Durable Self-cleaning Fluorinated Graphene Oxide Coated N95 Respirators

耐用自清洁氟化氧化石墨烯涂层 N95 呼吸器

• 批准号: 10284378
• 负责人: Hui Zhao
• 金额: $ 18.83万
• 依托单位: UNIVERSITY OF NEVADA LAS VEGAS
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-09-30 至 2023-09-29
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10284378
• 关键词: Durable; Self; cleaning; Fluorinated; Graphene

Title: Durable Self-cleaning Fluorinated Graphene Oxide Coated N95 Respirators Abstract This project addresses the healthcare and social assistance/Immune, Infectious and Dermal Disease Prevention (HSAxIID) with the strategic goal 3: reduce occupational immune, infectious, and dermal disease. The intermediate goal is to prevent the infectious disease transmission with research focus on personal protection equipment (3.3.H). The coronavirus disease 2019 (COVID-19) pandemic is primarily transmitted by virus laden droplets and short-range aerosols. N95 respirator is an essential personal protection equipment to combat COVID-19. Due to concerns over virus accumulation on the respirator for fomite infection, it is crucial to make the respirators less contaminated as possible to better protect the healthcare workers. To address this critical challenge, this application proposes to spray-coat highly fluorinated graphene oxide onto the outer surface of the N95 respirator. Spray coating adds an additional porous nanostructure to the N95 respirator. The highly fluorinated graphene oxide nanostructured coating possesses the exceptional superhydrophobicity. The superhydrophobicity exhibits extreme water repellence and is hypothesized to make the N95 respirators less contaminated by repelling the respiratory droplets off the respirator’s surface instantaneously. In addition, the extraordinary robustness of graphene oxide to various environmental challenges is supposed to address the durability issue associated with frequently reusing. The specific aims are, therefore, to test the highly fluorinated graphene oxide nanostructured coating is (1) capable of repelling respiratory droplets while maintaining the aerosol filtration efficiency; (2) capable of preventing the accumulation of SARS-CoV-2 virus on the N95 respirators. The outputs of the project will be journal articles, reports, and conference proceedings and presentations. The intermediate outcomes will include citations in the literature and adoption of the technology developed in the project. The end outcomes will be better protection of healthcare workers in terms of preventing transmission of work-related infectious diseases among workers by translating this new technology to the healthcare & social assistance sector, addressing Research to Practice (r2p).

标题：耐用自清洁氟化氧化石墨烯涂层N95呼吸器 摘要 该项目涉及医疗保健和社会援助/免疫、传染病和皮肤病 预防（HSAxIID），战略目标3：减少职业免疫、传染和皮肤病。 中间目标是预防传染病传播，研究重点是个人 保护设备（3.3.H）。2019冠状病毒病（COVID-19）大流行主要通过以下途径传播： 携带病毒的飞沫和短程气溶胶。N95呼吸器是一种必备的个人防护装备， 抗击新冠肺炎由于担心呼吸器上的病毒积累会导致污染物感染， 使消毒器尽可能少受污染，以更好地保护医护人员。为了解决这个 关键挑战，该申请提出将高度氟化的氧化石墨烯喷涂到外表面上 N95呼吸器喷涂为N95呼吸器增加了额外的多孔纳米结构。高度 氟化氧化石墨烯纳米结构涂层具有优异的超疏水性。的 超疏水性表现出极端的拒水性，并假设使N95疏水剂更少 通过瞬间将呼吸道飞沫从呼吸器表面排斥出去而被污染。此外该 氧化石墨烯对各种环境挑战的非凡鲁棒性被认为解决了 与频繁重复使用相关的耐久性问题。因此，具体目标是测试高度氟化的 氧化石墨烯纳米结构涂层（1）能够排斥呼吸液滴，同时保持 气溶胶过滤效率;（2）能够防止SARS-CoV-2病毒在N95上的积累 冰箱。该项目的产出将是期刊文章、报告和会议记录， 介绍。中间结果将包括文献中的引用和技术的采用 在项目中开发。最终结果将是在预防方面更好地保护医护人员， 通过将这项新技术转化为 医疗保健和社会援助部门，解决从研究到实践的问题。