Predoctoral Training Program in Chemistry and Biology

化学与生物学博士前培训项目

• 批准号: 10641675
• 负责人: Yamuna Krishnan
• 金额: $ 31.83万
• 依托单位: UNIVERSITY OF CHICAGO
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-07-01 至 2027-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10641675
• 关键词: Biology; Chemistry; Training Programs; pre-doctoral

PROJECT SUMMARY/ABSTRACT The landscape of biomedical research is changing rapidly due to major technological and conceptual advances, creating new research opportunities and expansion in the scope of occupations while posing challenges for graduate training in quantitative and multidisciplinary science. Furthermore, an emphasis on best practices in graduate education and mentorship has emerged from socioeconomic shifts. To respond to these ongoing developments and the needs of students and the broader society, the Department of Biochemistry & Molecular Biology (BMB) and the Department of Chemistry (Chem) at The University of Chicago propose an interdisciplinary, predoctoral training program directed at the interface of the chemical and biological sciences (CBI) that aims to recruit, educate and train a diverse, new generation of biomedical scholars by deploying new best practices in training, mentoring, and education to promote rigorous cross- disciplinary research while developing quantitative literacy and maintaining depth in the core discipline, thereby preparing them for success in careers that require scientific training. The program benefits from outstanding faculty and students and introduction of new courses in interdisciplinary science. The 25 training faculty consists of twelve faculty with appointments in BMB (one with a joint appointment in Chemistry), ten faculty in Chemistry (one with a joint appointment in BMB), two in the Ben May Department for Cancer Research, and one in Molecular Engineering. Strategies to develop cross-disciplinary training include: (1) satisfactory completion of a core course in Chemical Biology and a breadth course in the department of the other scientific discipline; (2) cross-disciplinary thesis research; (3) participation in a series of monthly meetings throughout the academic year designated as "Integrative Discussions at the Interface of Chemistry & Biology" to gain acquaintance with theoretical concepts and methods; (4) participation in two quarterly meetings focused on advanced chemical tools in biology (ACT-Bio) and biological problems that require chemical solutions (BPRCS); (5) participation in two in two annual half-day events: a CBI Minisymposium and an “in-house” poster retreat; and (6) workshops to promote quantitative literacy and rigor and reproducibility. Participation in a division-wide career development program helps students explore and prepare for different career paths. The broad scope of the interdisciplinary research interests of the faculty strengthened through collaborative research and teaching ensures a wide variety of opportunities for meaningful cross-training. The program will promote excellence in mentorship through more frequent advising, mentoring compacts and required annual faculty mentorship training. Through active participation in pipeline, outreach, and bridge programs, and through participation in graduate admissions and faculty recruitment, program faculty will promote the recruitment and retention of an increasingly diverse scientific community. An external advisory committee and professionally implemented evaluation instruments will guide improvements to the program.

项目概要/摘要 由于重大技术和概念的变化，生物医学研究的格局正在迅速变化 进步，创造新的研究机会并扩大职业范围，同时提出 定量和多学科科学研究生培训面临的挑战。此外，还强调 研究生教育和指导的最佳做法源于社会经济的转变。回应 这些持续的发展以及学生和更广泛社会的需求，系 伦敦大学生物化学与分子生物学 (BMB) 和化学系 (Chem) 芝加哥提出了一个跨学科的博士前培训计划，针对化学和化学的界面 生物科学（CBI），旨在招募、教育和培训多元化的新一代生物医学人才 学者们通过在培训、指导和教育方面部署新的最佳实践来促进严格的跨学科研究 学科研究，同时发展定量素养并保持核心学科的深度，从而 为他们在需要科学培训的职业生涯中取得成功做好准备。该计划受益于杰出的 教师和学生以及跨学科科学新课程的介绍。 25名培训师资 包括 12 名在 BMB 任职的教员（其中一名在化学方面联合任职）、10 名在 BMB 任职的教员 化学（一名在 BMB 联合任命），两名在 Ben May 癌症研究部，以及 分子工程专业之一。发展跨学科培训的策略包括：（1）令人满意的 完成化学生物学核心课程和其他科学系的广度课程 纪律; （二）跨学科论文研究； (3) 全程参与一系列月度会议 指定为“化学与生物学交叉点的综合讨论”的学年，以获得 熟悉理论概念和方法； (4) 参加两次季度会议，重点关注 先进的生物学化学工具（ACT-Bio）和需要化学解决方案的生物学问题 （BPRCS）； (5) 参加两次年度半天活动中的两次：CBI 小型研讨会和“内部”海报 撤退; (6) 提高定量素养、严谨性和可重复性的研讨会。参加一个 全部门的职业发展计划帮助学生探索并为不同的职业道路做好准备。 通过合作加强了教师跨学科研究兴趣的广泛范围 研究和教学确保了有意义的交叉培训的各种机会。该计划将 通过更频繁的建议、指导契约和所需的年度指导，促进卓越的指导 师资辅导培训。通过积极参与管道、外展和桥梁项目，以及 通过参与研究生招生和教师招聘，项目教师将促进 招募和保留日益多样化的科学界。外部咨询委员会和 专业实施的评估工具将指导方案的改进。