Great Plains IDeA-CTR

 描述(申请人提供)：大平原是一个广袤的农村地区，有零星的城市发展。地理和社会隔离--再加上农村和服务不足的城市地区缺乏初级和专科医疗--是我们一些最脆弱人群的特征。我们的目标是开发一个强大的网络化研究基础设施，以培养、发展和指导我们的临床和转化性研究(CTR)研究人员，并在他们之间以及与大平原北部的社区成员之间建立合作。我们计划与其他IDEA-CTR实体建立伙伴关系，以分享发展CTR事业的最佳做法。随着我们努力更好地了解疾病的发展及其预防手段，特别是在我们的IDEA-CTR网络中与农村和城市服务不足的人群有关的情况下，这些努力将使我们在研究奖项方面变得更具竞争力。大平原IDEA-CTR将内布拉斯加州大学医学中心的资源与其合作伙伴的资源联系起来，这些合作伙伴从内布拉斯加州延伸到邻近的IDEA州、南达科他州和北达科他州，并与堪萨斯大学前沿CTSA合作，以实现四个总体目标：1)创建和维持扩大资助的CTR所需的基础设施、服务、资源和社区关系；2)培养一支具有全面专业发展计划、试点拨款、关键服务(KCA)和专业知识的成功CTR调查员队伍，他们准备开发和实施创新工具和方法，并领导CTR团队；3)与南达科他州、北达科他州和堪萨斯州的大平原IDEA-CTR州建立现有的合作伙伴关系，以扩大CTR团队，传播现有资源以提高其利用率和减少重复，合作建立新的计划和资源，并改善健康成果；4)实施全面的内部评估计划，以评估和加强大平原IDEA-CTR的领导地位，衡量大平原IDEA-CTR计划在该地区的影响，跟踪大平原IDEA-CTR在目标和绩效里程碑方面的进展，以及评估资源和在整个地区传播的有效性。

 DESCRIPTION (provided by applicant): The Great Plains is a vast, rural region with pockets of urban development. Geographic and social isolation- combined with lack of access to primary and specialized care in both rural and underserved urban areas- characterizes some of our most vulnerable populations Our objective is to develop a robust, networked research infrastructure to nurture, develop, and guide our clinical and translational research (CTR) investigators, as well as build collaborations among them and with community members across the northern Great Plains. We plan to foster partnerships with other IDeA-CTR entities in order to share best practices on developing CTR undertakings. Such efforts will position us to become more competitive for research awards as we strive to better understand the development of disease and the means for its prevention-particularly as it pertains to rural and urban underserved populations in our IDeA-CTR network. The Great Plains IDeA- CTR will link the resources of the University of Nebraska Medical Center to those of its partners that stretch from Nebraska, to its neighboring IDeA states, South Dakota and North Dakota, and in collaboration with the University of Kansas Frontiers CTSA, to achieve four overall goals: 1) Create and sustain the infrastructure, services, resources, and community relationships needed to expand funded CTR; 2) Develop a cadre of successful CTR investigators with a comprehensive professional development program, pilot grants, key services (KCAs), and expertise, who are prepared to develop and implement innovative tools and approaches and lead CTR teams; 3) Build upon existing partnerships with regional Great Plains IDeA-CTR states of South Dakota, North Dakota, and Kansas to expand CTR teams, disseminate existing resources to enhance their utilization and reduce duplication, collaborate to build new programs and resources, and improve health outcomes; 4) Implement a comprehensive internal evaluation program to assess and strengthen Great Plains IDeA-CTR leadership, measure the impact of the Great Plains IDeA-CTR programs in the region, track Great Plains IDeA-CTR progress on goals and performance milestones, and assess effectiveness of resources and dissemination across the region.