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Adolescent Physiological and Emotional Stress Reactivity and Substance Use

青少年生理和情绪压力反应和物质使用

基本信息

批准号：
10226078
负责人：
Danny Rahal
金额：
$ 2.7万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
2020
资助国家：
美国
起止时间：
2020-08-01 至 2022-02-28
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10226078
关键词：
Address Adolescence Adolescent Adult Affect Affective Age Arousal Autonomic nervous system Biofeedback Biological Process Biology Data Data Set Development Distress Emotional Stress Exposure to Family Study Family health status Female Future Health High Prevalence Impairment Impulsivity Intervention Link Male Adolescents Measures Mediating Mental Health Mexican Americans Mission Moods National Institute of Drug Abuse Parasympathetic Nervous System Pattern Physiological Population Predisposition Psychological Stress Psychophysiology Reporting Research Research Personnel Risk Sampling Sex Differences Shapes Signal Transduction Social Processes Stress Substance Use Disorder Sympathetic Nervous System Symptoms System Testing Time Training Work Youth adolescent substance use biological adaptation to stress coping diaries emotion regulation ethnic diversity experience high risk indexing insight male negative affect prospective psychobiologic psychologic reduced substance use response sex skills social engagement social stress statistics stress reactivity stressor substance use theories therapy development trait

项目摘要

Project Summary/Abstract Psychophysiological responses to stress may provide a means for identifying youth at high risk for substance use. The sympathetic nervous system (SNS) and parasympathetic nervous system (PNS)—the two branches of the autonomic nervous system—are two ideal physiological systems. They are both sensitive to social stress and reliably related to psychological constructs related to substance use: impulsivity and emotion regulation, respectively. Moreover, blunted SNS and PNS reactivity have been linked with poorer mental health in youth and greater substance use in adults. However, limited work has examined how stress reactivity relates to substance use during adolescence, which is especially critical given that substance use increases during this time and early substance use can increase risk for substance use disorders. This proposal aims to address this gap by analyzing how SNS and PNS reactivity to stress relate to substance use in adolescence using two data sets. First, in the CHAMACOS dataset, links will be tested between SNS and PNS reactivity—as well as cross- system profiles of responses—at age 14 and substance use at age 14 and 16. This analysis provides a robust test of utility of these physiological responses for identifying concurrent and prospective substance use during a period when substance use is rapidly increasing. Then, links between substance use and both physiological and affective reactivity to stress will be tested in the Study of Family Health. In addition to completing the stress paradigm, adolescents reported their mood and stressors experienced for 14 days through daily diaries. PNS reactivity may relate to substance use because PNS activity indexes capacity for emotion regulation, and poor emotion regulation can increase proclivity for substance use. This aim will assess how physiological responses to a validated stressor and psychological responses to ecological stressors relate to substance use and thereby provide insight regarding why physiological responses relate to substance use. Finally, sex differences in links between substance use and stress responses will be assessed in both datasets. Researchers have hypothesized that impulsivity and emotion regulation—and, by extension, their physiological correlates—relate to substance use differently in males and females. Results will further clarify whether sex influences adolescent substance use and whether interventions should be tailored differently for males and females. Taken together, findings from this proposal will assess the utility of SNS and PNS reactivity for concurrent (Aims 1 and 2) and prospective substance use (Aim 1), interrogate the psychological means by which PNS reactivity may relate to substance use (Aim 2), and explore sex differences in these patterns (Aim 3). This information can be used for identification of youth at higher risk for substance use, developing interventions (e.g., targeting biofeedback, emotion regulation), and tailoring these interventions to males and females. Moreover, they build on pre- existing hypotheses regarding sex differences in substance use and utilize a developmental perspective to extend present findings to adolescence, a period when this work can be especially impactful for health.

项目总结/文摘

项目成果

期刊论文数量（12）

专著数量（0）

科研奖励数量（0）

会议论文数量（0）

专利数量（0）

Dampened psychobiological responses to stress and substance use in adolescence.

青春期对压力和物质使用的心理生物学反应受到抑制。

DOI：
10.1017/s0954579422000244
发表时间：
2023
期刊：
Development and psychopathology
影响因子：
3.3
作者：
Rahal,Danny;Shirtcliff,ElizabethA;Fuligni,Andrew;Kogut,Katherine;Gonzales,Nancy;Johnson,Megan;Eskenazi,Brenda;Deardorff,Julianna
通讯作者：
Deardorff,Julianna

Racial discrimination moderates associations between sociopolitical discussions and internalizing problems among racially minoritized college students.

种族歧视调节了少数族裔大学生的社会政治讨论与内化问题之间的联系。

DOI：
10.1037/cdp0000608
发表时间：
2023
期刊：
Cultural diversity & ethnic minority psychology
影响因子：
3.3
作者：
Rahal,Danny;Singh,ArmaanG
通讯作者：
Singh,ArmaanG

Achieving Status and Reducing Loneliness during the Transition to College: The Role of Entitlement, Intrasexual Competitiveness, and Dominance.

DOI：
10.1111/sode.12569
发表时间：
2022-08
期刊：
SOCIAL DEVELOPMENT
影响因子：
2
作者：
Rahal, Danny;Fales, Melissa R.;Haselton, Martie G.;Slavich, George M.;Robles, Theodore F.
通讯作者：
Robles, Theodore F.

Dampened autonomic nervous system responses to stress and substance use in adolescence.

青春期自主神经系统对压力和物质使用的反应受到抑制。

DOI：
10.1002/smi.3173
发表时间：
2023
期刊：
Stress and health : journal of the International Society for the Investigation of Stress
影响因子：
0
作者：
Rahal,Danny;Alkon,Abbey;Shirtcliff,Elizabeth;Gonzales,Nancy;Fuligni,Andrew;Eskenazi,Brenda;Deardorff,Julianna
通讯作者：
Deardorff,Julianna

Ethnic Identity in Arab Americans: Gender, Religious Upbringing, and Age Differences.