院医师临床研究后被选中。这位学者 将在适合其科学重点的基础和/或临床科学领域开展这些活动， 并与导师合作，促进职业发展。每位学者将接受临床培训， 相关研究，统计，科学写作，拨款准备，道德，领导力和负责任的行为 的研究。每个学者的课程的其他方面将由项目主任个性化 (PI)、研究总监、教育总监、执行委员会、指导小组和基于 根据学者选择的主要研究方向和他/她的技能，背景和职业目标。每个 学者将创建一个原创的研究计划，并通过这个奖项发展一个独立的学术 事业 我们提出了六个主要的研究方向：（1）视觉神经科学，（2）基因组学和蛋白质组学，（3） 生物工程，（4）干细胞生物学，（5）人工智能和信息学，（6）临床（人类受试者） Research. 在第一个K12资助期内，我们培训并招募了四名视网膜亚专业领域的临床科学家 (2)、青光眼（1）和小儿眼科（1）。其中两名学者已经获得了NIH K 08 其他两个已经提交了K 08提案，正在考虑中。

PROJECT SUMMARY / ABSTRACT The overall objective of the NEI Mentored Clinical Scientist Development Program Award at UCSD is to develop outstanding clinician scientists to successfully compete for NIH grants and emerge as leaders within academic ophthalmology. Through this institutional career development award, we will continue to mentor clinician scientists toward independent academic appointments in ophthalmology. Since 1991, the UC San Diego Shiley Eye Institute has excelled in mentoring the career development of clinician scientists throughout ophthalmology. Many of these individuals now have successful research and clinical careers around the world; they include Department Chairs, Division Chiefs, and impactful academicians. With continued funding, we will amplify these strengths through a structured program of mentoring, research, and education to identify and mentor the next generation of academic clinician scientists, across all subspecialty areas of ophthalmology. With an emphasis on recruiting strong applications from women and minority applicants, Scholars will be selected each year after their completion of a post-residency clinical fellowship in ophthalmology. The Scholar will undertake these activities in the area of basic and/or clinical sciences appropriate to their scientific focus, and by partnering with mentor(s) to facilitate career development. Each Scholar will be trained in clinically relevant research, statistics, scientific writing, grant preparation, ethics, leadership, and the responsible conduct of research. Additional aspects of the curriculum of each Scholar will be individualized by the Program Director (PI), Research Directors, Education Director, Executive Committee, Mentoring Group, and lead mentor based upon the Scholar's selected primary research track and his/her skills, background, and career goals. Each Scholar will create an original research program and through this Award develop an independent academic career. We propose six primary research tracks: (1) Visual Neuroscience, (2) Genomics and Proteomics, (3) Bioengineering, (4) Stem Cell Biology, (5) Artificial Intelligence and Informatics, and (6) Clinical (human subjects) Research. In the first K12 funding period, we trained and recruited four clinician scientists in the subspecialty areas of retina (2), glaucoma (1), and pediatric ophthalmology (1). Two of these Scholars already have received NIH K08 awards, and the other two have submitted K08 proposals that are under consideration.