Northwestern University Allergy and Immunology Research (NUAIR) Program

项目摘要/摘要 西北大学过敏免疫学研究项目的总体目标是培训 从事翻译研究的博士后科学家，在这里定义为研究疾病机制，包括 对人体受试者或人体样本的调查。NUAIR计划建立在我们的过敏免疫学基础上 联谊会，在临床和学术培训方面有着悠久的卓越历史。老牌企业的统一努力 我司和其他科室的调查人员创造了丰富的环境 在NUAIR项目中，临床和基础研究人员，包括教员和实习生， 在每周的研究和教学活动中进行协作和互动。这些合作导致了 设备齐全的几种过敏性疾病的多学科转换研究计划 实验室和大量的研究中心和设施。在Nuair计划下，稳定状态为4 每年的医学博士、医学博士和/或博士研究生实习生将接受两年的研究培训。每一个都会起作用 与一名临床研究导师和一名基础研究导师一起研究过敏和 免疫学疾病，包括对人类受试者或其衍生样本的研究。除了油井- 有组织的研究培训和教学活动，强有力的指导和对受训者的密切监测 基于里程碑的表现将确保在培训期间取得适当的进步。在资助期间， 我们已经指导了17名学员；除了一名学员外，其他14名学员都担任过学术或研究职位。 我们的留任计划包括支持选定的实习生在毕业后作为初级教员留在我们部门 T32支持的培训，同时寻求外部资金支持。过敏系的资深教员- 免疫学部在指导学员获得K奖方面有很好的记录(到目前为止有6个) 和新的R补助金(1名初级教员)。我们还提供项目，以激励医学生和住院医生 过敏免疫学方面的职业。综上所述，我们迅速发展和全面的过敏免疫学 研究环境为高素质的医学博士、医学博士和博士后提供最先进的培训 实习生。这些学员将在过敏免疫学方面进行合作翻译研究，启动 这将有助于解决国家对这一领域学术领袖的迫切需求。

PROJECT SUMMARY/ABSTRACT The overall aim of the Northwestern University Allergy-Immunology Research (NUAIR) Program is to train postdoctoral scientists in translational research, here defined as research of disease mechanisms that includes investigations in human subjects or human samples. The NUAIR Program builds on our Allergy-Immunology Fellowship, which has a long history of excellence in clinical and academic training. Unified efforts of established investigators in our Division with those from other Divisions and Departments have created a rich environment for translational research in the NUAIR program in which clinical and basic researchers, both faculty and trainees, collaborate and interact in weekly research and didactic activities. These collaborations have led to multidisciplinary translational research programs in several allergic diseases supported by well-equipped laboratories and a large number of research cores and facilities. Under the NUAIR Program, a steady state of 4 MD, MD/PhD and/or PhD postgraduate trainees per year will receive 2 years of research training. Each will work together with a clinical research mentor and a basic research mentor to study mechanisms of allergic and immunological diseases, including studies of human subjects or their derived samples. In addition to well- structured research training and didactic activities, strong mentoring and close monitoring of trainees’ performances based on milestones will ensure proper progress during training. During the duration of funding, we have mentored 17 trainees; all but one of the 14 who have finished have academic or research positions. Our retention plan includes support for select trainees who remain in our Division as junior faculty members after T32-supported training, while they seek external funding support. Senior faculty members in the Allergy- Immunology Division have a strong record of mentoring NUAIR trainees towards obtaining K awards (6 so far) and new R grants (1 junior faculty). We also offer programs to inspire medical students and residents to pursue careers in Allergy-Immunology. Taken together, our rapidly expanding and comprehensive Allergy-Immunology research environment provides state-of-the-art training to highly qualified MD, MD/PhD and PhD postdoctoral trainees. These trainees will conduct collaborative translational research in Allergy-Immunology, initiating research careers that will help solve a severe national need for academic leaders in this field.