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中文摘要
翻译
总结 细菌病原体艰难梭菌已被指定为对美国医疗保健的紧迫威胁 疾病控制中心的系统。为了使C.很难启动感染,其感染性孢子形式 必须在易感个体的肠道中发芽由于孢子萌发依赖于孢子细胞壁 经历特定的修改,确定这个过程如何在C中发生。difficile可以告知 制定预防C.艰难梭菌病的传播和复发
英文摘要
SUMMARY The bacterial pathogen, Clostridioides difficile, has been designated an urgent threat to the US healthcare system by the Centers for Disease Control. In order for C. difficile to initiate infection, its infectious spore form must germinate in the gut of susceptible individuals. Since spore germination depends on the spore cell wall undergoing specific modifications, determining how this process occurs in C. difficile could inform the development of strategies for preventing C. difficile disease transmission and recurrence.
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Regulation of spore peptidoglycan modification
  • 批准号:
    10530682
  • 项目类别:
  • 资助金额:
    $32.37万
  • 财政年份:
    2021
  • 负责人:
    Aimee Shen
  • 依托单位:
Linking Gene Expression Profiles to Cell Fate in Clostridioides difficile Using Time-Lapse Microscopy
  • 批准号:
    10330034
  • 项目类别:
  • 资助金额:
    $24.36万
  • 财政年份:
    2021
  • 负责人:
    Aimee Shen
  • 依托单位:
Regulation of spore peptidoglycan modification
  • 批准号:
    10096439
  • 项目类别:
  • 资助金额:
    $35.62万
  • 财政年份:
    2021
  • 负责人:
    Aimee Shen
  • 依托单位:
Linking Gene Expression Profiles to Cell Fate in Clostridioides difficile Using Time-Lapse Microscopy
  • 批准号:
    10223787
  • 项目类别:
  • 资助金额:
    $21.86万
  • 财政年份:
    2021
  • 负责人:
    Aimee Shen
  • 依托单位:
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