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Administrative Core

行政核心

基本信息

批准号：
10281471
负责人：
Mary C Nakamura
金额：
$ 23.1万
依托单位：
UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-09-21 至 2026-08-31
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/10281471
关键词：
Basic Science Bioinformatics Cells Clinical Clinical Data Clinical Informatics Clinical Research Clinical Sciences Collaborations Collection Communication Communities Complex Consultations Data Analyses Databases Development Disease Educational workshop Ensure Fees Fostering Funding Funding Opportunities Genomics Goals Grant Individual Informatics Infrastructure Leadership Link Maintenance Mentors Newsletter Occupational activity of managing finances Patients Phenotype Preparation Progress Reports Records Reporting Research Research Design Research Personnel Resources Rheumatism Rheumatology Sampling Services Technology Training United States National Institutes of Health Universities Utilization Review Work autoimmune rheumatologic disease base biobank cohort data streams experience innovation interest investigator training meetings member new technology novel operation outreach precision medicine programs ranpirnase targeted treatment web site

项目摘要

PROJECT SUMMARY/ABSTRACT – Administrative Core The overall goal of the Administrative Core is to provide leadership, coordination and oversight for PREMIER, the Precision Medicine in Rheumatology Center (P30) at UCSF. Under the direction of Drs. Mary Nakamura (PD) and Jinoos Yazdany (Associate PD), the Administrative Core serves as an entry portal for researchers interested in pursuing advanced precision medicine studies in rheumatic diseases. The Administrative Core will work directly with investigators to link them with PREMIER Core services and facilitate new collaborations between clinicians seeing rheumatic disease patients, basic researchers developing cutting- edge technologies, and bioinformatics experts capable of integrating complex streams of data for analysis. The Administrative Core will assess needs for project planning and biospecimens and arrange appropriate consultation with PREMIER Cores 1) Clinical and Data Informatics (CDI) Core, 2) Genomic Technology (GT) Core, and 3) Integrative Bioinformatics (IB) Core. The Administrative Core provides administrative and financial oversight for all the PREMIER Cores and ensures the smooth operation of the Center. The Administrative Core coordinates membership, communications and an enrichment program involving seminars, training workshops, a mentoring program, a Pilot Grant and a Core Usage Grant program. PREMIER makes patient cohorts and biospecimens, advanced genomic technologies and complex informatics services accessible through our Resource Cores, along with services to assist with complex experimental planning. In this way we bring together collaborative groups that can advance innovative studies in rheumatic diseases. Through training, mentoring and funding opportunities we further support and encourage young investigators to focus their precision medicine research on rheumatic diseases. The Administrative Core creates an infrastructure that supports both PREMIER Investigators and the Resource Cores. The overall goal of PREMIER is to foster innovative research and collaborative studies that will lead to better delineation and targeted treatment of complex rheumatic disease.

项目概要/摘要-行政核心行政核心的总体目标是领导、协调和监督以下方面： PREMIER，加州大学旧金山分校流变学中心（P30）的精准医学。在玛丽医生的指导下中村（PD）和Jinoos Yazdany（副PD），行政核心作为入口门户，有兴趣在风湿性疾病中进行先进的精确医学研究的研究人员。的行政核心将直接与研究者合作，将他们与PREMIER核心服务联系起来，临床医生与风湿病患者、基础研究人员之间的新合作，边缘技术和生物信息学专家能够整合复杂的数据流进行分析。的行政核心将评估项目规划和生物标本的需求，并安排适当的咨询PREMIER核心1）临床和数据信息学（CDI）核心，2）基因组技术（GT）核心，和3）整合生物信息学（IB）核心。行政核心为所有主要核心提供行政和财务监督，确保中心的顺利运行。行政核心协调成员资格、通信和一个丰富的计划，包括研讨会，培训讲习班，辅导计划，试点赠款和核心使用补助计划。PREMIER使患者队列和生物标本，先进的基因组技术和复杂的信息服务，沿着服务，协助复杂的实验计划。通过这种方式，我们将能够进步的协作团体聚集在一起风湿性疾病的创新研究。通过培训、指导和资助机会，支持和鼓励年轻的研究人员将他们的精准医学研究集中在风湿性疾病上。管理核心创建了一个支持主要研究者和资源核心。PREMIER的总体目标是促进创新研究和合作研究，将导致更好的描绘和复杂风湿性疾病的靶向治疗。