Exercising Together: A Randomized Controlled Trial of Partnered Exercise Training on the Health of Couples Coping with Cancer-Promote Diversity

增刊摘要 非裔美国人(AA)常见癌症的幸存者-前列腺癌(PC)、结直肠癌(CRC)或乳腺癌(BC)- 与非西班牙裔白人幸存者相比，结果更差，如果已婚，配偶/伴侣和关系 健康受到不利影响。研究改善再生障碍性贫血及其预后的策略的影响 亲密伴侣很少。纳入文化相关战略的定向招聘可能会有所帮助 AA参与者对筛选和参与以夫妇为基础的研究的兴趣/意愿。这个 父母对这项补充的资助是一项功效试验(一起锻炼试验；R01CA218093)，以确定 团队合作的好处，通过合作锻炼计划，在身体上、情感上和人际关系上 癌症幸存者及其亲密伴侣的健康状况。参加家长研究的AA夫妇的注册人数为 低于预期的比率，为补充项目提供了雇用社区参与的机会 以及与文化相关的战略，以提高父母研究中AA夫妇应对癌症的登记人数 也推动了为未来的试验收集初步数据，特别是在AA夫妇应对癌症的试验中。 该研究项目将在美国的两个不同地区使用社区参与工作室的方法。 (太平洋西北和东南)，以确定AA夫妇参与夫妻活动的促进者和障碍- 基于锻炼研究，特别是在一起锻炼协议中。社区参与工作室 将在俄勒冈州波特兰和田纳西州诺克斯维尔进行(通知家长研究的改编) 未来研究的背景)。调查人员将使用来自社区参与工作室的信息来 制定、实施和评估与文化相关的招聘策略和练习的交付 共同计划，将促进AA夫妇与癌症的接触。这份副刊也 支持对年轻、代表性不足的研究人员进行培训，以努力增加癌症的多样性--以及 与健康相关的研究人员。培训机会将加强学员的使用技能 社区参与的方法，以适应AA癌症夫妇的计划。本副刊将提供 实习生获得了与癌症幸存者及其亲密伴侣合作的新机会，这一群体 可以从父母研究的二元方法中获得身体和情感上的好处。这将移动 实习生朝着减少健康差距的目标前进，并推进了她的培训，以介绍一个重要的 美国临床人群的发病率和死亡率。这一经历将在 提交一份独立的资助建议，结合指导和技能 补充提供，将有助于引导她实现她的目标，实现独立资助的研究 程序。总而言之，这种独特的、与文化相关的以夫妻为基础的方法可以增加这种潜力 家长研究的影响，以及本补编的工作总体上可能最终有助于减少 癌症差异。

Supplement Abstract African American (AA) survivors of common cancers - prostate (PC), colorectal (CRC), or breast cancer (BC) - have poorer outcomes than non-Hispanic White survivors and if married, spouse/partner and relationship health is adversely impacted. Research studying the impact of strategies to improve outcomes in AAs and their intimate partners is scarce. Targeted recruitment which incorporates culturally relevant strategies may help with AA participants’ interest in/willingness to be screened for and participate in couples-based research. The parent grant to this supplement is an efficacy trial (the Exercising Together trial; R01CA218093) to determine the benefits of teamwork, through a partnered exercise program, on physical, emotional, and relationship health among cancer survivors and their intimate partners. Enrollment of AA couples in the parent study has fallen short of anticipated rates, providing an opportunity for supplement project to employ community-engaged and culturally relevant strategies to enhance enrollment of AA couples coping with cancer in the parent study and also an impetus to collect preliminary data for a future trial specifically in AA couples coping with cancer. The research project will use a Community Engagement Studio approach in two different regions of the U.S. (Pacific Northwest and Southeast) to identify facilitators and barriers to AA couples’ participation in couples- based exercise research and specifically in the Exercising Together protocol. Community Engagement Studios will be conducted in Portland, OR (to inform adaptations to the parent study) and Knoxville, TN (to provide context for future research). Investigators will use information from the Community Engagement Studio to develop, implement, and evaluate culturally relevant recruitment strategies and delivery of the Exercising Together program that will promote engagement of AA couples coping with cancer. This supplement also supports training for a young, underrepresented investigator in an effort to increase diversity in the cancer- and health-related research workforce. The training opportunity will strengthen the trainee’s skillset in using community-engaged approaches to adapt a program for AA couples with cancer. This supplement will provide the trainee with a new opportunity to work with cancer survivors and their intimate partners, a demographic that can benefit both physically and emotionally from the dyadic approach of the parent study. This moves the trainee toward her goal of reducing health disparities and advances her training to introduce an important clinical population in terms of incidence and mortality in the U.S. The experience will culminate in the submission of an independent grant proposal that in combination with the mentorship and skills this supplement provides, will help steer her toward her goal of achieving an independently funded research program. In summary, this unique and culturally relevant couples-based approach could increase the potential impact of the parent study, and the work of this supplement overall could ultimately contribute to reduced cancer disparities.