Whole Body Vibration Training for Healthy Body Composition in Young Adults
全身振动训练促进年轻人健康的身体成分
基本信息
- 批准号:8884853
- 负责人:
- 金额:$ 18.18万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2013
- 资助国家:美国
- 起止时间:2013-08-08 至 2017-06-30
- 项目状态:已结题
- 来源:
- 关键词:AddressAdipose tissueAdjuvantAdolescentAdultAgeAge-YearsAmericanAttentionBehavioralBody CompositionBody WeightBody fatChildChronicChronic DiseaseClinicalClinical ResearchClinical TrialsControl GroupsCounselingCoupledDataDevelopmentDiabetes MellitusDietary InterventionDiseaseDual-Energy X-Ray AbsorptiometryElderlyEnvironmentEpidemicEvidence based interventionExerciseExposure toFatty acid glycerol estersFitness CentersFrequenciesFutureGoalsHabitsHealthHeart DiseasesHome environmentIndividualInterventionKnowledgeLifeLife StyleMaintenanceMalignant NeoplasmsMeasuresMechanicsMedicalMetabolic syndromeMethodsMotivationMusculoskeletal SystemObesityObesity associated diseaseOutcomeOutcome MeasureOverweightParticipantPopulationPreventionPrevention programPublic HealthPublishingRandomized Controlled TrialsRattusRecruitment ActivityRehabilitation therapyRelaxationReportingResearchResearch Project GrantsResidenciesRiskRisk FactorsSafetySignal TransductionStrokeTechniquesTestingTherapeuticTimeTrainingTraining ProgramsUnited States National Institutes of HealthVisceralWeightWeight GainWorkabdominal fatage groupage relatedbasecopingcost effectivecritical perioddesigndiet and exerciseeffective interventionevidence baseexpectationexperiencefightinghigh riskimprovedinnovationintervention programmuscle formnovelnovel strategiesnovel therapeuticspreventprimary outcomeprogramssocialsuccessful interventionvibrationweight gain preventionyoung adult
项目摘要
DESCRIPTION (provided by applicant): Young adults (18-24 years) are particularly prone to unhealthy changes in body composition (average weight gain 30 pounds) that predispose them to development of obesity-related diseases. The proposed research is designed to test the novel hypothesis that active participation in whole-body vibration (WBV) training will result in suppression of accumulation of fat, maintenance of lean muscle mass and reduced levels of risk factors as- sociated with obesity. WBV involves a unique method of stimulating the musculoskeletal system through pas- sive application of high frequency, low amplitude mechanical signals. Based upon our preliminary data and published findings, it is hypothesized that, at the end of 6-months, young adults receiving a 20-minute of WBV 3 d/wk, will not experience weight gain but will instead maintain lean muscle mass compared to those assigned to the control group. This hypothesis is based on our strong preliminary studies, in which we have shown that repeated exposure to WBV reduced age-related increases in fat mass in mature rats while maintaining lean muscle mass. Additional preliminary findings in older adults suggest a WBV intervention to be effective in re- ducing body mass, fat mass and percent body fat while maintaining lean mass. In the proposed study, a 6- month randomized controlled trial will be carried out with two groups: 1) WBV and 2) attention control relaxa- tion group, to test th hypothesis by through the following Aim: To evaluate the therapeutic benefits and feasi- bility of implementing a whole-body vibration (WBV) exercise training program as a method of preventing weight gain and increases in fat mass in physically inactive young adults (18-24 yrs.). Primary outcome meas- ures include: Total body weight, % body fat, fat mass, visceral adipose tissue, and fat free mass, measured by dual energy X-ray absorptiometry (DXA). The proposed study is potentially innovative because it capitalizes on a new therapeutic technique - WBV to improve body composition by stimulating the musculoskeletal system through the passive application of high frequency, low amplitude mechanical signals. Successful completion of the proposed research would establish WBV training as a safe and feasible program with high compliance and acceptability for preventing weight gain in young adults. At the end of 6-months, young adults receiving a 20- min. of WBV 3d/wk will have maintained their body weight and will have a healthier body composition (lean-fat mass). This application addresses the NIH strategic goal to encourage exploratory/developmental clinical re- search that will accelerate development of effective interventions for prevention or treatment of overweight and/or obesity in adults and/or children and, PA-09-124 Exploratory/Developmental Clinical Research Grants in Obesity (R21). This new and substantively different approach is expected to overcome difficulties of recruiting, retaining, and motivating young adults to remain weight stable, often associated with other long term weight programs, thereby resulting in an efficacious approach to weight gain prevention. !
描述(由申请人提供):年轻人(18-24岁)特别容易发生身体成分的不健康变化(平均体重增加30磅),使他们容易患上肥胖相关疾病。这项研究旨在验证一个新的假设,即积极参与全身振动(WBV)训练将抑制脂肪积累,维持瘦肌肉质量,并降低与肥胖相关的风险因素水平。WBV涉及通过无源应用高频、低振幅机械信号刺激肌肉骨骼系统的独特方法。根据我们的初步数据和已发表的研究结果,假设在6个月结束时,接受20分钟WBV 3 d/wk的年轻成年人与对照组相比,不会出现体重增加,而是保持瘦肌肉质量。这一假设是基于我们强有力的初步研究,其中我们已经表明,反复暴露于WBV减少了成熟大鼠中与年龄相关的脂肪量增加,同时保持了瘦肌肉量。在老年人中的其他初步研究结果表明,WBV干预可有效降低体重、脂肪量和体脂百分比,同时保持瘦体重。在拟定的研究中,将进行一项为期6个月的随机对照试验,分为两组:1)WBV组和2)注意力控制放松组,通过以下目的检验假设:评价实施全身振动(WBV)的治疗获益和可行性运动训练计划作为预防体重增加和脂肪量增加的方法,在身体不活跃的年轻人(18-24岁)。主要结局指标包括:总体重、%体脂、脂肪量、内脏脂肪组织和去脂肪量,通过双能X线吸收测定法(DXA)测量。拟议的研究具有潜在的创新性,因为它利用了一种新的治疗技术- WBV,通过被动应用高频,低振幅机械信号刺激肌肉骨骼系统来改善身体成分。成功完成拟议的研究将建立WBV培训作为一个安全和可行的计划,具有高度的依从性和可接受性,以防止体重增加的年轻人。在6个月结束时,接受20分钟WBV 3天/周的年轻成年人将保持他们的体重,并将具有更健康的身体组成(瘦脂肪质量)。本申请涉及NIH的战略目标,即鼓励探索性/开发性临床研究,以加速开发预防或治疗成人和/或儿童超重和/或肥胖症的有效干预措施,以及PA-09-124肥胖症探索性/开发性临床研究赠款(R21)。这种新的和实质性不同的方法预计将克服招募,保留和激励年轻人保持体重稳定的困难,通常与其他长期体重计划相关,从而产生有效的预防体重增加的方法。!
项目成果
期刊论文数量(1)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
A brief whole-body vibration intervention to avoid weight gain in college students: A randomized controlled pilot trial.
避免大学生体重增加的简短全身振动干预:一项随机对照试点试验。
- DOI:10.1080/07448481.2020.1784179
- 发表时间:2022
- 期刊:
- 影响因子:0
- 作者:Winters-Stone,KerriM;Medysky,MaryE;Stoyles,Sydnee;Bumgarner,Lauren;Witzke,Kara
- 通讯作者:Witzke,Kara
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KERRI M WINTERS-STONE其他文献
KERRI M WINTERS-STONE的其他文献
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{{ truncateString('KERRI M WINTERS-STONE', 18)}}的其他基金
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