Cognitive Neuroscience of Development and Aging (CONDA) Center

发育与衰老认知神经科学 (CONDA) 中心

• 批准号: 10360484
• 负责人: Anna Dunaevsky
• 金额: $ 227.96万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-15 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10360484
• 关键词: Address; Advisory Committees; Aging; Area; Award; Brain; Centers of Research Excellence; Clinical; Cognitive; Collection; Communities; Core Facility; Development; Diabetes Mellitus; Discipline; Disease; Educational workshop; Ensure; Environment; Equipment; Evaluation; Event; Extramural Activities; Faculty; Fellowship; Fellowship Program; Financial Support; Funding; Future; Future Generations; Future Teacher; Goals; Government; Grant; Growth; Hospitals; Human; Infrastructure; Institution; Internships; Journals; Laboratories; Lead; Location; Longevity; Magnetic Resonance Imaging; Medical center; Mentors; Methods; Midwestern United States; Modality; Monitor; NCI Scholars Program; National Institute of General Medical Sciences; Nebraska; Neurologic; Neurosciences; Neurosciences Research; Participant; Pilot Projects; Publishing; Registries; Research; Research Personnel; Research Project Grants; Research Support; Resources; Scientist; Series; Stretching; Structure; Support System; System; Training; United States National Institutes of Health; Universities; Voice; Work; affective neuroscience; base; boys; brain research; career development; cognitive development; cognitive neuroscience; cohort; design; experience; frontier; graduate student; improved; innovation; interest; member; multidisciplinary; neuroimaging; neuroregulation; novel; operation; programs; recruit; research and development; scaffold; tool; training opportunity

Abstract/Summary: Overall Component This application for a Center of Biomedical Research Excellence (COBRE) would initiate a formal Center to lead, support, and expand neuroimaging and clinical cognitive neuroscience research in Nebraska, with an emphasis on lifespan development. It is an opportune moment for human neuroscience research in the Omaha community, regionally, and across the world, with many new research tools and government initiatives intended to illuminate the next frontier of biomedicine. The proposed Cognitive Neuroscience of Development and Aging (CONDA) Center will provide critical resources and support to faculty from four institutions: the University of Nebraska Medical Center (UNMC), the Boys Town National Research Hospital, the University of Nebraska – Omaha, and Creighton University. The Administrative Core of the CONDA Center will be housed at UNMC, which is less than two miles from each of the other institutions, and will be comprised of Training, Evaluation, Engagement, Administration, and Mentoring areas (i.e., the TEEAM Core). The new CONDA Center will also include a state- of-the-art Neuroimaging Acquisition and Analysis Core, as well as extensive support for four primary COBRE research projects led by a promising group of NIH-defined early-stage investigators. Upon initiation of the Center, the TEEAM Core would immediately implement a series of new programs that are designed to develop human cognitive neuroscience on the CONDA Campus and across the region. The TEEAM Core would also rapidly implement a comprehensive research support structure that includes the Neuroimaging Core facility, training opportunities, pilot projects and mini-grants programs, a new seminar series, postdoctoral fellowships, intern- ships for growing temporary and long-term laboratory staffing, and a participant registry to enhance recruitment. In parallel, the TEEAM Core would promote the successful launch of the primary COBRE research projects and, through a mentoring network approach, implement a career development and evaluation support system to monitor progress and ensure Junior PIs and their mentoring teams reach critical milestones. As per the new research core, the Neuroimaging Acquisition and Analysis Core facility would be the only core dedicated to human brain research in the state of Nebraska, and would provide regional scientists with state-of-the-art tools for neuroimaging and neuromodulation, including research-dedicated MRI and MEG systems. The new Center would also receive exceptional institutional support, including financial support for CONDA programs, major equipment expenses, and Core staffing. The overall CONDA team includes an established group of PIs in neuro- imaging, brain dynamics, aging, and brain and cognitive development, as well as a strong cohort of emerging junior investigators using innovative cognitive and affective neuroscience methods to address major questions in human neuroscience across the lifespan. These junior scientists were all hired in the past three years, and this new wealth of concentrated local expertise has primed us for a trajectory of accelerated development of neuro- science and neuroimaging toward national prominence, an aim for which the new CONDA Center will be integral.

摘要/总结：总体组成部分 生物医学研究卓越中心（COBRE）的这项申请将启动一个正式的中心来领导， 支持并扩大内布拉斯加州的神经影像和临床认知神经科学研究，重点是 关于生命周期的发展。这是奥马哈社区人类神经科学研究的好时机， 在区域和世界范围内，许多新的研究工具和政府举措旨在阐明 生物医学的下一个前沿。拟议的发展和衰老认知神经科学（CONDA） 该中心将为来自四个机构的教师提供关键资源和支持： 内布拉斯加大学 医疗中心 (UNMC)、男孩镇国家研究医院、内布拉斯加大学奥马哈分校，以及 克赖顿大学。 CONDA 中心的行政核心将设在 UNMC，面积小于 距其他机构两英里，将包括培训、评估、参与、 管理和指导领域（即 TEEAM 核心）。新的 CONDA 中心还将包括一个州立- 最先进的神经影像采集和分析核心，以及对四种主要 COBRE 的广泛支持 由 NIH 定义的一群有前途的早期研究人员领导的研究项目。中心成立后， TEEAM Core 将立即实施一系列旨在开发人类能力的新计划 CONDA 校园和整个地区的认知神经科学。 TEEAM Core 也将迅速 实施全面的研究支持结构，包括神经影像核心设施、培训 机会、试点项目和小额赠款计划、新的研讨会系列、博士后奖学金、实习生 用于增加临时和长期实验室人员配备的船舶，以及用于加强招募的参与者登记册。 与此同时，TEEAM 核心将促进主要 COBRE 研究项目的成功启动，并且， 通过导师网络方式，实施职业发展和评估支持系统 监控进展并确保初级 PI 及其指导团队达到关键里程碑。根据新的 研究核心，神经影像采集和分析核心设施将是唯一致力于 在内布拉斯加州进行人脑研究，将为地区科学家提供最先进的工具 用于神经成像和神经调节，包括研究专用 MRI 和 MEG 系统。新中心 还将获得特殊的机构支持，包括对 CONDA 项目、主要项目的财政支持 设备费用和核心人员配置。整个 CONDA 团队包括一组神经领域的既定 PI 成像、大脑动力学、衰老、大脑和认知发展，以及强大的新兴群体 初级研究人员使用创新的认知和情感神经科学方法来解决重大问题 人类神经科学的整个生命周期。这些初级科学家都是近三年来聘用的，而这 集中的本地专业知识的新财富为我们加速发展神经系统奠定了基础 科学和神经影像学在全国范围内取得突出地位，新的 CONDA 中心将成为这一目标的组成部分。