The 'Career MODE' Program: Careers through Mentoring and training in Omics and Data for Early-stage investigators

“职业模式”计划：通过为早期研究人员提供组学和数据方面的指导和培训来实现职业生涯

• 批准号: 10285137
• 负责人: Andrea Baccarelli
• 金额: $ 45.81万
• 依托单位: COLUMBIA UNIVERSITY HEALTH SCIENCES
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2026-07-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10285137
• 关键词: Address; Age; Applications Grants; Appointment; Biological Process; Biomedical Research; Clinical Medicine; Collaborations; Communication; Data; Data Analyses; Data Science; Development; Discipline; Doctor of Philosophy; Drops; Education; Educational Curriculum; Educational Materials; Educational process of instructing; Evaluation; Face; Faculty; Fostering; Funding; Future; Generations; Genomics; Goals; Grant; Grant Review; Health; Hybrids; Individual; Institution; Investments; Knowledge; Leadership; Mentors; Methods; National Institute of General Medical Sciences; Pathway interactions; Persons; Positioning Attribute; Postdoctoral Fellow; Qualitative Evaluations; Quantitative Evaluations; Reproducibility; Research; Research Personnel; Research Project Grants; Resources; Risk; Route; Science; Scientist; Secure; Social Sciences; Structure; Technology; Time; Training; Training Programs; Travel; United States; United States National Academy of Sciences; United States National Institutes of Health; Universities; Woman; Writing; career; career development; career networking; cohort; design; early-career faculty; empowered; exhaustion; experience; health equity; human disease; improved; instructor; interest; learning strategy; member; microbiome; multidimensional data; multidisciplinary; outreach; precision medicine; professor; programs; recruit; responsible research conduct; skill acquisition; skills; success; symposium; tenure track; tool; trend; virtual

PROJECT SUMMARY/ABSTRACT The National Academy of Sciences describes the barriers that scientists experience on the path from mentored to independent research as the single most critical threat to the future of biomedical sciences in the United States (US). Women and individuals from marginalized groups face steeper obstacles, particularly in technology-intensive fields such as omic sciences. Despite NIH’s separate grant reviews and paylines, the mean age at which investigators receive their first R01 has continued to climb to an all-time high of 46 years, extending a 35-year negative trend. In parallel, the likelihood of PhD graduates becoming professors has dropped significantly in the last decades, putting the future of biomedical research in the US at risk. To address these challenges, we propose the 'Career MODE' program: Careers through Mentoring and training in Omics and Data for Early-stage investigators to empower diverse cohorts of young researchers across the US—i.e., postdocs in the final years of mentored training and faculty members within two years of their first appointment—to establish independent, successful careers in omics and data sciences. Omics— ranging from genomics to the microbiome—have revolutionized biomedical sciences. As they have become part of any biomedical field, the scarcity of a workforce within each discipline with appropriate omic training has emerged as a critical challenge. We seek to develop an 11-month program to provide intensive training in omics and data science and specialized mentoring from a nationwide, diverse network of 70+ mentors. Career MODE will also feature training in professional skills, including leadership and team management, grant writing, mentoring, goal setting and strategy development, communication and teaching, scientific rigor, transparency, reproducibility, responsible conduct of research, and health equity. By leveraging its nationwide group of mentors and trainees, Career MODE will also offer a structured approach to enhance collaborations and networking, help create teams for breakthrough research projects and K99/R00 and R01-type grant proposals, further career development, and help secure tenure-track positions and faculty promotions. Career MODE will feature hybrid (virtual and in-person) coursework and learning activities (boot camps, roundtables, panels, symposia, observerships), a robust evaluation of each objective, and will generate and disseminate extensive educational material on omics and data science. The program will do outreach to the most promising, motivated, and diverse junior investigators—a group traditionally with limited resources— to create empowered cohorts of scientists to pursue independence through advanced knowledge and tools in omics and data sciences applicable to all biomedical research fields. Thus, our program aligns with NIGMS goals and provides a high return for investment. We will also develop strategies to advance equity and access in omics research and promote Career MODE to academic institutions, sponsors, and stakeholders to reach financial sustainability and self-support beyond the five years of R25 funding.

项目摘要/摘要 美国国家科学院描述了科学家在Mattered的道路上遇到的障碍 独立研究是对联合生物医学科学未来的最关键威胁 国家（美国）。边缘化群体的妇女和个人面临钢人的障碍，尤其是在 技术密集型科学等技术密集型领域。尽管NIH进行了单独的赠款评论和收费线，但 调查人员收到的第一个R01的平均年龄继续攀升至历史最高46年， 扩展了35年的负面趋势。同时，博士毕业生成为教授的可能性 在过去的几十年中，大幅下降，使美国生物医学研究的未来处于危险之中。 为了应对这些挑战，我们提出“职业模式”计划：通过指导和 对《 OMIC和数据培训》培训早期研究人员，以增强潜水员队列的能力 在美国的整个美国，在培训的最后几年和教职员工两年之内 他们的第一个任命 - 在OMIC和数据科学领域建立独立，成功的职业。 omics- 从基因组学到微生物组不等，已经彻底改变了生物医学科学。随着它们已经成为 在任何生物医学领域的一部分，每个学科中劳动力的稀缺性都有适当的OMIC培训具有 成为一个关键挑战。我们试图制定一个11个月的计划，以提供深入的培训 来自全国70多个指导者的潜水网络的OMICS和数据科学以及专门指导。职业 模式还将采用专业技能的培训，包括领导和团队管理，格兰特 写作，心理，目标设定和战略制定，沟通和教学，科学严谨， 透明度，可重复性，负责任的研究和健康公平。通过利用其全国 一组导师和培训，职业模式还将提供一种结构化的方法来增强合作 和网络，帮助创建突破性研究项目的团队以及K99/R00和R01型赠款 建议，进一步的职业发展，并帮助确保终身任职职位和教师晋升。 职业模式将以混合（虚拟和面对面的）课程和学习活动为特色（新兵训练营， 圆桌会议，面板，研讨会，观察验证），对每个目标的强大评估，并将产生和 传播有关OMICS和数据科学的广泛教育材料。该计划将与 最有前途的，有动力和潜水的初级调查员（传统上有限的资源 - 创建有能力的科学家人来通过高级知识和工具来追求独立性 适用于所有生物医学研究领域的OMICS和数据科学。那，我们的计划与纽约一致 目标并为投资带来很高的回报。我们还将制定促进股权和访问的策略 在OMICS研究并促进职业模式向学术机构，赞助商和利益相关者联系 财务可持续性和自支撑件超过R25资金五年。