Graduate Training Program in Quantitative and Chemical Biology at Indiana University Bloomington

在这项提案中，来自化学系的三十四位高度合作的导师， 生物学和物理学以及三个不同的研究生课程，生物化学，细胞，分子和癌症 位于布卢明顿的印第安纳州大学的生物学（CMCB）和神经科学，已经联合起来，继续 在定量和化学生物学的化学生物学接口（CBI）提供博士前培训 （QCB）。我们的培训使命是改变我们校园分子科学的研究生教育， 通过促进化学、物理和生物领域的跨学科和合作研究培训， 解决生物学和医学中的重要问题。该程序通过提供一个 在化学和物理生物学的核心教学和课外经验，无缝集成 量化和严格的培训，进入传统学科定义的六个博士-授予学位 提名学生获得支持的项目。该方案是由一个项目主任和一个共同指导， 主任，各自在物理和化学生物学方面具有互补的专业知识，并由一名 指导委员会，包括来自所有六个参与部门和方案的导师。的 招募委员会负责识别和招募学生支持该计划。 课程委员会会继续监督品质保证局制作新的主题电子单元的工作 学生，而QCB培训教师教两个1.5学分的核心课程，介绍定量 生物学和测量（C680）和介绍化学生物学I（C681），以及QCB杂志 俱乐部（C689）。课外活动包括QCB受训者邀请研讨会系列， QCB晚会，每月一次的“超级小组”研究研讨会系列，这两个都是完全由 我们不断壮大的QCB实习生队伍，由两位QCB（实习生）大使带领。培训计划 还举办了一年一度的渡边化学生物学研讨会，该研讨会汇集了国际知名的 来自学术界和工业界的科学家到布卢明顿与QCB学员建立联系。我们的节目 为学员提供重要的职业发展机会，并享有强大的行政管理能力。 来自艺术与科学学院的支持，该学院在五年内承诺了十个匹配的名额- 年项目周期。目前的NIGMS和学院支持已被用来支持一个高度多样化的 到目前为止（2014-2018年），这批学员在他们的研究生职业生涯的第2-3年中学习了1-2年。一个主要 目标是显着多样化的化学，物理和生物科学在IU;全面 提供多样性招聘和培训生保留计划， 大学研究生院对一个代表性不足的团体实习生的支持，将使我们能够实现这一目标。 objective.负责任的研究行为的教学计划和提高 还提供了生殖器。

In this proposal, thirty-four highly collaborative preceptors drawn from the Departments of Chemistry, Biology and Physics and three different graduate programs, in Biochemistry, Cell, Molecular and Cancer Biology (CMCB) and Neuroscience, at Indiana University, Bloomington, have joined forces to continue to provide predoctoral training at the chemistry-biology interface (CBI) in Quantitative and Chemical Biology (QCB). Our training mission is to transform graduate education in the molecular sciences on our campus, by facilitating interdisciplinary and collaborative research training in the chemical, physical and biological sciences to address important problems in biology and medicine. The program does this by providing a core didactic and extracurricular experience in chemical and physical biology that seamlessly integrates quantitative and rigorous training into traditional disciplines defined by the six Ph.D.-granting graduate programs that nominate students for support. The program is directed by a Program Director and a Co- Director, each with complementary expertise in physical and chemical biology, and is overseen by a Steering Committee that includes preceptors from all six participating departments and programs. The Recruitment Committee is charged with identifying and recruiting students for support by the program. The Curriculum Committee will continue to oversee the creation of new topics-based e-modules by QCB students, while QCB training faculty teach two 1.5 credit core courses, Introduction to Quantitative Biology and Measurement (C680) and Introduction to Chemical Biology I (C681), as well as QCB Journal Club (C689). Extracurricular programmatic activities include a QCB trainee-Invited Seminar Series and QCB Evenings, a monthly “super-group” research seminar series, both of which are entirely organized by our growing QCB trainee cohort, spearheaded by two QCB (trainee) Ambassadors. The training program also hosts the annual Watanabe Symposium in Chemical Biology, which brings internationally prominent scientists to Bloomington from academia and industry alike to network with QCB trainees. Our program provides significant career development opportunities for trainees, and enjoys strong administrative support from the College of Arts and Sciences, which has committed ten matching slots over the five- year project period. Current NIGMS and College support have been used to support a highly diverse cohort of trainees thus far (2014-2018) for 1-2 years in years 2-3 of their graduate careers. A major objective is to significantly diversify the chemical, physical and biological sciences at IU; comprehensive diversity recruitment and trainee retention plans are provided, which when coupled with proactive University Graduate School support of an underrepresented group trainee, will allow us to achieve this objective. Plans for instruction in the Responsible Conduct of Research and Methods for Enhancing Reproducibility are also provided.