Increasing physical activity among breast cancer survivors: Use of the ORBIT Model to refine and test a novel approach to exercise promotion based on affect-regulation
增加乳腺癌幸存者的体力活动:使用 ORBIT 模型完善和测试基于情感调节的运动促进新方法
基本信息
- 批准号:10376775
- 负责人:
- 金额:$ 17.78万
- 依托单位:
- 依托单位国家:美国
- 项目类别:
- 财政年份:2021
- 资助国家:美国
- 起止时间:2021-04-01 至 2026-03-31
- 项目状态:未结题
- 来源:
- 关键词:AccelerometerAccountingAddressAdherenceAdverse effectsAffectAffectiveAftercareAmericanArousalAwardBehaviorBehavior TherapyBehavioralBreast Cancer Risk FactorBreast Cancer survivorBreast Cancer survivorshipCancer SurvivorCancer SurvivorshipClinicalClinical Trials DesignConsultationsDataData AnalysesData CollectionDevelopmentDiagnosisDoctor of PhilosophyEcological momentary assessmentExerciseFatigueFeelingFibrinogenGeneral PopulationGoalsGuidelinesHealth BenefitHealth behaviorIndividualInterventionIntervention TrialInterviewInvestigationK-Series Research Career ProgramsKnowledgeLightLongitudinal StudiesMalignant NeoplasmsMeasuresMedical centerMentorsMethodsModelingModificationObesityOncologyOutcomeParticipantPersonsPhasePhysical FunctionPhysical activityPositioning AttributeProtocols documentationPsychologistPublic HealthRandomizedRandomized Clinical TrialsRegulationResearchResearch PersonnelRisk FactorsSamplingScienceScientistSports MedicineStrenuous ExerciseStructureSurveysSurvivorsTestingTimeTrainingTreatment-Related CancerVariantWorkadherence ratearmbasecancer diagnosiscancer recurrencecareercareer developmentcollegedeconditioningdesignexercise prescriptionexercise regimenfollow-uphealth related quality of lifehedonicinnovationmalignant breast neoplasmmethod developmentmodifiable riskmortalitymotivated behaviornovel strategiespatient orientedphysical conditioningphysical inactivitypleasurepost interventionpreferenceresponsesatisfactionskillsstandard of caretherapy development
项目摘要
PROJECT SUMMARY/ABSTRACT
The goal of this K08 Mentored Clinical Scientist Research Career Development Award is to prepare the
candidate for an independent research career
Breast cancer survivors who exercise regularly
in behavioral oncology and health behavior intervention science.
post-cancer diagnosis are less likely to die from cancer and even
modest increases in physical activity (≥
related mortality. However, longitudinal studies show significant declines in exercise engagement during the 12-
15 minutes/week) yield clinically meaningful reductions in breast cancer-
months post-diagnosis, with most breast cancer survivors never fully returning to pre-diagnosis activity levels.
The candidate proposes an innovative approach, based on affect-regulation, to addressing physical inactivity as
a public health risk factor negatively impacting breast cancer survivorship. The training and mentoring plan is
designed to provide knowledge and skills in (1) early-phase intervention development, (2) intensive longitudinal
data collection and analysis methods, (3) randomized clinical trial design, and (4) professional development. The
proposed research will refine an affect-regulated exercise prescription strategy (Affect-Rx) for use with physically
inactive breast cancer survivors (Aim 1), test for proof-of-concept the effect of Affect-Rx on clinically meaningful
moderate-vigorous physical activity participation post-intervention, operationalized as ≥
90 mins/week
(Aim 2),
and quantify the strength of within-person associations between affective factors and total physical activity (Aim
3). The candidate will use the milestones for early-phase intervention development established by the Obesity-
Related Behavioral Intervention Trials (ORBIT)
two studies. In both studies, participants’ daily
Model to guide the methods and outcomes to be tested across
affective feeling states and physical activity will be measured
using ecological momentary assessment (EMA) and accelerometry at baseline and 2-, 6- and 12-weeks follow-
up. The Affect-Rx strategy will be refined for acceptability in Study 1 (N = 20) and tested (with refinements) in
Study 2 (N = 60). In consultation with her team of mentors and scientific advisors, the candidate will use the
training, the results of the research, and the ORBIT intervention development framework to systematically guide
the next steps in this affect-based physical activity promotion line of work and submit her first R01 proposal.
项目总结/摘要
这个K 08指导临床科学家研究职业发展奖的目标是准备
独立研究生涯的候选人
定期锻炼的乳腺癌幸存者
在行为肿瘤学和健康行为干预科学方面。
癌症后诊断不太可能死于癌症,
体力活动适度增加(≥
相关死亡率。然而,纵向研究显示,在12- 18岁期间,
15分钟/周)产生临床上有意义的减少乳腺癌-
大多数乳腺癌幸存者从未完全恢复到诊断前的活动水平。
候选人提出了一种创新的方法,基于影响调节,以解决身体活动不足,
一个对乳腺癌生存率产生负面影响的公共卫生风险因素。培训和指导计划是
旨在提供以下方面的知识和技能:(1)早期干预发展,(2)密集的纵向
数据收集和分析方法,(3)随机临床试验设计,(4)专业发展。的
拟议的研究将完善一种受影响的运动处方策略(Affect-Rx),
非活动性乳腺癌幸存者(目标1),检测Affect-Rx对临床有意义的
干预后参与中度-剧烈体力活动,操作为≥
90分钟/周
(Aim 2)、
并量化情感因素和总体力活动之间的人内关联强度(目的
3)。候选人将使用肥胖症研究所建立的早期干预发展里程碑-
相关行为干预试验(ORBIT)
两项研究。在这两项研究中,参与者每天
模型,以指导方法和结果进行测试,
将测量情感状态和身体活动
在基线和2周、6周和12周后使用生态瞬时评估(EMA)和加速度计-
起来将在研究1(N = 20)中对Affect-Rx策略的可接受性进行细化,并在
研究2(N = 60)。在与她的导师和科学顾问团队协商后,候选人将使用
培训、研究成果和ORBIT干预开发框架,
在这个基于影响的身体活动促进工作线的下一步,并提交她的第一个R 01提案。
项目成果
期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
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{{ truncateString('Courtney Joyce Stevens', 18)}}的其他基金
Increasing physical activity among breast cancer survivors: Use of the ORBIT Model to refine and test a novel approach to exercise promotion based on affect-regulation
增加乳腺癌幸存者的体力活动:使用 ORBIT 模型完善和测试基于情感调节的运动促进新方法
- 批准号:
10191166 - 财政年份:2021
- 资助金额:
$ 17.78万 - 项目类别:
Increasing physical activity among breast cancer survivors: Use of the ORBIT Model to refine and test a novel approach to exercise promotion based on affect-regulation
增加乳腺癌幸存者的体力活动:使用 ORBIT 模型完善和测试基于情感调节的运动促进新方法
- 批准号:
10593920 - 财政年份:2021
- 资助金额:
$ 17.78万 - 项目类别:
Mechanisms of exercise maintenance: Cancer prevention in healthy older women
运动维持机制:健康老年女性的癌症预防
- 批准号:
8780387 - 财政年份:2013
- 资助金额:
$ 17.78万 - 项目类别:
Mechanisms of exercise maintenance: Cancer prevention in healthy older women
运动维持机制:健康老年女性的癌症预防
- 批准号:
8591136 - 财政年份:2013
- 资助金额:
$ 17.78万 - 项目类别:
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