Alterations and Renovations

改建和翻新

• 批准号: 10090987
• 负责人: Peter Stephen Steyger
• 金额: $ 12.78万
• 依托单位: CREIGHTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2021
• 资助国家: 美国
• 起止时间: 2021-03-05 至 2026-01-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10090987
• 关键词: Acids; Air; Auditory; Auditory Brainstem Responses; Award; Centers of Research Excellence; Chemicals; Complex; Computers; Core Facility; Drug Delivery Systems; Duct (organ) structure; Environment; Equipment; Floor; Health Services Research; Hearing; Hearing Tests; Hospitals; Image; Institution; Laboratories; Light; Lighting; Medical center; Microscope; Modernization; Nebraska; Pharmaceutical Chemistry; Research; Research Personnel; Research Project Grants; Savings; Services; Side; Solid; System; Technology; Testing; Therapeutic; Translational Research; Universities; Visual; boys; chemical synthesis; drug discovery; exhaust; foot; hearing impairment; operation; otoacoustic emission

ALTERATION & RENOVATION Project Summary/Abstract The Translational Hearing Center (THC) has established two functional cores: The Drug Discovery & Delivery Core (DDDC) and Auditory & Vestibular Technology Core (AVTC) to promote and enhance translational research on therapeutics for hearing loss. Currently all core facilities and equipment are located in close proximity to or within the Creighton University Core Facilities in the Criss I/II/III building complex, with additional satellite AVTCs located in neighboring institutions: University of Nebraska Medical Center (UNMC) and Boys Town National Research Hospital (BTNRH). To further empower our services for the Research Project Leaders (RPLs) and Center Investigators, we plan to align our facilities with our strength by creating new laboratory spaces through renovation of existing laboratories within first year of the COBRE award. To facilitate efficient chemical synthesis and analysis and facilitate new advanced imaging, we seek to renovate medicinal chemistry laboratory Criss II 326 and a new space for auditory hearing test laboratory Criss I 304. With these renovation projects completed, THC will have new, centralized laboratories for each core. These can be easily further expanded and integrated into the Creighton University Core Facilities. These will significantly enhance our services outlined in our proposal.

改造与翻新 项目总结/摘要 翻译听力中心（THC）建立了两个功能核心： 发现和交付核心（DDDC）和听觉和前庭技术核心（AVTC）， 促进和加强听力损失治疗的转化研究。目前，所有核心 设施和设备位于靠近或在克雷顿大学核心 Criss I/II/III建筑群内的设施，以及位于 邻近机构：内布拉斯加大学医学中心（UNMC）和男孩城 国家研究医院（BTNRH）。进一步加强我们为研究项目提供的服务 领导者（RPL）和中心调查员，我们计划通过以下方式使我们的设施与我们的实力保持一致 在第一年内通过翻新现有实验室创造新的实验室空间 COBRE奖。为了促进有效的化学合成和分析， 先进的成像，我们寻求翻新药物化学实验室克里斯II 326和一个新的 空间听觉听力测试实验室克里斯我304。随着这些改造项目的完成， THC将为每个核心建立新的集中实验室。这些可以很容易地进一步 扩大并融入克雷顿大学核心设施。这些将大大 加强我们在提案中概述的服务。