Longitudinal Examination of Sluggish Cognitive Tempo and Internalizing Psychopathology in Adolescence

青春期迟缓认知节奏和内化精神病理学的纵向检查

• 批准号: 10308099
• 负责人: Stephen P Becker
• 金额: $ 75.5万
• 依托单位: CINCINNATI CHILDRENS HOSP MED CTR
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-12-01 至 2025-10-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10308099
• 关键词: Accounting; Address; Adolescence; Adolescent; Advanced Development; Age; Anxiety; Attention deficit hyperactivity disorder; Behavioral; Behavioral Symptoms; Behavioral inhibition; Child; Clinical; Clinical Treatment; Clinical assessments; Cognitive; Communities; Complex; Confusion; Cross-Sectional Studies; Data; Daydreams; Development; Dimensions; Failure; Feeling suicidal; Fibrinogen; Goals; Link; Loneliness; Measures; Mediating; Mental Depression; Methods; Modeling; National Institute of Mental Health; Outcome; Parents; Participant; Patient Self-Report; Physiological; Positioning Attribute; Psychopathology; Punishment; Research; Research Domain Criteria; Sampling; School-Age Population; Self Efficacy; Social Environment; Suicide; Sum; Sympathetic Nervous System; Symptoms; System; Temperament; Testing; Theoretical model; Thinking; Time; Withdrawal; Youth; associated symptom; base; cognitive change; cognitive process; design; early adolescence; functional disability; informant; peer; prospective; recruit; rumination; social; suicidal risk; symptomatology; teacher

PROJECT SUMMARY/ABSTRACT Sluggish cognitive tempo (SCT) is a set of behavioral symptoms characterized by excessive daydreaming, slowed thinking, and mental confusion and fogginess. It is now established that SCT can be reliably measured across parent, teacher, and self-report ratings and is distinct from other psychopathology dimensions including ADHD and internalizing symptoms. A rapidly growing body of research also demonstrates SCT to be strongly associated with functional impairment, above and beyond other psychopathologies. However, SCT remains absent from current models of psychopathology, in large part because the field lacks rigorous longitudinal research examining SCT in relation to other psychopathologies. In cross-sectional studies, SCT symptoms are consistently and strongly associated with internalizing symptoms. Preliminary findings also document associations between SCT and increased suicide risk. Importantly, our pilot data show SCT predicts increased internalizing symptoms rather than the reverse. Further, SCT symptoms uniquely predict internalizing problems and not externalizing behaviors, suggesting that SCT may be a unique factor in understanding the development of internalizing problems specifically. Yet studies linking SCT to internalizing symptoms in youth are limited in several ways, including: (a) use of cross-sectional designs that preclude establishment of temporal associations, (b) using convenience samples (e.g., ADHD) rather than a sample enriched for SCT specifically, (c) failing to examine possible mechanisms or vulnerabilities linking SCT to internalizing symptoms, and (d) focusing on school-aged children even though SCT symptoms and internalizing problems sharply increase in adolescence. This study will address these limitations by using a prospective longitudinal, multi-informant, multi-method design across the developmentally sensitive period of early adolescence to examine SCT symptoms as a predictor of diverse internalizing outcomes and to test mechanisms and vulnerabilities linking SCT to internalizing symptoms in a community sample enriched for SCT symptomatology. Specifically, a community-based sample of 330 young adolescents (ages 10-12 years) enriched for SCT symptomatology will be recruited and assessed at three timepoints one year apart. Consistent with the NIMH Research Domain Criteria (RDoC) initiative and a developmental psychopathology framework, a multi-informant, multi-method battery that cuts across physiological, behavioral, and self-report units of analysis will be used. We will examine dimensional SCT symptoms as a predictor of internalizing psychopathology change over time, test mechanisms of the longitudinal relation between SCT and internalizing psychopathologies, and explore vulnerabilities (physiological reactivity, punishment sensitivity) that exacerbate these longitudinal relations. Findings establishing longitudinal effects and identifying mechanisms and vulnerabilities that cut across units of analysis will advance the development of theoretical models of SCT. Findings from this study will also provide avenues for targeted clinical assessment and treatment.

项目摘要/摘要 迟钝的认知节奏（SCT）是一组行为症状，其特征是白日梦， 思维放缓，精神混乱和雾蒙蒙。现在确定可以可靠地测量SCT 跨父母，老师和自我报告评级，与其他心理病理学维度不同，包括 多动症和内在症状。快速增长的研究也表明SCT是强烈的 与功能障碍相关，超越其他心理病理学。但是，SCT仍然存在 目前的心理病理学模型不存在，在很大程度上是因为该领域缺乏严格的纵向 研究研究了与其他心理病理学有关的SCT。在横断面研究中，SCT症状是 一致，与内在症状密切相关。初步发现也有记录 SCT与自杀风险增加之间的关联。重要的是，我们的飞行员数据显示SCT预测增加 内部症状而不是反向。此外，SCT症状独特地预测内在问题 而不是外部化行为，表明SCT可能是理解的独特因素 专门开发内部化问题。然而，将SCT与青年内部症状联系起来的研究 受到多种方式受到限制，包括：（a）使用横截面设计，无法建立 时间关联，（b）使用便利样本（例如ADHD），而不是富含SCT的样品 具体而言，（c）未能检查将SCT连接到内部化的可能机制或漏洞 症状，（d）关注学龄儿童，即使SCT症状和内在问题 青春期急剧增加。这项研究将通过使用前瞻性纵向解决这些局限 跨青春期的发育敏感时期的多信息，多方法设计 检查SCT症状是各种内在化结果和测试机制的预测指标 将SCT与富含SCT的社区样本中的内在症状联系起来的漏洞 症状学。具体而言，一个基于社区的330名青少年（10-12岁）的样本 富含SCT症状的富含症状将在一年相隔一年的三个时间点招募和评估。 与NIMH研究领域标准（RDOC）倡议和发展心理病理学一致 框架，一种多信息，多方法电池，跨生理，行为和自我报告 将使用分析单位。我们将检查尺寸SCT症状作为内在化的预测指标 心理病理学随着时间的变化，SCT和内在化之间纵向关系的测试机制 精神病理学，探索加剧的脆弱性（生理反应性，惩罚敏感性） 这些纵向关系。建立纵向效应和识别机制的发现和 切断分析单位的脆弱性将推动SCT理论模型的发展。 这项研究的结果还将为有针对性的临床评估和治疗提供途径。