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中文摘要
翻译
摘要 细菌病原体艰难梭状芽孢杆菌被认为是对美国医疗保健的紧急威胁 疾病控制中心的系统。艰难梭菌为了引发感染,其感染性孢子形态 必须在易感人群的肠道中萌发。由于孢子萌发依赖于孢子细胞壁 在经历了特定的修饰之后,确定艰难梭菌中这一过程是如何发生的,可能会让 制定预防艰难梭菌疾病传播和复发的策略。
英文摘要
SUMMARY The bacterial pathogen, Clostridioides difficile, has been designated an urgent threat to the US healthcare system by the Centers for Disease Control. In order for C. difficile to initiate infection, its infectious spore form must germinate in the gut of susceptible individuals. Since spore germination depends on the spore cell wall undergoing specific modifications, determining how this process occurs in C. difficile could inform the development of strategies for preventing C. difficile disease transmission and recurrence.
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Regulation of spore peptidoglycan modification
  • 批准号:
    10530682
  • 项目类别:
  • 资助金额:
    $32.37万
  • 财政年份:
    2021
  • 负责人:
    Aimee Shen
  • 依托单位:
Linking Gene Expression Profiles to Cell Fate in Clostridioides difficile Using Time-Lapse Microscopy
  • 批准号:
    10330034
  • 项目类别:
  • 资助金额:
    $24.36万
  • 财政年份:
    2021
  • 负责人:
    Aimee Shen
  • 依托单位:
Regulation of spore peptidoglycan modification
  • 批准号:
    10096439
  • 项目类别:
  • 资助金额:
    $35.62万
  • 财政年份:
    2021
  • 负责人:
    Aimee Shen
  • 依托单位:
Linking Gene Expression Profiles to Cell Fate in Clostridioides difficile Using Time-Lapse Microscopy
  • 批准号:
    10223787
  • 项目类别:
  • 资助金额:
    $21.86万
  • 财政年份:
    2021
  • 负责人:
    Aimee Shen
  • 依托单位:
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