Assessing Function and Performance of Population Sexual Orientation and Gender Identity (SOGI) Research Measures in a Racially Diverse HIV-Specific National Cohort

评估不同种族的艾滋病毒特定国家队列中人口性取向和性别认同 (SOGI) 研究措施的功能和表现

• 批准号: 10334307
• 负责人: Bradley E Aouizerat
• 金额: $ 9.98万
• 依托单位: UNIVERSITY OF CALIFORNIA, SAN FRANCISCO
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-04-01 至 2026-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10334307
• 关键词: AIDS prevention; Address; Area; Bisexual; Cohort Studies; Communication; Data; Data Collection; Ethnic Origin; Feeling suicidal; Funding; Gender; Gender Identity; Geographic Locations; Geography; Goals; HIV; HIV Seronegativity; HIV Seropositivity; Health; Healthcare; Homophobia; Individual; Institute of Medicine (U.S.); Latinx; Lead; Lesbian; Love; Malignant Neoplasms; Measurement; Measures; Medical; Mental Health; Methodology; Minority Groups; National Heart, Lung, and Blood Institute; Not Hispanic or Latino; Obesity; Outcome; Participant; Patients; Performance; Personal Satisfaction; Policies; Population; Population Heterogeneity; Population Research; Prevention; Prevention Research; Process; Prospective cohort; Race; Research; Research Personnel; Research Priority; Risk; Sampling; Sex Differentiation; Sex Orientation; Sexual Health; Sexual and Gender Minorities; Sexually Transmitted Diseases; Smoking; Standardization; Suicide attempt; Surveys; Testing; United States National Academy of Sciences; United States National Institutes of Health; Woman; cohort; data infrastructure; ethnic difference; ethnic diversity; experience; fluidity; follow-up; genderqueer; health difference; health disparity; improved; men who have sex with men; minority communities; pansexual; parent grant; prevent; racial and ethnic; racial diversity; racism; recruit; response; screening; social stigma; transgender men; transgender women; transmission process; transphobia; treatment research; two spirit

PROJECT SUMMARY / ABSTRACT Sexual and gender minority (SGM) people have higher rates of HIV and other sexually transmitted infections, suicidal ideation and attempts, obesity, cancer, poor mental health, and smoking and are at increased risk for poor health outcomes compared to non-SGM people. Yet how these disparities might be mitigated and prevented is unclear, in part because research among SGM populations suffers from challenges in capturing sexual orientation and gender identity (SOGI). These challenges include the ability to achieve accuracy when collected and to use questions that resonate and are understood by both SGM and non-SGM people. The existing evidence on accurately capturing SGM status lacks racial/ethnic diversity and skews toward mostly white SGM samples. Further, HIV prevention and treatment research efforts have evolved to target “key populations,” such as men who have sex with men (MSM) and transgender women who are at elevated risk for HIV transmission and acquisition. Transgender women and MSM, therefore, may be more familiar with survey questions that seek to assess SOGI than other SGM individuals and groups considered less at risk for HIV (e.g., lesbians, bisexual women, transgender men, non-binary people). Additionally, transphobia and homophobia are often experienced in and can contribute to a context of HIV stigma and may impact the ways in which SGM status is perceived and captured in HIV-specific settings. The intersections of racism and transphobia and/or homophobia can exacerbate HIV-related stigma, also contributing to measurement hurdles. Differences in the ways in which SGM individuals identify across US regions and cultures represent another barrier to capturing accurate SGM status in data collection. To determine the best way to differentiate SGM people from non-SGM people in population research, it is essential to assess such measures in racially/ethnically diverse populations and unique contexts. This supplement leverages the data and infrastructure of two NIH-funded studies (parent grant: U01HL146242; PI: Tien and R21MD015878; PI: Obedin-Maliver) with the primary goal of expanding measurement testing to the MACS-WIHS Combined Cohort Study, a prospective cohort of geographically and racially/ethnically diverse individuals living with or at risk of HIV in the US. This supplement's aims are to: (1) Assess the function and performance of an SGM status screening question and SOGI question sets in a racially/ethnically diverse US cohort of people living with or at risk for HIV via the MWCCS; and (2) Determine the function and performance among SGM and non- SGM people who are (a) HIV-negative and HIV-positive and (b) in HIV-specific and non-HIV-specific study settings in the MWCCS, The Population Research in Identities and Disparities for Equality (PRIDE) Study, and the Health eHeart (HeH) Study. The aims of this supplement are aligned with NHLBI's objective to “investigate factors that account for differences in health among populations” and NIH SGM high priority research areas.

项目摘要 /摘要 性和性别少数民族（SGM）的艾滋病毒和其他性传播感染率较高， 自杀的构想和尝试，肥胖，癌症，精神健康和吸烟不良，并有增加的风险 与非SGM人相比，健康状况不佳。然而，如何减轻这些分布和 预防尚不清楚，部分是因为SGM人口的研究面临着捕获的挑战 性取向和性别认同（SOGI）。这些挑战包括能够在 收集并使用引起共鸣的问题，并被SGM和非SGM人所理解。 现有关于准确捕获SGM身份的证据缺乏种族/种族多样性，并且主要偏向于 白色SGM样品。此外，艾滋病毒预防和治疗研究工作已经发展为目标“关键 人群，“例如与男性发生性关系的男人（MSM）和跨性别妇女的风险较高 HIV传播和获取。因此，变性妇女和MSM可能更熟悉调查 试图评估SOGI的问题比其他SGM个人和团体认为艾滋病毒的风险较小 （例如，女同性恋，双性恋妇女，变性男人，非二元人）。另外，恐惧症和 同性恋恐惧症经常经历并可能导致艾滋病毒污名的背景，并可能影响方式 其中在特定于HIV的设置中感知和捕获了SGM状态。种族主义和 恐惧症和/或同性恋恐惧症会加剧与HIV相关的污名，这也导致了测量障碍。 SGM个人在美国各地区和文化中识别的方式的差异代表了另一种 在数据收集中捕获准确的SGM状态的障碍。确定区分SGM的最佳方法 来自非SGM人群研究中的人，必须评估此类措施 种族/种族多样化的人群和独特的环境。此补充利用数据， 两项NIH资助研究的基础设施（父母赠款：U01HL146242; PI：Tien和R21MD015878; PI： Obedin-maliver）的主要目标是将测量测试扩展到Macs-Wihs合并 队列研究，地理和大致/种族多样化的人群的前瞻性队列 在美国艾滋病毒的风险。该补充的目的是：（1）评估SGM的功能和性能 状态筛查问题和Sogi问题集中在大致/种族多样化的我们的同类中 通过MWCCS或有艾滋病毒的风险； （2）确定SGM和非 - SGM的人（a）HIV阴性和HIV阳性以及（b）在HIV特异性和非HIV特异性研究中 MWCC中的设置，平等认同和差异的人口研究（Pride）研究以及 健康EHEART（HEH）研究。这种补充的目的与NHLBI的目标保持一致 解释人群中健康差异的因素和NIH SGM高优先研究领域。