LEAP Administrative Core

1.摘要 “早期精神病实验室”中心的行政核心，又名。LEAP将支持创建 在马萨诸塞州的三个主要的首发精神病诊所和 组建一个由领先研究人员组成的跨学科团队。LEAP中心致力于T2翻译 精神病首次发作的研究，包括分析专业护理的影响，广泛的多模式 纵向数据收集、预测和比较有效性研究，以更好地了解 患者结局和治疗效果的异质性。行政核心将服务于中心的目标 通过促进定期沟通，促进学科之间的协同作用，支持培训机会， 和试点项目，传播中心活动信息，组织利益相关者小组， 对中心本身进行评估。核心将由中心负责人Öngür博士、Hsu博士和 Hernan，并由中心管理员提供支持。核心有四个目标。首先，它将监督和协调 所有对中心运作至关重要的活动，包括维护监管和合同 义务，预算和分包合同的管理，与学术，州和联邦机构的互动， 完成报告要求，支持中心各部门之间的定期沟通，以及 促进和跟踪合作。第二，核心将监督和协调治理结构 包括指导委员会、管理委员会、数据管理和访问委员会、试点项目委员会和培训委员会 在中心内。第三，它将管理征求，审查，资助，监测和报告的行为 平均每年两个R03级试点项目。第四，行政核心将协调和 管理与各种利益相关者的接触，包括患者和家庭团体，国家和 国家政策制定者，支付者，以及一个由高级科学专家组成的小组。核心还将支持 通过会议和短期课程、访问学者系列，传播中心的活动和进展， 临床病例会议、方案和软件，以及一个旨在为公众服务的网站。 最后，行政核心将跟踪中心绩效的客观指标， 咨询委员会会议（由精神病学研究内外的高级研究人员组成 该委员会将对中心的进展情况进行评估，并提出改进建议），并定期召开 中心的教师小组和利益相关者委员会的会议。总的来说，核心活动是 旨在确保LEAP中心成为一个统一的整体，大于其各部分的总和。

1. Abstract The Administrative Core for the “Laboratory in Early Psychosis” Center, a.k.a. LEAP, will support the creation of a research consortium spanning three major first episode psychosis clinics in Massachusetts and the formation of a transdisciplinary team of leading researchers. The LEAP Center is dedicated to T2 translational research in first episode psychosis, including analysis of the impact of specialized care, extensive multimodal longitudinal data collection, and prediction and comparative effectiveness research to better understand heterogeneity in patient outcomes and treatment effects. The Administrative Core will serve the Center’s goals by facilitating regular communication, fostering synergy among disciplines, supporting training opportunities and pilot projects, disseminating information on Center activities, organizing stakeholder panels, and overseeing evaluation of the Center itself. The Core will be led by the Center Leads Drs. Öngür, Hsu, and Hernan, and supported by a Center Administrator. The Core has four aims. First, it will oversee and coordinate all activities essential to the functioning of the Center, including maintenance of regulatory and contractual obligations, management of budgets and subcontracts, interacting with academic, state, and federal agencies, completion of reporting requirements, supporting regular communication between Center elements, and fostering and tracking collaborations. Second, the Core will oversee and coordinate governance structures including the Steering, Manuscript, Data Management and Access, Pilot Project, and Training committees within the Center. Third, it will manage the solicitation, review, funding, monitoring, and reporting of the conduct of an average of two R03-level pilot projects each year. And fourth, the Administrative Core will coordinate and manage engagement with a diverse array of stakeholders including patient and family groups, national and state policy makers, payers, as well as a panel of senior scientific experts. The Core will also support dissemination of Center activities and advances through conferences and short courses, visiting scholar series, clinical case conferences, protocols and software, as well as a website intended to serve the general public. Finally, the Administrative Core will track objective metrics of Center performance and convene annual meetings of the Advisory Board (composed of senior investigators within and outside of psychiatry research which will conduct assessments of Center progress and suggest refinements) as well as convene regular meetings of the Center’s Faculty Panel, and Stakeholder Committees. Taken together, the Core activities are designed to ensure that the LEAP Center becomes a unified whole that is greater than the sum of its parts.