Cognitive Neuroscience of Development and Aging (CoNDA) Center Supplement

发育与衰老认知神经科学 (CoNDA) 中心增刊

• 批准号: 10400412
• 负责人: Anna Dunaevsky
• 金额: $ 25万
• 依托单位: UNIVERSITY OF NEBRASKA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-03-15 至 2025-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10400412
• 关键词: Address; Aging; Area; Behavior assessment; Brain; Centers of Research Excellence; Clinical; Communities; Consultations; Core Facility; Data; Data Analyses; Development; Ensure; Equipment; Evaluation; Faculty; Fellowship; Financial Support; Government; Grant; High Performance Computing; Hospitals; Human; Image; Individual; Information Technology; Institution; Internships; Investigation; Laboratories; Lead; Longevity; Magnetic Resonance Imaging; Medical center; Mentors; Methods; Mission; Monitor; National Institute of General Medical Sciences; Nebraska; Neurosciences; Neurosciences Research; Participant; Performance; Pilot Projects; Registries; Reproducibility; Research; Research Personnel; Research Project Grants; Research Support; Resources; Scientist; Series; Software Tools; Structure; Support System; System; Training; United States National Institutes of Health; Universities; affective neuroscience; boys; brain research; career development; cluster computing; cognitive ability; cognitive development; cognitive neuroscience; cohort; computer cluster; computerized data processing; computing resources; data resource; design; digital imaging; frontier; innovation; neuroimaging; neuroregulation; programs; recruit; tool; training opportunity

This application for a Center of Biomedical Research Excellence (COBRE) would initiate a formal Center to lead, support, and expand neuroimaging and clinical cognitive neuroscience research in Nebraska, with an emphasis on lifespan development. It is an opportune moment for human neuroscience research in the Omaha community, regionally, and across the world, with many new research tools and government initiatives intended to illuminate the next frontier of biomedicine. The proposed Cognitive Neuroscience of Development and Aging (CONDA) Center will provide critical resources and support to faculty from four institutions: the University of Nebraska Medical Center (UNMC), the Boys Town National Research Hospital, the University of Nebraska – Omaha, and Creighton University. The Administrative Core of the CONDA Center will be housed at UNMC, which is less than two miles from each of the other institutions, and will be comprised of Training, Evaluation, Engagement, Administration, and Mentoring areas (i.e., the TEEAM Core). The new CONDA Center will also include a state- of-the-art Neuroimaging Acquisition and Analysis Core, as well as extensive support for four primary COBRE research projects led by a promising group of NIH-defined early-stage investigators. Upon initiation of the Center, the TEEAM Core would immediately implement a series of new programs that are designed to develop human cognitive neuroscience on the CONDA Campus and across the region. The TEEAM Core would also rapidly implement a comprehensive research support structure that includes the Neuroimaging Core facility, training opportunities, pilot projects and mini-grants programs, a new seminar series, postdoctoral fellowships, intern- ships for growing temporary and long-term laboratory staffing, and a participant registry to enhance recruitment. In parallel, the TEEAM Core would promote the successful launch of the primary COBRE research projects and, through a mentoring network approach, implement a career development and evaluation support system to monitor progress and ensure Junior PIs and their mentoring teams reach critical milestones. As per the new research core, the Neuroimaging Acquisition and Analysis Core facility would be the only core dedicated to human brain research in the state of Nebraska, and would provide regional scientists with state-of-the-art tools for neuroimaging and neuromodulation, including research-dedicated MRI and MEG systems. The new Center would also receive exceptional institutional support, including financial support for CONDA programs, major equipment expenses, and Core staffing. The overall CONDA team includes an established group of PIs in neuro- imaging, brain dynamics, aging, and brain and cognitive development, as well as a strong cohort of emerging junior investigators using innovative cognitive and affective neuroscience methods to address major questions in human neuroscience across the lifespan.

生物医学卓越研究中心 (COBRE) 的这项申请将启动一个正式的项目 领导、支持和扩展神经影像和临床认知神经科学研究的中心 在内布拉斯加州，重点是终身发展。这对人类来说是一个有利时机 奥马哈社区、地区和世界范围内的神经科学研究 新的研究工具和政府举措旨在阐明下一个前沿领域 生物医学。拟建的发育与衰老认知神经科学（CONDA）中心 将为四个机构的教师提供关键资源和支持： 内布拉斯加州医疗中心 (UNMC)、男孩城国家研究医院、内布拉斯加州大学 内布拉斯加州-奥马哈和克赖顿大学。 CONDA 中心的行政核心将 位于 UNMC，距离其他机构均不到两英里，并且将 包括培训、评估、参与、管理和指导领域（即 TEEAM 核心）。新的 CONDA 中心还将包括最先进的神经影像设备 采集和分析核心，以及对四个主要 COBRE 研究的广泛支持 由 NIH 定义的一群有前途的早期研究人员领导的项目。启动后 中心，TEEAM Core 将立即实施一系列新计划，这些计划是 旨在在 CONDA 校园和整个世界范围内发展人类认知神经科学 地区。 TEEAM核心还将快速实施全面的研究支持 结构，包括神经影像核心设施、培训机会、试点项目和 小额赠款计划、新的研讨会系列、博士后奖学金、成长实习 临时和长期实验室人员配置，以及用于加强招募的参与者登记册。在 与此同时，TEEAM Core 将促进 COBRE 主要研究的成功启动 项目，并通过指导网络方法实施职业发展和 评估支持系统，用于监控进展并确保初级 PI 及其指导团队 达到关键里程碑。根据新的研究核心，神经影像采集和 分析核心设施将是该州唯一致力于人脑研究的核心设施 内布拉斯加州，将为地区科学家提供最先进的神经成像工具和 神经调节，包括研究专用 MRI 和 MEG 系统。新中心将 还获得特殊的机构支持，包括对 CONDA 计划的财政支持， 主要设备费用和核心人员配置。整个 CONDA 团队包括一个已建立的 神经成像、大脑动力学、衰老、大脑和认知发展领域的 PI 组，如 以及一群新兴的初级研究人员使用创新的认知和情感 神经科学方法来解决人类神经科学在整个生命周期中的主要问题。