Northwestern University Allergy and Immunology Research (NUAIR) Program

西北大学过敏与免疫学研究 (NUAIR) 项目

• 批准号: 10207416
• 负责人: Bruce S Bochner
• 金额: $ 31.15万
• 依托单位: NORTHWESTERN UNIVERSITY AT CHICAGO
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-15 至 2025-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10207416
• 关键词: Hypersensitivity; Immunology; Research; Universities; programs

PROJECT SUMMARY/ABSTRACT The overall aim of the Northwestern University Allergy-Immunology Research (NUAIR) Program is to train postdoctoral scientists in translational research, here defined as research of disease mechanisms that includes investigations in human subjects or human samples. The NUAIR Program builds on our Allergy-Immunology Fellowship, which has a long history of excellence in clinical and academic training. Unified efforts of established investigators in our Division with those from other Divisions and Departments have created a rich environment for translational research in the NUAIR program in which clinical and basic researchers, both faculty and trainees, collaborate and interact in weekly research and didactic activities. These collaborations have led to multidisciplinary translational research programs in several allergic diseases supported by well-equipped laboratories and a large number of research cores and facilities. Under the NUAIR Program, a steady state of 4 MD, MD/PhD and/or PhD postgraduate trainees per year will receive 2 years of research training. Each will work together with a clinical research mentor and a basic research mentor to study mechanisms of allergic and immunological diseases, including studies of human subjects or their derived samples. In addition to well- structured research training and didactic activities, strong mentoring and close monitoring of trainees’ performances based on milestones will ensure proper progress during training. During the duration of funding, we have mentored 17 trainees; all but one of the 14 who have finished have academic or research positions. Our retention plan includes support for select trainees who remain in our Division as junior faculty members after T32-supported training, while they seek external funding support. Senior faculty members in the Allergy- Immunology Division have a strong record of mentoring NUAIR trainees towards obtaining K awards (6 so far) and new R grants (1 junior faculty). We also offer programs to inspire medical students and residents to pursue careers in Allergy-Immunology. Taken together, our rapidly expanding and comprehensive Allergy-Immunology research environment provides state-of-the-art training to highly qualified MD, MD/PhD and PhD postdoctoral trainees. These trainees will conduct collaborative translational research in Allergy-Immunology, initiating research careers that will help solve a severe national need for academic leaders in this field.

项目摘要/摘要 西北大学过敏 - 免疫学研究（NUAIR）计划的总体目的是培训 翻译研究的博士后科学家，在这里定义为包括疾病机制的研究 对人类受试者或人类样本进行研究。 Nuair计划建立在我们的过敏性免疫学上 奖学金，在临床和学术培训方面拥有悠久的卓越历史。统一的努力 我们部门的调查人员与其他部门和部门的调查员创造了丰富的环境 对于Nuair计划的翻译研究，临床和基础研究人员，包括教师和受训者 在每周的研究和教学活动中进行协作和互动。这些合作导致 设备齐全的多种过敏性疾病中的多学科翻译研究计划 实验室以及大量的研究核心和设施。根据Nuair计划，稳定状态为4 医学博士，医学博士/博士学位和/或博士研究生学员每年将接受2年的研究培训。每个都可以工作 以及临床研究的心理和基础研究心理，以研究过敏和 免疫疾病，包括对人类受试者或其衍生样本的研究。除了 结构化研究培训和教学活动，强烈的心理和对学员的密切监测 基于里程碑的表演将确保在培训期间进行适当的进步。在资金期间， 我们指导了17名学员；除了完成的14个外，所有人都有学术或研究职位。 我们的保留计划包括对在我们部门担任初级教职员工的精选培训的支持 T32支持的培训，他们寻求外部资金支持。过敏的高级教师 免疫学部门有着良好的心理Nuair学员的记录，以获得K奖项（到目前为止6个） 和新的R赠款（1名初级教师）。我们还提供计划，以激发医学生和居民购买 过敏 - 免疫学的职业。综上 研究环境为高素质的医学博士，医学博士/博士和博士博士提供了最先进的培训 学员。这些受训者将在过敏 - 免疫学上进行合作转化研究，启动 研究职业将有助于解决该领域的学术领导者的严重国家需求。