Administrative Core

项目概要/摘要 行政核心 – 核心 A 很少有学术中心专注于转化新疗法以保留或恢复听力和 前庭功能。在 COBRE 的第一阶段，行政核心的目标是提供主题 为翻译听力中心建立可持续发展的方向和科学基础设施 克赖顿大学的多学科研究项目获得国内和国际认可。我们会 将教师发展与强有力的指导以及优秀和创新的试点项目计划相结合， 通过战略规划和综合评估，形成健全的行政架构。具体目标 行政核心的职责是： 1) 提供中心的财务和行政管理，包括财务和人事管理 务、会议协调、问责制、增强的在线能力和成果传播。 2) 培养强大的中心研究人员，获得同行评审的资助，开展长期的研究生涯 验证和转化保留或恢复听力和前庭功能的新疗法。我们 将提供深入的指导和研究核心的机会以及合作机会，并建立 大量以中心为中心的调查人员。 3) 建立一个优秀的试点项目计划，吸引新的研究人员到中心，并提供访问 到我们的研究核心，使他们能够生成可靠的试点数据以获得校外研究资助。 4) 通过四个子目标为成功和可持续发展提供领导力： a) 招募优秀的新人 中心的调查员和实习生； b) 加强中心的研究经费， c) 促进 通过制定研究核心服务的收费结构来增强中心的财务独立性 可持续性，以及 d) 指导中心长期可持续性的战略规划；和 5) 制定评估计划来评估中心活动的绩效和成果，以确定和 实施改进以增强翻译听力中心的影响。 一个专门的行政核心来创造一个支持性的科学环境将使该中心能够 持续招募、指导和留住足够数量的研究人员来翻译候选耳科治疗药物 保留或恢复听力和前庭功能以进行临床研究。

PROJECT SUMMARY/ABSTRACT Administrative Core – Core A There are few academic centers that focus on translating novel therapeutics to preserve or restore hearing and vestibular function. In Phase I of this COBRE, the goal of the Administrative Core is to provide the thematic direction and scientific infrastructure for the Translational Hearing Center to establish a sustainable multidisciplinary research program at Creighton University with national and international recognition. We will integrate faculty development with strong mentoring and an excellent and innovative pilot project program, along with strategic planning and comprehensive evaluation, into a robust administrative structure. The Specific Aims of the Administrative Core are to: 1) Provide fiscal and administrative management of the Center including management of fiscal and personnel matters, coordination of meetings, accountability, enhanced online capabilities, and dissemination of results. 2) Develop strong Center investigators that obtain peer-reviewed grants to launch long-term research careers validating and translating novel therapeutics that preserve or restore hearing and vestibular function. We will provide intensive mentoring and access to Research Cores with opportunities for collaboration, and build a critical mass of Center-focused investigators. 3) Establish an excellent Pilot Project Program to attract new investigators to the Center, and provide access to our Research Cores, to empower them to generate sound pilot data to obtain extramural research grants. 4) Provide leadership for success and sustainability through four sub-aims to: a) recruit excellent new investigators and trainees to the Center; b) strengthen research funding of the Center, c) promote the Center’s financial independence by developing fee structures for Research Core services to enhance Center sustainability, and d) guide strategic planning for long-term sustainability of the Center; and 5) Develop an evaluation program to assess performance and outcomes of Center activities to identify and implement improvements to strengthen the impact of the Translational Hearing Center. A dedicated Administrative Core to create a supportive scientific environment will enable the Center to sustainably recruit, mentor and retain a critical mass of investigators to translate candidate ototherapeutics that preserve or restore hearing and vestibular function towards clinical studies.