Program Development (Pilot) Core

摘要-计划开发(试点)核心-核心B 约翰霍普金斯阿尔茨海默病经济学与服务中心(HEADS)项目的目标 发展(试点)的核心是培养高影响力的试点研究，以满足中心的总体目标。这个 Pilot Core将负责征集、审查、资助和支持成功执行 开发更大规模的验证性研究所需的小规模创新研究项目 解决与中心主题相关的知识方面的严重差距。Pilot Core将利用整个头部 中心研究环境，以确保试点PI充分参与中心社区，从而 传播调查结果是为了最大限度地发挥影响，以及指导和定制数据和计算需求 都得到了满足和支持。拟议的Heads Center试点研究将解决理论驱动的分析，以 生成和/或测试假设，或进行探索性研究，以开发和测试新方法。特定目标 1.执行结构化流程，以征集、审查和资助有前景的小规模和创新研究 识别、量化和应对ADRD带来的挑战的项目，这些项目与Heads Center保持一致 研究主题。具体目标2.为支持成功执行资助的试点研究，a)提供 监督和个性化支持(例如，项目管理、预算编制、数据安全、应急 规划)最大限度地严格和及时完成试点研究；以及b)确保试点绩效指标相互连接 到研发和数据核心，并整合到整个中心。试点核心将有助于总体 校长中心通过促进教师发展-初级教师和高级教师都寻求 新的研究方向符合我们的主题；培养新的和高影响力的研究；并为 整个中心科学界的负责人。拟议的公元01年试点计划将审查(1)承诺 利用在常规临床护理期间从电子健康记录中收集的新数据来识别老年人 成人ADRD(Kharrazi)；(2)ADRD在寻求帮助和服务使用方面的照顾方面存在种族差异 (3)与ADRD相关的财务损失的发生率和规模(Nicholas)；以及(4) 为参加传统按服务收费的医疗保险的ADRD老年患者开出处方模式 与Medicare Advantage Managed Care(Drabo)相比。

Abstract – Program Development (Pilot) Core – Core B The goal of the Johns Hopkins’ Economics of Alzheimer’s Disease & Services (HEADS) Center Program Development (Pilot) Core is to cultivate high-impact Pilot studies that address the Center’s overall aims. The Pilot Core will be responsible for soliciting, reviewing, funding, and supporting the successful execution of small-scale innovative research projects that are needed to develop larger-scale and confirmatory studies that address critical gaps in knowledge related to Center Themes. The Pilot Core will leverage the entire HEADS Center research environment to ensure that Pilot PIs are fully engaged in the Center community such that findings are disseminated to maximize impact, and that mentorship and tailored data and computing needs are met and supported. Proposed HEADS Center Pilot studies will either address theory-driven analyses to generate and/or test hypotheses or be exploratory studies to develop and test new methods. SPECIFIC AIM 1. To execute a structured process to solicit, review, and fund promising small scale and innovative research projects that identify, quantify, and address challenges posed by ADRD that are aligned with HEADS Center research themes. SPECIFIC AIM 2. To support successful execution of funded Pilot studies by a) providing oversight and individualized support (e.g., project management, budgeting, data security, contingency planning) to maximize the rigor and timely completion of Pilot studies; and b) ensuring Pilot PIs are connected to R&D and Data Cores and integrated within the overall Center. The Pilot Core will contribute to the overall HEADS Center through promoting faculty development – both of junior faculty and of senior faculty seeking a new research direction in line with our themes; cultivating novel and high-impact studies; and contributing to the overall HEADS Center scientific community. Proposed Year 01 Pilots will examine (1) the promise of leveraging novel data collected during routine clinical care from the Electronic Health Record to identify older adults with ADRD (Kharrazi); (2) race-based disparities in ADRD caregiving in help-seeking and service use (Fabius); (3) the prevalence and magnitude of ADRD-related financial loss (Nicholas); and (4) differences in prescribing patterns for older adults with ADRD who are enrolled in traditional fee-for-service Medicare as compared with Medicare Advantage managed care (Drabo).