Stephenson Cancer Center - Cancer Center Support Grant

家长奖摘要 俄克拉荷马大学的斯蒂芬森癌症中心(SCC)继续增长， 在NCI癌症中心支持赠款(CCSG)资助的第三个年头成熟。作为该州的 只有NCI指定的癌症中心，SCC肩负着根除癌症的重要使命 俄克拉荷马州及其他地区：1)提供最高水平的研究驱动型患者 中心关怀；2)将新发现转化为临床和社区环境；3)参与 社区和解决集水区普遍存在的癌症问题；以及4)培训 下一代癌症研究人员和健康专业人员。这项任务特别是 在俄克拉荷马州至关重要，该州经年龄调整后的癌症死亡率(177.3%)位居第四 100,000)在所有州(CDC)。推进这一使命的努力是以五年为指导的 战略计划(2018-22年)，并得到以下方面的重大机构承诺的支持 大学和州立大学。 SCC目前有131名成员(71名正式成员和60名准成员)，代表32个不同的 俄勒冈大学健康科学中心(OUHSC)和俄勒冈大学诺曼分校的学术部门 校园。这些癌症中心成员在Peer杂志上发表了295篇以癌症为重点的出版物 审阅了期刊。其中，22%涉及程序内部，9%涉及程序间 合作。值得注意的是，这两个百分比在2020年可能都大幅下降 反映了新冠肺炎时代合作的障碍。SCC成员出版物 继续反映与其他机构的科学家的重大合作(80%)，并在 这一类别，在NCI指定的其他癌症中心(50%)。SCC的研究仍在继续 为了反映出对俄克拉何马州癌症问题的强烈关注，俄克拉何马州是SCC的集水区， 尤其是该州大量的印第安人和农村人口，他们经历了 更高的癌症发病率和死亡率。 SCC继续在临床研究方面处于全国领先地位。在本报告所述期间， SCC有666项应计项目用于介入治疗试验，634项应计项目用于非介入治疗试验 治疗试验。在NCI的国家临床中心，SCC仍然是最大的积累场所 试验网络(NCTN)，在2020财年招募288名患者参加国家团体试验。在.期间 在本报告所述期间，SCC是一个获奖财团申请的牵头合作伙伴 (UM1CA186689)，用于NCI实验治疗临床试验网络(ETCTN)， 从而实现SCC 2018-22年战略规划的主要目标。SCC中的活动 教育、培训和职业提升(ETCE)核心显著增长， 突出的是同行审查的培训资金继续增加(见上文)。SCC的 社区外联和接洽(COE)核心正在继续增加容量并采取 在促进和协调以SCC集水区为重点的研究方面发挥领导作用。SCC 继续是全国进行基于社区的部落研究的首选网站 合作伙伴解决#年美洲印第安人的高癌症发病率和死亡率 州政府。

Parent Award ABSTRACT The Stephenson Cancer Center (SCC) at the University of Oklahoma continued to grow and mature during its third year of NCI Cancer Center Support Grant (CCSG) funding. As the state's only NCI-Designated Cancer Center, the SCC has a critical mission of eliminating cancer in Oklahoma and beyond through: 1) providing the highest level of research-driven, patient centered care; 2) translating novel discoveries to the clinic and community settings; 3) engaging the community and addressing cancer problems prevalent in the catchment area; and 4) training the next generation of cancer researchers and health professionals. This mission is especially critical in Oklahoma, which has the fourth highest age-adjusted cancer death rate (177.3 per 100,000) among all states (CDC). Efforts to advance this mission are guided by a five-year Strategic Plan (2018-22) and supported by significant institutional commitments on the part of the University and State. The SCC currently has 131 members (71 Full and 60 Associate), representing 32 different academic departments at the OU Health Sciences Center (OUHSC) and OU Norman campuses. These cancer center members published 295 cancer-focused publications in peer reviewed journals. Of these, 22% involved Intra-Programmatic and 9% Inter-Programmatic collaborations. Notably, both of these percentages dipped significantly in 2020, perhaps reflective of obstacles to collaborating in the era of COVID-19. SCC member publications continued to reflect significant collaboration with scientists at other institutions (80%) and, within that category, at other NCI-Designated Cancer Centers (50%). Research at the SCC continues to reflect a strong focus on cancer problems prevalent in Oklahoma, the SCC's catchment area, and especially the state's large American Indian and rural populations that experience significantly higher cancer incidence and mortality rates. The SCC continues to be a national leader in clinical research. During the reporting period, the SCC had 666 accruals to interventional treatment trials and 634 accruals to interventional non- treatment trials. The SCC continues to be the top accruing site in the NCI's National Clinical Trials Network (NCTN), enrolling 288 patients to National Group trials in CY2020. During the reporting period, the SCC was a lead partner in an awarded consortium application (UM1CA186689) for the NCI Experimental Therapeutics Clinical Trials Network (ETCTN), thereby achieving a primary goal in the SCC's 2018-22 Strategic Plan. Activities in the SCC's Education, Training and Career Enhancement (ETCE) Core have grown significantly, highlighted by a continued increase in peer-reviewed training funding (see above). The SCC's Community Outreach and Engagement (COE) Core is continuing to add capacity and take a lead role in promoting and coordinating research focused on the SCC catchment area. The SCC continues to be a premier site nationally for conducting community-based research with tribal partners to address the high cancer incidence and mortality rates among American Indians in the state.