Childhood Obesity Research Core

摘要/概要- CORC 新提出的儿童肥胖研究核心（CORC）的目标是支持一个 为基础、临床和转化研究人员提供强大的转化研究基础设施 关注儿童营养和肥胖问题。CORC利用 动量中心的成就，一个大学范围和跨学科的儿童肥胖 该中心成立于2013年，提供研究基础设施，资金和推广， 儿童肥胖研究人员和MNORC成员。CORC解决主要障碍 密歇根大学的儿童肥胖调查人员发现， 研究障碍：访问电子健康记录（EHR）数据进行研究的障碍， 识别和访问独特的儿童群体以进行观察和 干预性研究，以及为研究任务/研究开发卫生信息技术工具的障碍。 因此，CORC利用强大的健康信息技术（IT）生态系统， 密歇根医学作为一个平台，进行嵌入式转化研究， 医疗保健提供系统。研究人员将获得： (1)访问密歇根州超过20万名儿童的EHR数据集中存储库 2012年至今的医学，并有机会利用知识库来支持 前瞻性和干预性临床，行为和健康结果研究， 目前在9个社区中看到的41，000多名儿童的纵向队列 初级保健儿科诊所，其中10，000多个与孕产妇健康数据有联系; (2)支持将儿童肥胖症研究纳入提供系统的服务 包括设计和开发面向提供者和患者的定制医疗信息技术工具; 就研究设计、IRB和数据分析提供咨询;获取新生儿筛查标本 和国家EHR数据;以及支持受试者招募和协调生物标本 收集;及 (3)访问本地和国际儿科和孕产妇的现有数据和生物标本 研究组的重点是营养、肥胖、生长和发育。

Abstract/Summary - CORC The goal of the newly proposed Childhood Obesity Research Core (CORC) is to support a robust translational research infrastructure for basic, clinical, and translational researchers focused on childhood nutrition and obesity. The CORC takes advantage of the accomplishments of Momentum Center, a university-wide and interdisciplinary childhood obesity center established in 2013, which has provided research infrastructure, funding, and outreach to childhood obesity researchers and MNORC members. The CORC addresses major barriers identified by childhood obesity investigators at the University of Michigan, related to following barriers to research: barriers with accessing electronic health record (EHR) data for research, barriers with identifying and accessing unique populations of children for observational and interventional studies, and barriers with developing health IT tools for research tasks/studies. The CORC therefore leverages the robust health information technology (IT) ecosystem at Michigan Medicine as a platform for conducting translational research embedded in the healthcare delivery system. Researchers will be provided with: (1) Access to a centralized repository of EHR data for over 200,000 children seen at Michigan Medicine between 2012 to present, and the opportunity to utilize the repository to support prospective and interventional clinical, behavioral, and health outcomes research in a longitudinal cohort of over 41,000+ children currently being seen across nine community-based primary care pediatric clinics, of whom 10,000+ have linkages to maternal health data; (2) Services to support the integration of childhood obesity research into the delivery system including the design and development of customized provider- and patient-facing health IT tools; consultation on study design, IRB, and data analysis; access to newborn screening specimens and national EHR data; and support for subject recruitment and coordinated biospecimen collection; and (3) Access to existing data and biospecimens from local and international pediatric and maternal cohorts focused on nutrition, obesity, growth, and development.