Administrative Core

项目摘要/摘要--行政核心 行政核心的总体目标是领导、协调和监督 加州大学旧金山分校风湿病中心的精准医学(P30)。在玛丽博士的指导下 Nakamura(PD)和Janoos Yazdany(助理PD)，行政核心是 有兴趣在风湿病方面进行高级精准医学研究的研究人员。这个 管理核心将直接与调查人员合作，将他们与Premier Core服务联系起来，并促进 临床医生为风湿病患者看病，基础研究人员开发切割-之间的新合作 边缘技术，以及能够整合复杂数据流进行分析的生物信息学专家。这个 行政核心将评估项目规划和生物检疫的需求，并安排适当的 咨询Premier核心1)临床和数据信息学(CDI)核心，2)基因组技术(GT) 3)综合生物信息学(IB)核心。 行政核心为所有Premier核心提供行政和财务监督 确保中心的平稳运行。行政核心协调成员资格、沟通 以及一项包括研讨会、培训讲习班、指导方案、试点赠款和 核心使用授权计划。Premier制造患者队列和生物标本，高级基因组 可通过我们的资源核心访问的技术和复杂的信息学服务，以及 协助制定复杂的实验计划。通过这种方式，我们将协作小组聚集在一起，可以推动 风湿病的创新性研究。通过培训、指导和资助机会，我们进一步 支持和鼓励青年研究人员将精准医学研究重点放在风湿病上。 管理核心创建了一个既支持Premier调查员又支持 资源核心。Premier的总体目标是促进创新研究和合作研究， 将导致对复杂风湿病的更好描述和有针对性的治疗。

PROJECT SUMMARY/ABSTRACT – Administrative Core The overall goal of the Administrative Core is to provide leadership, coordination and oversight for PREMIER, the Precision Medicine in Rheumatology Center (P30) at UCSF. Under the direction of Drs. Mary Nakamura (PD) and Jinoos Yazdany (Associate PD), the Administrative Core serves as an entry portal for researchers interested in pursuing advanced precision medicine studies in rheumatic diseases. The Administrative Core will work directly with investigators to link them with PREMIER Core services and facilitate new collaborations between clinicians seeing rheumatic disease patients, basic researchers developing cutting- edge technologies, and bioinformatics experts capable of integrating complex streams of data for analysis. The Administrative Core will assess needs for project planning and biospecimens and arrange appropriate consultation with PREMIER Cores 1) Clinical and Data Informatics (CDI) Core, 2) Genomic Technology (GT) Core, and 3) Integrative Bioinformatics (IB) Core. The Administrative Core provides administrative and financial oversight for all the PREMIER Cores and ensures the smooth operation of the Center. The Administrative Core coordinates membership, communications and an enrichment program involving seminars, training workshops, a mentoring program, a Pilot Grant and a Core Usage Grant program. PREMIER makes patient cohorts and biospecimens, advanced genomic technologies and complex informatics services accessible through our Resource Cores, along with services to assist with complex experimental planning. In this way we bring together collaborative groups that can advance innovative studies in rheumatic diseases. Through training, mentoring and funding opportunities we further support and encourage young investigators to focus their precision medicine research on rheumatic diseases. The Administrative Core creates an infrastructure that supports both PREMIER Investigators and the Resource Cores. The overall goal of PREMIER is to foster innovative research and collaborative studies that will lead to better delineation and targeted treatment of complex rheumatic disease.