Program Development (Pilot) Core

摘要-程序开发（试点）核心-核心B 约翰·霍普金斯大学阿尔茨海默病经济学与服务（HEADS）中心项目的目标 发展（试点）核心是培养高影响力的试点研究，解决中心的总体目标。的 Pilot Core将负责征集、审查、资助和支持以下项目的成功执行： 小规模的创新研究项目，需要开发更大规模的验证性研究， 解决与中心主题相关的知识的关键差距。试点核心将利用整个HEADS 中心研究环境，以确保试点PI充分参与中心社区， 传播调查结果，以最大限度地发挥影响， 得到满足和支持。拟议的HEADS中心试点研究将解决理论驱动的分析， 生成和/或测试假设或进行探索性研究以开发和测试新方法。具体目标 1.执行一个结构化的过程，以征求，审查和资助有前途的小规模和创新研究 确定、量化和解决ADRD带来的挑战的项目，这些项目与HEADS中心保持一致 研究主题。具体目标2.通过以下方式支持成功实施受资助的试点研究：a）提供 监督和个性化支持（例如，项目管理、预算、数据安全、应急 规划），以最大限度地提高试点研究的严谨性和及时完成;以及B）确保试点PI的连接 到研发和数据核心，并集成在整个中心内。试点核心将有助于整体 HEADS中心通过促进教师发展-无论是初级教师和高级教师寻求一个 新的研究方向符合我们的主题;培养新颖和高影响力的研究;并有助于 整个HEADS中心的科学界。拟议的01年试点将审查（1）承诺 利用电子健康记录中常规临床护理期间收集的新数据， 成人ADRD（Kharrazi）;（2）ADRD在寻求帮助和使用服务方面的种族差异 （Fabius）;（3）ADRD相关经济损失的患病率和程度（Nicholas）;（4） 为参加传统的按服务收费医疗保险的ADRD老年人开处方模式， 与Medicare Advantage Managed Care（Drabo）相比，

Abstract – Program Development (Pilot) Core – Core B The goal of the Johns Hopkins’ Economics of Alzheimer’s Disease & Services (HEADS) Center Program Development (Pilot) Core is to cultivate high-impact Pilot studies that address the Center’s overall aims. The Pilot Core will be responsible for soliciting, reviewing, funding, and supporting the successful execution of small-scale innovative research projects that are needed to develop larger-scale and confirmatory studies that address critical gaps in knowledge related to Center Themes. The Pilot Core will leverage the entire HEADS Center research environment to ensure that Pilot PIs are fully engaged in the Center community such that findings are disseminated to maximize impact, and that mentorship and tailored data and computing needs are met and supported. Proposed HEADS Center Pilot studies will either address theory-driven analyses to generate and/or test hypotheses or be exploratory studies to develop and test new methods. SPECIFIC AIM 1. To execute a structured process to solicit, review, and fund promising small scale and innovative research projects that identify, quantify, and address challenges posed by ADRD that are aligned with HEADS Center research themes. SPECIFIC AIM 2. To support successful execution of funded Pilot studies by a) providing oversight and individualized support (e.g., project management, budgeting, data security, contingency planning) to maximize the rigor and timely completion of Pilot studies; and b) ensuring Pilot PIs are connected to R&D and Data Cores and integrated within the overall Center. The Pilot Core will contribute to the overall HEADS Center through promoting faculty development – both of junior faculty and of senior faculty seeking a new research direction in line with our themes; cultivating novel and high-impact studies; and contributing to the overall HEADS Center scientific community. Proposed Year 01 Pilots will examine (1) the promise of leveraging novel data collected during routine clinical care from the Electronic Health Record to identify older adults with ADRD (Kharrazi); (2) race-based disparities in ADRD caregiving in help-seeking and service use (Fabius); (3) the prevalence and magnitude of ADRD-related financial loss (Nicholas); and (4) differences in prescribing patterns for older adults with ADRD who are enrolled in traditional fee-for-service Medicare as compared with Medicare Advantage managed care (Drabo).