Advancing the science on recovery community centers to support persons treated with medications for opioid use disorder: Administrative Supplement

推进康复社区中心的科学，以支持接受阿片类药物使用障碍药物治疗的人：行政补充

• 批准号: 10317332
• 负责人: Bettina B. Hoeppner
• 金额: $ 16.8万
• 依托单位: MASSACHUSETTS GENERAL HOSPITAL
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-15 至 2023-04-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10317332
• 关键词: Address; Administrative Supplement; Affective; Age; Autonomic nervous system; Behavioral Mechanisms; Biological; Boston; Capital; Cities; Clinical; Cognitive; Communities; Coping Skills; Criminal Justice; Disease; Disease remission; Elements; Environment; Evaluation; Exercise; Fees; Focus Groups; Foundations; Funding; Future; Goals; Grant; Individual; Institution; Intervention; Knowledge; Leadership; Measures; Mediator of activation protein; Monoclonal Antibody R24; Narcotics; National Institute of Drug Abuse; Nervous System Physiology; Opioid; Parents; Participant; Patients; Persons; Pharmaceutical Preparations; Physical Exercise; Physical Fitness; Physical activity; Predisposition; Program Evaluation; Psychophysiology; Public Health; Qualitative Evaluations; Quantitative Evaluations; Recovery; Recreation; Research; Research Activity; Research Infrastructure; Resources; Rest; Running; Science; Self Efficacy; Services; Severities; Social Change; Social Network; Stress; Substance Use Disorder; System; Testing; Therapeutic; United States; Yoga; addiction; base; behavior change; biobehavior; community center; comparative; cost; design; disorder later incidence prevention; experience; falls; innovation; instructor; interest; meetings; member; novel; opioid use; opioid use disorder; peer; pleasure; prescription opioid; program dissemination; programs; prospective; psychosocial; rapid growth; resilience; sex; social; stress reactivity; substance use; tool; volunteer

PROJECT SUMMARY/ABSTRACT The recently funded NIDA R24 entitled, Advancing The Science on Recovery Community Centers (RCCs) to Support Persons Treated With Medications for Opioid Use Disorder (R24 DA05198801) is an innovative project with the goal of cultivating and developing RCC research. Not included in this project, however, is a novel class of RCCs that support opioid and other substance use disorder recovery through peer-led physical activity and exercise. The goal of this supplement to R24 DA05198801 is to engage with and study a prototypical physical activity/exercise-based RCC known as The Phoenix, which provides a safe, recovery-oriented environment and a physically active community designed to attract and support individuals seeking addiction recovery. The Phoenix offers activities like CrossFit, rock-climbing, and yoga through a network of recovery-focused gyms. It has no fees, and its activities are run by peer volunteers who are themselves in addiction recovery. Its novel focus on physical activity, recreation, and integrating the biological with the psychosocial through leveraging the known positive benefits of engaging with others who have lived experience of addiction and recovery, has produced excitement in the field and garnered widespread interest from federal/state-level institutions, treatment systems, and criminal justice. Since its establishment in 2006, The Phoenix has grown rapidly to operate programming in 26 states with ~40,000 active members, and ~8,000 new members joining each year. The Phoenix has added programming in 25 new cities in 2020. Given the growing interest surrounding The Phoenix and its rapid expansion, there is a pressing need to understand its clinical and public health potential and explore moderators and mechanisms of its effects in a more systematic way. This need will be addressed in this study through the following aims that fit within the scope of the parent R24: 1) Engage Phoenix leaders in research- advancing activities promoting program evaluation and dissemination, and conduct focus groups with Phoenix members, peer instructors, and leadership to obtain greater contextual knowledge of participants’ experience with The Phoenix. 2) Conduct a comparative prospective, proof of concept, study (N=150; assessments at baseline, 1-, 3-, and 6-months) to test for improvements in substance use, psychosocial and psychophysiological functioning, relative to matched community controls, with psychophysiological assessments under resting and stress-reactivity conditions to explore changes in autonomic nervous system functioning. 3) Explore moderators of Phoenix’s effects that predict engagement, retention, and any derived benefits, as well as mediators through which Phoenix may confer benefit. Ultimately, this project will inform clinical decisions about patient referral to The Phoenix, and should Phoenix show signs of conferring benefit, create a foundation for future R01 clinical linkage trials.

项目摘要/摘要 最近资助的NIDA R24题为，推进恢复社区中心（RCCs）的科学， 支持阿片类药物使用障碍治疗者（R24 DA 05198801）是一个创新项目 以培育和发展RCC研究为目标。然而，这个项目中不包括一个新的类， 通过同伴主导的身体活动支持阿片类药物和其他物质使用障碍康复的RCC， 锻炼的本R24 DA 05198801补充的目标是参与和研究一个原型物理 基于活动/练习的RCC，称为Phoenix，它提供了一个安全的、面向恢复的环境， 一个体育活动社区，旨在吸引和支持寻求成瘾康复的个人。的 凤凰城通过一个以恢复为重点的健身房网络提供交叉健身、攀岩和瑜伽等活动。它 它不收取任何费用，它的活动由自己也在戒毒的同龄志愿者管理。其新颖 专注于身体活动，娱乐，并通过利用 与有过成瘾和康复经历的人接触的已知积极益处， 引起了该领域的兴奋，并引起了联邦/州一级机构的广泛兴趣， 制度和刑事司法。自2006年成立以来，凤凰网迅速发展， 在26个州开展方案活动，拥有约40 000名活跃成员，每年约有8 000名新成员加入。的 2020年，凤凰卫视在25个新城市增加了节目。鉴于人们对凤凰的兴趣越来越大 及其快速扩张，迫切需要了解其临床和公共卫生潜力，并探索 以更系统的方式研究其影响的调节剂和机制。本研究将解决这一需求 通过以下目标，符合范围内的母R24：1）从事凤凰领导人的研究- 推进促进计划评估和传播的活动，并与凤凰组织进行焦点小组讨论 成员、同伴教员和领导，以获得更多的参与者经验的背景知识 与凤凰号一起。2)进行一项比较性前瞻性、概念验证研究（N=150; 基线、1个月、3个月和6个月），以测试物质使用、心理社会和心理生理方面的改善 功能，相对于匹配的社区对照，在休息和 应激反应条件，以探索自主神经系统功能的变化。3)浏览版主 凤凰的影响，预测参与，保留，和任何衍生的好处，以及调解人，通过 菲尼克斯可能会带来好处。最终，该项目将为患者转诊的临床决策提供信息， Phoenix（如果Phoenix显示出获益迹象）为未来R 01临床奠定了基础 联动试验