Predoctoral Training Program in Chemistry and Biology

化学与生物学博士前培训项目

• 批准号: 10334217
• 负责人: Yamuna Krishnan
• 金额: $ 31.22万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10334217
• 关键词: Biology; Chemistry; Training Programs; pre-doctoral

PROJECT SUMMARY/ABSTRACT The landscape of biomedical research is changing rapidly due to major technological and conceptual advances, creating new research opportunities and expansion in the scope of occupations while posing challenges for graduate training in quantitative and multidisciplinary science. Furthermore, an emphasis on best practices in graduate education and mentorship has emerged from socioeconomic shifts. To respond to these ongoing developments and the needs of students and the broader society, the Department of Biochemistry & Molecular Biology (BMB) and the Department of Chemistry (Chem) at The University of Chicago propose an interdisciplinary, predoctoral training program directed at the interface of the chemical and biological sciences (CBI) that aims to recruit, educate and train a diverse, new generation of biomedical scholars by deploying new best practices in training, mentoring, and education to promote rigorous cross- disciplinary research while developing quantitative literacy and maintaining depth in the core discipline, thereby preparing them for success in careers that require scientific training. The program benefits from outstanding faculty and students and introduction of new courses in interdisciplinary science. The 25 training faculty consists of twelve faculty with appointments in BMB (one with a joint appointment in Chemistry), ten faculty in Chemistry (one with a joint appointment in BMB), two in the Ben May Department for Cancer Research, and one in Molecular Engineering. Strategies to develop cross-disciplinary training include: (1) satisfactory completion of a core course in Chemical Biology and a breadth course in the department of the other scientific discipline; (2) cross-disciplinary thesis research; (3) participation in a series of monthly meetings throughout the academic year designated as "Integrative Discussions at the Interface of Chemistry & Biology" to gain acquaintance with theoretical concepts and methods; (4) participation in two quarterly meetings focused on advanced chemical tools in biology (ACT-Bio) and biological problems that require chemical solutions (BPRCS); (5) participation in two in two annual half-day events: a CBI Minisymposium and an “in-house” poster retreat; and (6) workshops to promote quantitative literacy and rigor and reproducibility. Participation in a division-wide career development program helps students explore and prepare for different career paths. The broad scope of the interdisciplinary research interests of the faculty strengthened through collaborative research and teaching ensures a wide variety of opportunities for meaningful cross-training. The program will promote excellence in mentorship through more frequent advising, mentoring compacts and required annual faculty mentorship training. Through active participation in pipeline, outreach, and bridge programs, and through participation in graduate admissions and faculty recruitment, program faculty will promote the recruitment and retention of an increasingly diverse scientific community. An external advisory committee and professionally implemented evaluation instruments will guide improvements to the program.

项目总结/摘要 生物医学研究的景观正在迅速变化，由于主要的技术和概念， 进步，创造新的研究机会，扩大职业范围，同时提出 在定量和多学科科学研究生培训的挑战。此外，强调 研究生教育和导师制方面的最佳做法源于社会经济的变化。应对 这些正在进行的发展和学生的需求和更广泛的社会，系 生物化学与分子生物学（BMB）和化学系（Chem）在该大学 芝加哥提出了一个跨学科的，博士前的培训计划，在化学和生物医学的接口， 生物科学（CBI），旨在招募，教育和培训多样化的新一代生物医学 学者通过部署新的最佳实践，在培训，指导和教育，以促进严格的交叉， 学科研究，同时发展定量素养和保持核心学科的深度，从而 为他们在需要科学训练的职业生涯中取得成功做好准备。该计划受益于杰出的 教师和学生，并在跨学科科学新课程的介绍。25名培训教师 由12名教师在BMB任命（一个与化学联合任命），10名教师在 化学（一个与BMB的联合任命），两个在本·梅癌症研究部， 一个是分子工程开展跨学科培训的策略包括：（1）满意 完成化学生物学的核心课程和其他科学部门的广泛课程 学科;（2）跨学科论文研究;（3）参与一系列的月度会议，整个 指定为“化学与生物学界面综合讨论”的学年，以获得 熟悉理论概念和方法;（4）参加两次季度会议，重点关注 先进的生物化学工具（ACT-Bio）和需要化学解决方案的生物问题 （孟加拉国重建和社会事务局）;（5）每年参加两次为期半天的活动：中央调查局的小型专题讨论会和“内部”海报 务虚会;和（6）讲习班，以促进定量识字和严谨性和可重复性。参加某项 全部门的职业发展计划帮助学生探索和准备不同的职业道路。 通过合作加强教师的跨学科研究兴趣的广泛范围 研究和教学确保了有意义的交叉培训的各种机会。该计划将 通过更频繁地提供咨询、签订指导契约和要求每年 教师指导培训。通过积极参与管道、外展和桥梁计划， 通过参与研究生招生和教师招聘，项目教师将促进 招聘和留住日益多样化的科学界。一个外部咨询委员会， 专业执行的评估工具将指导该方案的改进。