Administrative Core

项目摘要/摘要 管理核心-核心A 很少有学术中心专注于翻译新的疗法来保护或恢复听力和 前庭功能。在本Cobre的第一阶段，行政核心的目标是提供主题 翻译听证中心建立可持续发展的方向和科学基础设施 克雷顿大学的多学科研究项目，获得国内和国际认可。我们会 将教师发展与强有力的指导和优秀的创新试点项目相结合， 具有战略规划和综合评价，纳入健全的行政结构。具体目标 行政核心的目标是： 1)提供中心的财务和行政管理，包括财务和人事管理 在处理各种事项、协调会议、问责制、增强网上能力和传播成果方面，这方面的工作取得了进展。 2)培养强大的中心调查人员，获得同行评审的拨款，以启动长期的研究生涯 验证和翻译保存或恢复听力和前庭功能的新疗法。我们 将提供密集的指导和访问研究核心，并提供协作机会，并建立 一大批以中心为中心的调查人员。 3)建立一个优秀的试点项目计划，以吸引新的调查人员进入该中心，并提供准入 到我们的研究核心，使他们能够产生可靠的试点数据，以获得外部研究拨款。 4)通过四个次级目标为成功和可持续发展提供领导：a)招聘优秀的新员工 向中心提供研究人员和受训人员；b)加强对中心的研究资助，c)促进 通过发展研究核心服务收费结构增强中心的财务独立性 (D)指导中心的长期可持续性战略规划；以及 5)制定评估计划，以评估中心活动的绩效和结果，以确定和 实施改进措施以加强翻译听证中心的影响力。 一个专门的行政核心，以创造一个支持性的科学环境，将使中心能够 可持续地招募、指导和留住足够数量的研究人员，以翻译候选耳疗 为临床研究保留或恢复听力和前庭功能。

PROJECT SUMMARY/ABSTRACT Administrative Core – Core A There are few academic centers that focus on translating novel therapeutics to preserve or restore hearing and vestibular function. In Phase I of this COBRE, the goal of the Administrative Core is to provide the thematic direction and scientific infrastructure for the Translational Hearing Center to establish a sustainable multidisciplinary research program at Creighton University with national and international recognition. We will integrate faculty development with strong mentoring and an excellent and innovative pilot project program, along with strategic planning and comprehensive evaluation, into a robust administrative structure. The Specific Aims of the Administrative Core are to: 1) Provide fiscal and administrative management of the Center including management of fiscal and personnel matters, coordination of meetings, accountability, enhanced online capabilities, and dissemination of results. 2) Develop strong Center investigators that obtain peer-reviewed grants to launch long-term research careers validating and translating novel therapeutics that preserve or restore hearing and vestibular function. We will provide intensive mentoring and access to Research Cores with opportunities for collaboration, and build a critical mass of Center-focused investigators. 3) Establish an excellent Pilot Project Program to attract new investigators to the Center, and provide access to our Research Cores, to empower them to generate sound pilot data to obtain extramural research grants. 4) Provide leadership for success and sustainability through four sub-aims to: a) recruit excellent new investigators and trainees to the Center; b) strengthen research funding of the Center, c) promote the Center’s financial independence by developing fee structures for Research Core services to enhance Center sustainability, and d) guide strategic planning for long-term sustainability of the Center; and 5) Develop an evaluation program to assess performance and outcomes of Center activities to identify and implement improvements to strengthen the impact of the Translational Hearing Center. A dedicated Administrative Core to create a supportive scientific environment will enable the Center to sustainably recruit, mentor and retain a critical mass of investigators to translate candidate ototherapeutics that preserve or restore hearing and vestibular function towards clinical studies.