SUPPORT SERVICES FOR THE HIV AIDS CLINICAL TRIALS NETWORKS

尤尼斯·肯尼迪·施莱弗国家儿童健康与人类发展研究所(NICHD)需要持续和经常性的后勤、技术和行政支持，以维持、协调和管理国内和国际临床中心的多站点网络，这些中心从事儿童、青少年和孕产妇健康患者群体中艾滋病毒感染和疾病及其传染性和非传染性并发症的治疗、预防、诊断、流行病学和自然历史研究。 该任务单将提供实施、维护、协调和管理多站点临床中心网络所需的所有必要服务、合格人员、材料、设备和设施，以进行临床试验，以评估儿科、青少年和孕产妇健康患者群体中HIV感染的多个方面的调查治疗、诊断技术、预防策略、流行病学和自然病史。 支持IMPAACT、ATN、ACTG、Insight Networks的临床工作。 确保站点能够访问实验室设施，能够执行病毒学、免疫学、药理学和其他实验室分析、标本处理以及IMPAACT/ACTG/Insight/ATN或NICHD临床中心参与的其他网络协议指定的标本存储。选定的病毒学和免疫学分析将需要NIAID认证的实验室(如 检测可以在NIAID认证的实验室进行，即NICHD网络站点或非NICHD网络站点)。 为实施和监测多项正在进行的和未来的临床试验提供服务，以支持IMPACCT、ACTG、Insight和ATN网络。

The Eunice Kennedy Shriver National Institute for Child Health and Human Development (NICHD) requires continuous and recurring logistical, technical, and administrative support to maintain, coordinate, and manage a multi-site network of domestic and international clinical centers conducting research on treatment, prevention, diagnosis, epidemiology, and natural history of HIV infection and disease and its infectious and non-infectious complications in pediatric, adolescent, and maternal health patient populations. This Task Order will provide all the necessary services, qualified personnel, materials, equipment, and facilities needed to implement, maintain, coordinate, and manage a multi-site network of clinical centers to conduct clinical trials for evaluation of investigational therapies, diagnostic techniques, prevention strategies, epidemiology and natural history of multiple aspects of HIV infection in pediatric, adolescent, and maternal health patient populations. Support the clinical works in IMPAACT, ATN, ACTG, INSIGHT Networks. Ensure sites have access to laboratory facilities with capability to perform virologic, immunologic, pharmacologic, and other laboratory assays, specimen processing, and specimen storage specified by IMPAACT/ACTG/INSIGHT/ATN or other Network protocols in which NICHD clinical centers participate. Selected virologic and immunologic assays will require performance by a NIAID certified laboratory (such testing may be done at NIAID-certified laboratories that are NICHD Network sites or non-NICHD Network sites). Provide services for implementation and monitoring of multiple ongoing and future clinical trials in support of the IMPACCT, ACTG, INSIGHT, ATN Networks.