The Role of Stem Cells and the Microenvironment in Gastrointestinal Cancers
The Role of Stem Cells and the Microenvironment in Gastrointestinal Cancers
批准号:
10307622
负责人:
Timothy Cragin Wang
金额:
$89.38万
依托单位国家:
美国
项目类别:
财政年份:
2016
资助国家:
美国
项目状态:
已结题
起止时间:
2016-12-07 至 2023-11-30
关键词:
3-DimensionalAreaCancer ControlCell modelChronicCollaborationsCollectionColonColon CarcinomaCre driverDevelopmentElementsEndothelial CellsEpithelialEsophagusEvolutionFibroblastsGenetically Engineered MouseHelicobacterHelicobacter InfectionsImmunityIn VitroInflammationInvestigationLaboratoriesLymphoid CellMalignant NeoplasmsMalignant neoplasm of esophagusMalignant neoplasm of gastrointestinal tractMalignant neoplasm of pancreasModelingMutateMyeloid CellsMyeloproliferative diseaseNatural regenerationNerveOrganoidsPancreasPathogenesisPre-Clinical ModelRegulationRoleStomachStomach NeoplasmsStromal CellsTestingTumor ImmunityWorkcancer cellcell behaviorcholinergicimprovedmalignant stomach neoplasmneuroregulationprogenitorprogramsstem cell nichestem cellstumortumor microenvironmenttumor progression
中文摘要
点击翻译按钮获取中文摘要
英文摘要
Summary/Abstract
This project seeks to investigate the role of nerves and other stromal cells in the development of
digestive cancers, including stomach, esophageal, colon and pancreas. The project builds on
previous work that suggests that these elements can regulate stem cells, and that inhibiting
stromal cells in the microenvironment, it may be possible to inhibit the development of tumors.
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会议论文
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Gastrin Regulation of Gastric Antral Stem and Corpus Progenitor Cells
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资助金额:$49.9万
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财政年份:2021
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负责人:Timothy Cragin Wang
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Gastrin Regulation of Gastric Antral Stem and Corpus Progenitor Cells
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批准号:10367556
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资助金额:$49.9万
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财政年份:2021
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负责人:Timothy Cragin Wang
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The Role of Stem Cells and the Microenvironment in Gastrointestinal Cancers
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批准号:10532704
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项目类别:
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资助金额:$89.38万
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财政年份:2016
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负责人:Timothy Cragin Wang
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依托单位:
The role of stem cells and the microenvironment in gastrointestinal cancers
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批准号:10737925
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资助金额:$98.7万
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财政年份:2016
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The Role of Stem Cells and the Microenvironment in Gastrointestinal Cancers
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批准号:9186833
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资助金额:$94.2万
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Quiescent Dclk1+ stem cells in the mouse intestine
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资助金额:$31.17万
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依托单位:
Quiescent Dclk1+ stem cells in the mouse intestine
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批准号:8577370
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项目类别:
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资助金额:$32.0万
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财政年份:2013
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依托单位:
Quiescent Dclk1+ stem cells in the mouse intestine
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批准号:8547458
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项目类别:
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资助金额:$34.78万
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财政年份:2012
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负责人:Timothy Cragin Wang
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依托单位:
Administrative and Bioinformatics Core
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批准号:8555379
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依托单位:
Myofibroblasts in Gastrointestinal Cancers
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批准号:8212777
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项目类别:
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资助金额:$50.5万
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财政年份:2011
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负责人:Timothy Cragin Wang
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依托单位:
Myofibroblasts in Gastrointestinal Cancers
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批准号:8705460
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项目类别:
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资助金额:$50.68万
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财政年份:2011
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Administrative and Bioinformatics Core
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批准号:8256912
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项目类别:
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资助金额:$11.36万
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财政年份:2011
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负责人:Timothy Cragin Wang
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依托单位:
Administrative Core
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批准号:10270338
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项目类别:
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资助金额:$16.2万
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财政年份:2011
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负责人:Timothy Cragin Wang
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依托单位:
Myofibroblasts in Gastrointestinal Cancers
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批准号:8701442
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项目类别:
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资助金额:$13.55万
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依托单位:
Myofibroblasts in Gastrointestinal Cancers
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批准号:8337299
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财政年份:2011
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Myofibroblasts in Gastrointestinal Cancers
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