Northwestern University Allergy and Immunology Research (NUAIR) Program

项目概要/摘要 西北大学过敏免疫学研究（NUAIR）计划的总体目标是培养 博士后科学家在转化研究，这里定义为疾病机制的研究，包括 人类受试者或人类样本的研究。NUAIR计划建立在我们的过敏免疫学基础上 奖学金，这在临床和学术培训方面有着悠久的历史。联合努力， 本科的调查人员与其他科和部门的调查人员一起，创造了一个丰富的环境， 在NUAIR程序中，临床和基础研究人员，教师和学员的转化研究， 在每周的研究和教学活动中进行协作和互动。这些合作导致了 在几种过敏性疾病的多学科转化研究计划，由装备精良的 实验室和大量的研究核心和设施。根据NUAIR计划，稳定状态为4 MD，MD/PhD和/或PhD研究生每年将接受2年的研究培训。每一个都将工作 与临床研究导师和基础研究导师一起研究过敏和 免疫性疾病，包括人类受试者或其衍生样品的研究。除了好- 结构化的研究培训和教学活动，强有力的指导和密切监测受训者的 基于里程碑的表现将确保培训期间的适当进展。在资助期间， 我们已辅导了17名受训人员;在14名已完成培训的学员中，除一人外，其余均担任学术或研究职位。 我们的保留计划包括支持选定的学员，他们在完成培训后仍留在我们部门担任初级教师 T32支持的培训，同时他们寻求外部资金支持。过敏症的高级教员- 免疫学部门在指导NUAIR学员获得K奖方面有着良好的记录（迄今为止有6个） 和新的R赠款（1初级教师）。我们还提供计划，以激励医学生和居民追求 过敏免疫学的职业总之，我们迅速扩大和全面的过敏免疫学 研究环境为高素质的MD，MD/PhD和PhD博士后提供最先进的培训 实习生这些学员将在过敏-免疫学方面进行合作转化研究， 研究事业，这将有助于解决一个严重的国家需要在这一领域的学术领袖。

PROJECT SUMMARY/ABSTRACT The overall aim of the Northwestern University Allergy-Immunology Research (NUAIR) Program is to train postdoctoral scientists in translational research, here defined as research of disease mechanisms that includes investigations in human subjects or human samples. The NUAIR Program builds on our Allergy-Immunology Fellowship, which has a long history of excellence in clinical and academic training. Unified efforts of established investigators in our Division with those from other Divisions and Departments have created a rich environment for translational research in the NUAIR program in which clinical and basic researchers, both faculty and trainees, collaborate and interact in weekly research and didactic activities. These collaborations have led to multidisciplinary translational research programs in several allergic diseases supported by well-equipped laboratories and a large number of research cores and facilities. Under the NUAIR Program, a steady state of 4 MD, MD/PhD and/or PhD postgraduate trainees per year will receive 2 years of research training. Each will work together with a clinical research mentor and a basic research mentor to study mechanisms of allergic and immunological diseases, including studies of human subjects or their derived samples. In addition to well- structured research training and didactic activities, strong mentoring and close monitoring of trainees’ performances based on milestones will ensure proper progress during training. During the duration of funding, we have mentored 17 trainees; all but one of the 14 who have finished have academic or research positions. Our retention plan includes support for select trainees who remain in our Division as junior faculty members after T32-supported training, while they seek external funding support. Senior faculty members in the Allergy- Immunology Division have a strong record of mentoring NUAIR trainees towards obtaining K awards (6 so far) and new R grants (1 junior faculty). We also offer programs to inspire medical students and residents to pursue careers in Allergy-Immunology. Taken together, our rapidly expanding and comprehensive Allergy-Immunology research environment provides state-of-the-art training to highly qualified MD, MD/PhD and PhD postdoctoral trainees. These trainees will conduct collaborative translational research in Allergy-Immunology, initiating research careers that will help solve a severe national need for academic leaders in this field.