Alterations and Renovations Project

生物医学信息学、生物信息学、临床研究和创新中心(BIB-CRI)摘要 这项拟议的改建/翻新(A&R)部分是大平原的IDEA临床和翻译 研究(GP IDEA-CTR)更新将创造生物医学信息学、生物信息学、临床 研究创新中心(BIB-CRI)。此次翻新旨在支持日益增长的 生物医学信息学和生物信息学及互动空间的GP IDEA-CTR网络迎接GP IDEA-CTR整体更新目标：1)发展基础设施、服务、资源和社区 扩展CTR所需的关系；2)扩展专业发展活动以培养成功 CTR调查人员；3)加强整个GP-IDEA网络的协作伙伴关系；以及4)创建 培育创新的多学科、多站点和跨实体(例如，公私合营)的环境 合伙企业。因此，A&R的具体目标是目标1：翻新Eppley科学馆的一层以 创建BIB-CRI中心以扩大计算机密集型工作的空间，目标2：更新基础设施 需要支持计算密集型研究，包括供暖、通风和空调 (暖通空调)、信息技术(IT)和构建安全系统，以及目标3：加强协作 在整个大平原的生物信息学和CTR团队内部和之间-IDEA-CTR，具有灵活的交互 空间，如‘挤在一起的房间’，计算团队吊舱，以及用于访问区域的着陆空间 研究人员。通过建设BIB-CRI枢纽，提升生物医学信息学(BIBCE)能力 以及生物统计(BERD)核心，以满足所有GP IDEA-CTR的信息学和数据分析需求 网络合作伙伴。艾普利科学馆(ESH)7楼的翻新提供7590平方英尺的净面积 可用于扩展生物信息学重点研究的空间。该空间位于UNMC的中心位置，将 为所有全科医生IDEA-CTR网络研究人员和临床医生之间的互动提供总部。围嘴- CRI集线器将提供更新的网络基础设施，以支持计算密集型分析和高 加快向异地超级计算机传输数据。计算吊舱将提供灵活的空间来支持 不同的团队规模和工作风格。会客室和其他互动空间将加强合作， 虽然专为访问GP IDEA-CTR的教职员工和学生提供的工作空间将增加协作和 促进指导和学习。这将增加传播新的工具和方法 所有GP IDEA-CTR网站的研究人员。通过这次翻修建造的专用BIB-CRI枢纽将 扩大计算分析的覆盖范围，增强计算基础设施和参与的空间 专业发展活动，加强所有全科医生IDEA-CTR合作伙伴的关系，促进 与DaCCoTA CTR建立协作伙伴关系，减少资源重复，促进多学科 合作，服务于NIH的目标，加强整个国家的生物医学研究和健康 我们所服务的社区。

Biomedical Informatics, Bioinformatics, Clinical Research and Innovation Hub (BIB-CRI) Summary This proposed alteration/renovation (A&R) component of the Great Plains IDeA Clinical and Translational Research (GP IDeA-CTR) renewal will create the Biomedical Informatics, Bioinformatics, Clinical Research and Innovation Hub (BIB-CRI). This renovation is designed to support the growing needs of biomedical informatics and bioinformatics and interaction space of the GP IDeA-CTR network to meet the GP IDeA-CTR Overall renewal aims: 1) develop the infrastructure, services, resources, and community relationships needed to expand CTR; 2) expand professional development activities to cultivate successful CTR investigators; 3) strengthen collaborative partnerships across GP-IDeA network; and 4) create an environment that fosters innovative multidisciplinary, multisite, and cross-entity (e.g., public-private) partnerships. Accordingly, the A&R specific aims are Aim 1: Renovate a floor of Eppley Science Hall to create the BIB-CRI Hub to expand space for computer-intensive work, Aim 2: Update the infrastructure needed to support computationally-intensive research, including heating, ventilation, and air-conditioning (HVAC), Informational Technology (IT), and building security systems, and Aim 3: Enhance collaborations within and among bioinformatics and CTR teams across the Great Plains-IDeA-CTR, with flexible interaction spaces, such as ‘huddle rooms’, computational team pods, and landing spaces for visiting regional researchers. By building the BIB-CRI hub, we will enhance the ability of the Biomedical Informatics (BIBCE) and the Biostatistics (BERD) Cores to serve informatics and data analytic needs across all GP IDeA-CTR network partners. The renovation of Eppley Science Hall (ESH) 7th floor provides 7,590 net-square-feet of useable space for expanding bioinformatics focused research. This space is centrally located at UNMC and will provide a headquarters for interactions among all GP IDeA-CTR network researchers and clinicians. The BIB- CRI hub will provide updated cyberinfrastructure to support computationally-intensive analyses and high- speed data transfer to off-site supercomputers. Computational pods will provide flexible space to support different team sizes and work-styles. Huddle rooms and other interaction spaces will enhance collaborations, while dedicated work spaces for visiting GP IDeA-CTR faculty and students will increase collaboration and facilitate mentoring and learning. This will increase the dissemination of new tools and approaches for researchers across all GP IDeA-CTR sites. The dedicated BIB-CRI hub built though this renovation will expand the footprint for computational analysis, enhance computational infrastructure and space to engage in professional development activities, strengthen relationships across all GP IDeA-CTR partners, boost collaborative partnerships with the DaCCoTA CTR, reduce duplication of resources, and foster multidisciplinary collaboration, in service of NIH objectives of enhancing improving biomedical research and health across the communities we serve.