Administrative Core

行政核心摘要 行政核心将在第一阶段Cobre取得压倒性成功的基础上，继续提供 对该中心各方面的监督。这一核心的主要重点是继续提高研究质量 以及目标教员在膳食补充剂和炎症领域的生产力，因此他们将 成功争取独立的、主要的外部资金，如NIH R01赠款。在科布雷期间 第一阶段，第六阶段，我们的初级教员成功“毕业”。此外，我们还确保了P01/PPG中心的安全 涉及3名毕业于科布雷大学的初级教员。因此，第一阶段管理核心具有 在监督教员的成功和确保科布雷的可持续性方面发挥了重要作用。具体的 行政核心在第二阶段的目标如下： 1)促进对目标教员的指导，加强研究资源的使用，并使过渡成为可能 将目标教员转变为独立的、资金充足的调查人员。核心将负责组织 通过有效的辅导计划，促进初级侦查员的科学活动。会的 组织内部咨询委员会和外部咨询委员会的会议， 在评估目标学院和飞行员的研究进展时，向中心主任提供意见 项目和研究核心。 2)招聘5名新的终身教职初级教员，并为他们提供资金，以启动饮食研究 补充剂和炎症。核心将再招聘5名终身教职助理教授 4个不同学院在这一领域的膳食补充剂和炎症进一步拓展多学科 研究。将特别考虑吸引妇女和代表性不足的少数群体 也是我们第一阶段拨款的标志。 3)提供监督和支持多学科、协作的饮食研究计划 补充剂和炎症：核心将监督日常管理 中心，并确保研究核心的发展，以满足当前和未来招聘到 科布雷。初级调查人员将被鼓励成为企业家，并竞争NIH的资金 SBIR/STTR赠款。为了支持科布雷研究，我们将申请额外的NIH P01拨款，机构 以及个人博士前和博士后培训补助金和职业发展奖。 总而言之，行政核心的总体目标是进一步加强研究基础设施 具体地说，在表观遗传学方面，招聘额外的初级教员以增加临界质量，建立可持续的多学科 学科中心，并确保初级教员成功地过渡到独立科学家。

Administrative Core Abstract The Administrative Core will build on the overwhelming success of Phase-1 COBRE by continuing to provide oversight on all aspects of the Center. The main focus of this Core is to continue to enhance the research quality and productivity of the Target faculty in the area of Dietary Supplements and Inflammation so that they will be successful in competing for independent, major extramural funding such as the NIH R01 grants. During COBRE Phase-1, 6 of our junior faculty ‘graduated’ successfully. Also, we were able to secure a P01/PPG Center involving 3 junior faculty who have graduated from the COBRE. Thus, the Phase-1 Administrative Core has been instrumental in overseeing the success of faculty and ensuring sustainability of the COBRE. The specific aims of the Administrative Core during Phase II are as follows: 1) To facilitate mentoring of target faculty, enhance use of research resources, and enable the transition of target faculty into independent, well-funded investigators. The Core will be responsible for organizing and promoting the scientific activities of the junior investigators through effective mentoring program. It will organize the Internal Advisory Committee (IAC) and External Advisory Committee (EAC) meetings that will provide input to the Center Director in assessment of research progress of the Target Faculty and Pilot Projects as well as Research Cores. 2) To recruit 5 new tenure-track junior faculty and provide them funds to initiate research on dietary supplements and inflammation. The Core will recruit an additional 5 tenure-track Assistant Professors at 4 different colleges in this area of Dietary Supplements and Inflammation to further expand multi-disciplinary research. Special consideration will be given to attracting women and underrepresented minorities which has also been a hallmark of our Phase I grant. 3) To provide oversight and sustain multi-disciplinary, collaborative research program in dietary supplements and inflammation: The Core will provide oversight in the day-to-day management of the Center and ensure that Research Cores evolve to meet the needs of current and future recruits to the COBRE. The junior investigators will be encouraged to be entrepreneurs and compete for NIH-funded SBIR/STTR grants. To sustain the COBRE research, we will apply for additional NIH P01 grants, institutional and individual pre- and post-doctoral training grants and career development awards. In summary, the overall objective of the Administrative Core is to further enhance the research infrastructure specifically in epigenetics, recruit additional junior faculty to increase the critical mass, build sustainable multi- disciplinary Center, and ensure successful transition of junior faculty into independent scientists.