Graduate Training Program in Quantitative and Chemical Biology at Indiana University Bloomington

在这项提案中，来自化学系的34名高度合作的教官， 生物学、物理学和三个不同的研究生课程：生物化学、细胞、分子和癌症 印第安纳大学布鲁明顿分校的生物学(CMCB)和神经科学已经联合起来，继续 在化学-生物学接口(CBI)提供定量和化学生物学方面的博士前培训 (QCB)。我们的培训使命是改变我们校园里分子科学的研究生教育， 通过促进化学、物理和生物方面的跨学科和协作研究培训 科学来解决生物学和医学中的重要问题。该程序通过提供一个 化学和物理生物学的核心教学和课外经验，无缝整合 对六名授予博士学位的毕业生定义的传统学科进行量化和严格的培训 提名学生以获得支持的计划。该计划由一名计划总监和一名联合- 两人在物理和化学生物学方面都有互补的专业知识，并由一名 指导委员会，包括来自所有六个参与部门和方案的导师。这个 招生委员会负责识别和招收学生以获得该计划的支持。 课程委员会将继续监督QCB创建以主题为基础的新电子单元 学生，而QCB培训人员教授两门1.5学分核心课程，量化导论 《生物与测量》(C680)和《化学生物学导论》I(C681)以及QCB期刊 俱乐部(C689)。课外方案活动包括QCB实习生邀请研讨会系列和 QCB Evenings，每月一次的“超级小组”研究研讨会系列，这两个研讨会都完全由 我们不断壮大的QCB实习生队伍，由两位QCB(实习生)大使带头。培训计划 还主持一年一度的渡边化学生物学研讨会，该研讨会带来了国际知名的 从学术界和工业界的科学家到布卢明顿，再到与QCB学员建立网络。我们的节目 为学员提供重要的职业发展机会，并享有很强的行政管理能力 来自艺术与科学学院的支持，该学院承诺在五年内提供十个匹配的名额- 年项目期。目前的NIGMS和学院支持已用于支持高度多样化的 到目前为止(2014-2018年)的受训者队列，为期1-2年，在他们毕业生涯的第2-3年。一位少校 目标是使印第安纳大学的化学、物理和生物科学显著多样化；全面 提供多样化招聘和实习生保留计划，当这些计划与前瞻性相结合时 大学研究生院对代表不足的团体实习生的支持，将使我们能够实现这一目标 目标。负责任地开展研究的指导计划和加强 还提供了重复性。

In this proposal, thirty-four highly collaborative preceptors drawn from the Departments of Chemistry, Biology and Physics and three different graduate programs, in Biochemistry, Cell, Molecular and Cancer Biology (CMCB) and Neuroscience, at Indiana University, Bloomington, have joined forces to continue to provide predoctoral training at the chemistry-biology interface (CBI) in Quantitative and Chemical Biology (QCB). Our training mission is to transform graduate education in the molecular sciences on our campus, by facilitating interdisciplinary and collaborative research training in the chemical, physical and biological sciences to address important problems in biology and medicine. The program does this by providing a core didactic and extracurricular experience in chemical and physical biology that seamlessly integrates quantitative and rigorous training into traditional disciplines defined by the six Ph.D.-granting graduate programs that nominate students for support. The program is directed by a Program Director and a Co- Director, each with complementary expertise in physical and chemical biology, and is overseen by a Steering Committee that includes preceptors from all six participating departments and programs. The Recruitment Committee is charged with identifying and recruiting students for support by the program. The Curriculum Committee will continue to oversee the creation of new topics-based e-modules by QCB students, while QCB training faculty teach two 1.5 credit core courses, Introduction to Quantitative Biology and Measurement (C680) and Introduction to Chemical Biology I (C681), as well as QCB Journal Club (C689). Extracurricular programmatic activities include a QCB trainee-Invited Seminar Series and QCB Evenings, a monthly “super-group” research seminar series, both of which are entirely organized by our growing QCB trainee cohort, spearheaded by two QCB (trainee) Ambassadors. The training program also hosts the annual Watanabe Symposium in Chemical Biology, which brings internationally prominent scientists to Bloomington from academia and industry alike to network with QCB trainees. Our program provides significant career development opportunities for trainees, and enjoys strong administrative support from the College of Arts and Sciences, which has committed ten matching slots over the five- year project period. Current NIGMS and College support have been used to support a highly diverse cohort of trainees thus far (2014-2018) for 1-2 years in years 2-3 of their graduate careers. A major objective is to significantly diversify the chemical, physical and biological sciences at IU; comprehensive diversity recruitment and trainee retention plans are provided, which when coupled with proactive University Graduate School support of an underrepresented group trainee, will allow us to achieve this objective. Plans for instruction in the Responsible Conduct of Research and Methods for Enhancing Reproducibility are also provided.