Northwestern University Allergy and Immunology Research (NUAIR) Program

项目概要/摘要 西北大学过敏-免疫学研究 (NUAIR) 项目的总体目标是培养 转化研究领域的博士后科学家，这里定义为疾病机制的研究，包括 对人类受试者或人类样本的研究。 NUAIR 计划建立在我们的过敏免疫学基础上 Fellowship 在临床和学术培训方面有着悠久的卓越历史。成立的统一努力 我司与其他司、部门的调查人员共同创造了一个丰富的环境 NUAIR 项目中的转化研究，其中临床和基础研究人员，包括教师和实习生， 在每周的研究和教学活动中进行协作和互动。这些合作导致 在设备精良的支持下，针对多种过敏性疾病的多学科转化研究项目 实验室和大量的研究核心和设施。根据 NUAIR 计划，稳定状态为 4 MD、MD/PhD 和/或博士研究生学员每年将接受 2 年的研究培训。每个都会起作用 与临床研究导师和基础研究导师一起研究过敏和过敏的机制 免疫疾病，包括对人类受试者或其衍生样本的研究。除了良好的 结构化的研究培训和教学活动，强有力的指导和对学员的密切监控 基于里程碑的表现将确保培训期间的适当进展。在资助期间， 我们已经指导了17名学员；已完成学业的 14 人中，除一名外，其他人都拥有学术或研究职位。 我们的保留计划包括对在毕业后留在我们部门作为初级教员的精选学员提供支持 T32支持培训，同时他们寻求外部资金支持。过敏症领域的高级教师- 免疫学部门在指导 NUAIR 学员获得 K 奖方面拥有良好的记录（迄今为止已有 6 项） 和新的 R 补助金（1 名初级教师）。我们还提供计划来激励医学生和住院医师追求 过敏免疫学的职业。总而言之，我们迅速扩展和全面的过敏免疫学 研究环境为高素质的医学博士、医学博士/博士和博士后提供最先进的培训 实习生。这些学员将进行过敏-免疫学方面的合作转化研究，启动 研究职业将有助于解决国家对该领域学术领袖的严峻需求。

PROJECT SUMMARY/ABSTRACT The overall aim of the Northwestern University Allergy-Immunology Research (NUAIR) Program is to train postdoctoral scientists in translational research, here defined as research of disease mechanisms that includes investigations in human subjects or human samples. The NUAIR Program builds on our Allergy-Immunology Fellowship, which has a long history of excellence in clinical and academic training. Unified efforts of established investigators in our Division with those from other Divisions and Departments have created a rich environment for translational research in the NUAIR program in which clinical and basic researchers, both faculty and trainees, collaborate and interact in weekly research and didactic activities. These collaborations have led to multidisciplinary translational research programs in several allergic diseases supported by well-equipped laboratories and a large number of research cores and facilities. Under the NUAIR Program, a steady state of 4 MD, MD/PhD and/or PhD postgraduate trainees per year will receive 2 years of research training. Each will work together with a clinical research mentor and a basic research mentor to study mechanisms of allergic and immunological diseases, including studies of human subjects or their derived samples. In addition to well- structured research training and didactic activities, strong mentoring and close monitoring of trainees’ performances based on milestones will ensure proper progress during training. During the duration of funding, we have mentored 17 trainees; all but one of the 14 who have finished have academic or research positions. Our retention plan includes support for select trainees who remain in our Division as junior faculty members after T32-supported training, while they seek external funding support. Senior faculty members in the Allergy- Immunology Division have a strong record of mentoring NUAIR trainees towards obtaining K awards (6 so far) and new R grants (1 junior faculty). We also offer programs to inspire medical students and residents to pursue careers in Allergy-Immunology. Taken together, our rapidly expanding and comprehensive Allergy-Immunology research environment provides state-of-the-art training to highly qualified MD, MD/PhD and PhD postdoctoral trainees. These trainees will conduct collaborative translational research in Allergy-Immunology, initiating research careers that will help solve a severe national need for academic leaders in this field.