Administrative Core

行政核心

• 批准号: 10227907
• 负责人: Prakash S Nagarkatti
• 金额: $ 53万
• 依托单位: UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-09-01 至 2023-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10227907
• 关键词: Advisory Committees; Area; Arts; Centers of Research Excellence; Core Facility; Development; Disease; Engineering; Ensure; Epigenetic Process; Extramural Activities; Faculty; Fostering; Funding; Future; Grant; Human Resources; Individual; Inflammation; Inflammatory; Intellectual Property; Interdisciplinary Study; International; Journals; K-Series Research Career Programs; Mentors; Mentorship; Monitor; Phase; Pilot Projects; Productivity; Program Research Project Grants; Public Health Schools; Reporting; Research; Research Activity; Research Infrastructure; Research Personnel; Resource Sharing; Resources; Rewards; Schools; Science; Scientist; Secure; Small Business Innovation Research Grant; Small Business Technology Transfer Research; South Carolina; Strategic Planning; Training; Underrepresented Minority; United States National Institutes of Health; Universities; Woman; Work; collaborative environment; college; dietary supplements; drug discovery; expectation; experience; innovation; interest; medical schools; meetings; mid-career faculty; multidisciplinary; post-doctoral training; pre-doctoral; professor; programs; recruit; success; tenure track

Administrative Core Abstract The Administrative Core will build on the overwhelming success of Phase-1 COBRE by continuing to provide oversight on all aspects of the Center. The main focus of this Core is to continue to enhance the research quality and productivity of the Target faculty in the area of Dietary Supplements and Inflammation so that they will be successful in competing for independent, major extramural funding such as the NIH R01 grants. During COBRE Phase-1, 6 of our junior faculty ‘graduated’ successfully. Also, we were able to secure a P01/PPG Center involving 3 junior faculty who have graduated from the COBRE. Thus, the Phase-1 Administrative Core has been instrumental in overseeing the success of faculty and ensuring sustainability of the COBRE. The specific aims of the Administrative Core during Phase II are as follows: 1) To facilitate mentoring of target faculty, enhance use of research resources, and enable the transition of target faculty into independent, well-funded investigators. The Core will be responsible for organizing and promoting the scientific activities of the junior investigators through effective mentoring program. It will organize the Internal Advisory Committee (IAC) and External Advisory Committee (EAC) meetings that will provide input to the Center Director in assessment of research progress of the Target Faculty and Pilot Projects as well as Research Cores. 2) To recruit 5 new tenure-track junior faculty and provide them funds to initiate research on dietary supplements and inflammation. The Core will recruit an additional 5 tenure-track Assistant Professors at 4 different colleges in this area of Dietary Supplements and Inflammation to further expand multi-disciplinary research. Special consideration will be given to attracting women and underrepresented minorities which has also been a hallmark of our Phase I grant. 3) To provide oversight and sustain multi-disciplinary, collaborative research program in dietary supplements and inflammation: The Core will provide oversight in the day-to-day management of the Center and ensure that Research Cores evolve to meet the needs of current and future recruits to the COBRE. The junior investigators will be encouraged to be entrepreneurs and compete for NIH-funded SBIR/STTR grants. To sustain the COBRE research, we will apply for additional NIH P01 grants, institutional and individual pre- and post-doctoral training grants and career development awards. In summary, the overall objective of the Administrative Core is to further enhance the research infrastructure specifically in epigenetics, recruit additional junior faculty to increase the critical mass, build sustainable multi- disciplinary Center, and ensure successful transition of junior faculty into independent scientists.

行政核心摘要 行政核心将在第一阶段 COBRE 取得巨大成功的基础上继续提供 对中心的各个方面进行监督。该核心的主要重点是继续提高研究质量 目标教师在膳食补充剂和炎症领域的生产力和生产力，以便他们能够 成功竞争独立的主要校外资金，例如 NIH R01 补助金。 COBRE期间 第一期6名初级教师顺利“毕业”。此外，我们还获得了 P01/PPG 中心 包括 3 名毕业于 COBRE 的初级教师。因此，第一阶段行政核心已 在监督教师的成功和确保 COBRE 的可持续性方面发挥了重要作用。具体的 第二阶段行政核心的目标如下： 1）促进目标教师的指导，加强研究资源的利用，并实现过渡 目标教师转变为独立的、资金充足的研究人员。核心将负责组织 通过有效的指导计划促进初级研究人员的科学活动。它将 组织内部咨询委员会（IAC）和外部咨询委员会（EAC）会议， 为中心主任评估目标教师和试点的研究进展提供意见 项目以及研究核心。 2) 招募 5 名新的终身教授并为他们提供资金以开展饮食研究 补充剂和炎症。核心将另外招募 5 名终身教授助理教授 膳食补充剂和炎症领域的 4 个不同学院进一步扩展多学科 研究。将特别考虑吸引妇女和代表性不足的少数群体 也是我们第一阶段资助的一个标志。 3) 提供监督并维持饮食领域的多学科合作研究计划 补充剂和炎症：核心将在日常管理中提供监督 中心并确保研究核心不断发展以满足当前和未来新员工的需求 科布雷。将鼓励初级研究者成为企业家并竞争 NIH 资助的项目 SBIR/STTR 赠款。为了维持 COBRE 研究，我们将申请额外的 NIH P01 拨款、机构资助 以及个人博士前和博士后培训补助金和职业发展奖。 总而言之，行政核心的总体目标是进一步加强研究基础设施 特别是在表观遗传学方面，招募更多的初级教师来增加临界质量，建立可持续的多学科 学科中心，并确保初级教师成功转型为独立科学家。