Interpersonal Emotion Regulation in Neurodegenerative Disease: Pathways to Caregiver Health

神经退行性疾病中的人际情绪调节：护理人员健康之路

• 批准号: 10283585
• 负责人: Casey Leigh Brown
• 金额: $ 12.01万
• 依托单位: UNIVERSITY OF CALIFORNIA BERKELEY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-08-15 至 2022-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10283585
• 关键词: Acute; Address; Adult; Affect; Aging; Alzheimer' s Disease; Area; Atrophic; Behavior; Behavioral; Biological Markers; Blood; Brain region; California; Caregiver well-being; Caregivers; Caring; Characteristics; Cognitive; Collection; Conflict (Psychology); Critical Pathways; Cues; Data Collection; Development; Disease; Disease Pathway; Elderly; Emotional; Emotions; Empathy; Environment; Equation; Face; Goals; Growth; Health; Health Psychology; Impairment; Individual; Laboratories; Lead; Light; Link; Measurement; Medial; Memory; Mental Health; Mentorship; Modeling; Neurodegenerative Disorders; Outcome; Pathway interactions; Prevalence; Process; Psychology; Reporting; Research; Research Training; San Francisco; Sinus Arrhythmia; Social Network; Social support; Spouse Caregiver; Statistical Models; Stress; Structure; Techniques; Technology; Time; Training; Universities; Visual attention; adverse outcome; archive data; archived data; base; behavioral variant frontotemporal dementia; care recipients; career; caregiving; disorder control; effective intervention; emotion regulation; emotional stimulus; experience; flexibility; functional disability; indexing; loved ones; negative affect; neuroimaging; physical conditioning; positive emotional state; relating to nervous system; respiratory; response; showing emotion; skills; stressor; visual tracking

PROJECT SUMMARY Neurodegenerative diseases lead to profound cognitive, emotional, and functional impairments that leave individuals dependent upon close relational partners who provide care. Although caregiving is a positive experience for many individuals, providing care for an individual who has socioemotional deficits due to neurodegenerative disease can lead to adverse consequences for spousal caregivers, including poor mental and physical health outcomes. However, little research examines the dyadic, interpersonal pathways through which care recipients’ socioemotional deficits lead to health problems for their caregivers. The current research focuses on interpersonal emotion regulation – the extent to which a caregiver’s negative emotion is downregulated and a caregiver’s positive emotion is upregulated during conflict and an acute stressor with their care recipient – as a potential pathway linking care recipients’ socioemotional deficits to their caregivers’ health problems. The research will compare neurotypicals with individuals who have Alzheimer’s Disease (AD) and behavioral variant frontotemporal dementia (bvFTD) to understand how these different disease types influence interpersonal emotion regulation (Aim 1). The research will delineate the neural, autonomic, and behavioral correlates of interpersonal emotion regulation (Aim 2), with an emphasis on disease related atrophy, autonomic, and behavioral factors theorized to subserve interpersonal emotion regulation, including vagal flexibility, visual attention to other’s emotional expressions, and empathy. Finally, this research will examine whether poor interpersonal emotion regulation impacts caregiver health longitudinally (Aim 3). To support the candidate in conducting the proposed research, training is planned in: (a) measurement of changes in respiratory sinus arrhythmia as an index of vagal flexibility, (b) stationary and mobile eye-tracking technologies to capture visual attention to emotional stimuli, (c) health psychology and the collection of blood based health biomarkers, and (d) statistical growth modelling techniques in a structural equation modeling framework. The research environments within the Department of Psychology at the University of California, Berkeley, and the Memory and Aging Center at the University of California, San Francisco, will be ideal for the proposed training and research goals, as well as for developing the candidate’s professional skills. Training will occur under the mentorship of renowned experts in each area of training, and will support the candidates career goal of transitioning into an independent research career. The proposed research will provide a more nuanced framework for understanding how socioemotional impairments due to neurodegenerative diseases affect caregivers’ health over time, and advance our understanding of interpersonal emotion regulation and the dyadic processes that promote or hinder health in late life.

项目总结

项目成果

Empathic Accuracy and Shared Depressive Symptoms in Close Relationships.

亲密关系中的共情准确性和共同的抑郁症状。

• DOI: 10.1177/21677026221141852
• 发表时间: 2023
• 期刊: Clinical psychological science : a journal of the Association for Psychological Science
• 作者: Brown,CaseyL;Grimm,KevinJ;Wells,JennaL;Hua,AliceY;Levenson,RobertW
• 通讯作者: Levenson,RobertW