Graduate Training Program in Quantitative and Chemical Biology at Indiana University Bloomington

印第安纳大学伯明顿分校定量和化学生物学研究生培训项目

• 批准号: 10412039
• 负责人: DAVID P. GIEDROC
• 金额: $ 31.22万
• 依托单位: TRUSTEES OF INDIANA UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-07-01 至 2024-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10412039
• 关键词: Biology; Chemicals; Indiana; Training Programs; Universities

In this proposal, thirty-four highly collaborative preceptors drawn from the Departments of Chemistry, Biology and Physics and three different graduate programs, in Biochemistry, Cell, Molecular and Cancer Biology (CMCB) and Neuroscience, at Indiana University, Bloomington, have joined forces to continue to provide predoctoral training at the chemistry-biology interface (CBI) in Quantitative and Chemical Biology (QCB). Our training mission is to transform graduate education in the molecular sciences on our campus, by facilitating interdisciplinary and collaborative research training in the chemical, physical and biological sciences to address important problems in biology and medicine. The program does this by providing a core didactic and extracurricular experience in chemical and physical biology that seamlessly integrates quantitative and rigorous training into traditional disciplines defined by the six Ph.D.-granting graduate programs that nominate students for support. The program is directed by a Program Director and a Co- Director, each with complementary expertise in physical and chemical biology, and is overseen by a Steering Committee that includes preceptors from all six participating departments and programs. The Recruitment Committee is charged with identifying and recruiting students for support by the program. The Curriculum Committee will continue to oversee the creation of new topics-based e-modules by QCB students, while QCB training faculty teach two 1.5 credit core courses, Introduction to Quantitative Biology and Measurement (C680) and Introduction to Chemical Biology I (C681), as well as QCB Journal Club (C689). Extracurricular programmatic activities include a QCB trainee-Invited Seminar Series and QCB Evenings, a monthly “super-group” research seminar series, both of which are entirely organized by our growing QCB trainee cohort, spearheaded by two QCB (trainee) Ambassadors. The training program also hosts the annual Watanabe Symposium in Chemical Biology, which brings internationally prominent scientists to Bloomington from academia and industry alike to network with QCB trainees. Our program provides significant career development opportunities for trainees, and enjoys strong administrative support from the College of Arts and Sciences, which has committed ten matching slots over the five- year project period. Current NIGMS and College support have been used to support a highly diverse cohort of trainees thus far (2014-2018) for 1-2 years in years 2-3 of their graduate careers. A major objective is to significantly diversify the chemical, physical and biological sciences at IU; comprehensive diversity recruitment and trainee retention plans are provided, which when coupled with proactive University Graduate School support of an underrepresented group trainee, will allow us to achieve this objective. Plans for instruction in the Responsible Conduct of Research and Methods for Enhancing Reproducibility are also provided.

在这项提案中，来自化学系的三十四名高度合作的导师， 生物学和物理学以及生物化学、细胞、分子和癌症三个不同的研究生课程 印第安纳大学伯明顿分校的生物学 (CMCB) 和神经科学联手继续 在定量和化学生物学领域的化学-生物学接口（CBI）提供博士前培训 （QCB）。我们的培训使命是改变我们校园分子科学的研究生教育， 通过促进化学、物理和生物领域的跨学科和协作研究培训 科学来解决生物学和医学中的重要问题。该程序通过提供一个 化学和物理生物学的核心教学和课外经验无缝整合 对六名博士授予毕业生定义的传统学科进行定量和严格的培训 提名学生支持的计划。该计划由一名计划主任和一名联合主任指导 主任各自在物理和化学生物学方面具有互补的专业知识，并由一名 指导委员会包括来自所有六个参与部门和项目的导师。这 招生委员会负责识别和招募学生以获得该计划的支持。 课程委员会将继续监督 QCB 创建新的基于主题的电子模块 学生，而 QCB 培训教师教授两门 1.5 学分的核心课程：定量导论 生物学和测量 (C680) 和化学生物学概论 I (C681)，以及 QCB 期刊 俱乐部（C689）。课外活动包括 QCB 受训者邀请研讨会系列和 QCB 之夜，每月一次的“超级团体”研究研讨会系列，两者完全由 我们不断壮大的 QCB 实习生队伍，由两名 QCB（实习生）大使带头。培训计划 还主办了年度化学生物学渡边研讨会，该研讨会汇聚了国际知名人士 来自学术界和工业界的科学家来到布卢明顿与 QCB 学员建立联系。我们的计划 为学员提供重要的职业发展机会，并享有强大的行政管理 艺术与科学学院的支持，该学院在五个项目中承诺了十个匹配名额 年项目期。当前的 NIGMS 和大学支持已用于支持高度多样化的 迄今为止（2014-2018）的一批学员在其研究生职业生涯的第 2-3 年中为期 1-2 年。一个专业 目标是使印第安纳大学的化学、物理和生物科学显着多样化；综合的 提供多元化招聘和实习生保留计划，再加上积极主动的 大学研究生院对代表性不足的团体实习生的支持将使我们能够实现这一目标 客观的。负责任的研究行为和增强方法的指导计划 还提供了再现性。