Center for Neural Circuits in Addiction

成瘾神经回路中心

• 批准号: 10364390
• 负责人: Mark John Thomas
• 金额: $ 16.43万
• 依托单位: UNIVERSITY OF MINNESOTA
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-05-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10364390
• 关键词: Address; Administrative Supplement; Affect; Ambulatory Care; Area; Attitude; Bioethics; Caregivers; Clinical; Complex; Consent; Data; Data Set; Deep Brain Stimulation; Development; Dimensions; Epilepsy; Ethical Issues; Ethicists; Ethics; Family; Funding; Future; Gender; Individual; Intervention; Interview; Light; Mental disorders; Methodology; Methods; Movement Disorders; National Institute of Drug Abuse; Neurosciences; Operative Surgical Procedures; Outpatients; Participant; Patients; Pilot Projects; Policy Maker; Privacy; Public Opinion; Recovery; Research; Residential Treatment; Resistance; Science; Series; Social support; Structure; Surveys; Technology; Treatment outcome; Underrepresented Minority; Work; addiction; cost; evidence base; expectation; experience; fictional works; innovation; interest; neural circuit; neurotechnology; novel; recruit; scale up; social; social stigma; success; tool

PROJECT SUMMARY/ABSTRACT This administrative supplement proposes to examine stakeholder views on deep brain stimulation (DBS) as a potential therapy for treatment-resistant addiction. This proposal extends the neuroscience work being conducted by the NIDA Center for Neural Circuits in Addiction (1P30DA048742-01A1) to address a critical near- term translational barrier: whether neurotechnology therapies like DBS, which are part of the Center's novel, circuit-oriented translational efforts, raise social and ethical concerns among key stakeholders. Work funded by this supplement will develop a critical ethics evidence base for the Center and the field of addiction research. This study will focus on two aims. The first is to conduct qualitative interviews with participants in addiction treatment and recovery about DBS. The study will capture participant's experiences with addiction and explore the ethical dimensions of DBS as a future treatment for addiction. The second aim is to collect both qualitative and quantitative data on perceived social support in addiction. The NIDA Center for Neural Circuits in Addiction aims to have a real-world impact on addiction and addiction treatment, including developing novel treatment interventions, like DBS. This project will both conduct bioethics research to help inform the development of deep brain stimulation in the area of addiction and will develop bioethics capacity through involvement of a bioethics trainee in qualitative interviewing.

项目摘要/摘要 本行政副刊建议审查利益相关者对脑深部刺激(DBS)的看法 治疗难治性成瘾的潜在疗法。这项提议将神经科学的工作扩展到 由NIDA成瘾神经电路中心(1P30DA048742-01A1)进行，以解决关键的近... 术语翻译障碍：神经技术疗法，如DBS，是该中心小说的一部分， 以巡回为导向的翻译努力，在主要利益攸关方中引起了社会和伦理关切。工作经费由 这份补充材料将为该中心和成瘾研究领域建立一个重要的伦理证据基础。 本研究将围绕两个目标展开。一是对成瘾患者进行定性访谈。 关于星展银行的治疗和康复。这项研究将捕捉参与者的成瘾经历并探索 DBS作为未来成瘾治疗方法的伦理层面。第二个目标是收集定性的 以及成瘾患者领悟到的社会支持的量化数据。NIDA成瘾神经回路研究中心 旨在对成瘾和成瘾治疗产生现实影响，包括开发新的治疗方法 干预措施，比如星展银行。该项目将进行生物伦理学研究，以帮助为深部的发展提供信息 在成瘾领域进行脑刺激，并将通过生物伦理学的参与发展生物伦理学能力 定性面试实习生。