Administrative Core

行政核心摘要 行政核心将在COBRE第一阶段取得巨大成功的基础上，继续提供 监督中心的各个方面。该核心的主要重点是继续提高研究质量 和目标教师在膳食补充剂和炎症领域的生产力，使他们将 成功竞争独立的，主要的校外资金，如NIH R 01赠款。在COBRE期间 第一阶段，我们的初级教师6“毕业”成功。此外，我们能够确保P01/PPG中心 涉及3名从COBRE毕业的初级教师。因此，第一阶段的行政核心 一直在监督教师的成功，并确保COBRE的可持续性工具。具体 第二阶段行政核心的目标如下： 1)促进对目标教师的指导，加强研究资源的利用，并实现过渡 将目标教师转变为独立的资金充足的调查员核心将负责组织 并通过有效的指导计划促进初级研究人员的科学活动。它将 组织内部咨询委员会（IAC）和外部咨询委员会（EAC）会议， 为中心主任提供评估目标学院和试点研究进展的意见 项目以及研究核心。 2)招募5名新的终身制初级教师，并为他们提供资金，以启动饮食研究 补充剂和炎症。核心将招募额外的5个终身助理教授， 4个不同的学院在这方面的膳食补充剂和炎症，以进一步扩大多学科 research.将特别考虑吸引妇女和代表性不足的少数民族， 也是我们第一阶段资助的一个标志。 3)提供监督和维持多学科，合作研究计划，在饮食 补充剂和炎症：核心将在日常管理中提供监督， 集中并确保研究核心不断发展，以满足当前和未来招聘人员的需求， 眼镜蛇将鼓励初级研究人员成为企业家，并竞争NIH资助的 SBIR/STTR赠款。为了维持COBRE研究，我们将申请额外的NIH P01赠款， 以及个人博士前和博士后培训赠款和职业发展奖。 总的来说，行政核心的总体目标是进一步加强研究基础设施 特别是在表观遗传学，招聘额外的初级教师，以增加临界质量，建立可持续的多， 学科中心，并确保初级教师成功过渡到独立的科学家。

Administrative Core Abstract The Administrative Core will build on the overwhelming success of Phase-1 COBRE by continuing to provide oversight on all aspects of the Center. The main focus of this Core is to continue to enhance the research quality and productivity of the Target faculty in the area of Dietary Supplements and Inflammation so that they will be successful in competing for independent, major extramural funding such as the NIH R01 grants. During COBRE Phase-1, 6 of our junior faculty ‘graduated’ successfully. Also, we were able to secure a P01/PPG Center involving 3 junior faculty who have graduated from the COBRE. Thus, the Phase-1 Administrative Core has been instrumental in overseeing the success of faculty and ensuring sustainability of the COBRE. The specific aims of the Administrative Core during Phase II are as follows: 1) To facilitate mentoring of target faculty, enhance use of research resources, and enable the transition of target faculty into independent, well-funded investigators. The Core will be responsible for organizing and promoting the scientific activities of the junior investigators through effective mentoring program. It will organize the Internal Advisory Committee (IAC) and External Advisory Committee (EAC) meetings that will provide input to the Center Director in assessment of research progress of the Target Faculty and Pilot Projects as well as Research Cores. 2) To recruit 5 new tenure-track junior faculty and provide them funds to initiate research on dietary supplements and inflammation. The Core will recruit an additional 5 tenure-track Assistant Professors at 4 different colleges in this area of Dietary Supplements and Inflammation to further expand multi-disciplinary research. Special consideration will be given to attracting women and underrepresented minorities which has also been a hallmark of our Phase I grant. 3) To provide oversight and sustain multi-disciplinary, collaborative research program in dietary supplements and inflammation: The Core will provide oversight in the day-to-day management of the Center and ensure that Research Cores evolve to meet the needs of current and future recruits to the COBRE. The junior investigators will be encouraged to be entrepreneurs and compete for NIH-funded SBIR/STTR grants. To sustain the COBRE research, we will apply for additional NIH P01 grants, institutional and individual pre- and post-doctoral training grants and career development awards. In summary, the overall objective of the Administrative Core is to further enhance the research infrastructure specifically in epigenetics, recruit additional junior faculty to increase the critical mass, build sustainable multi- disciplinary Center, and ensure successful transition of junior faculty into independent scientists.