Project-008
Project-008
批准号:
10376317
负责人:
Randall J Urban
金额:
$28.03万
依托单位国家:
美国
项目类别:
财政年份:
2015
资助国家:
美国
项目状态:
未结题
起止时间:
2015-08-18 至 2025-03-31
关键词:
AddressAgeCharacteristicsClinical ResearchClinical and Translational Science AwardsCommunitiesDataDiverse WorkforceEducational CurriculumEffectivenessGenderHandHealthHomeIndividualInstitutesLeadershipLearningLongevityMedicalMethodsModelingMulti-Institutional Clinical TrialNational Center for Advancing Translational SciencesParticipantPhaseResearchResearch PersonnelResearch SupportResource SharingResourcesScienceSpecial PopulationTechnologyTestingTexasTrainingTraining and InfrastructureTranslation ProcessTranslational ResearchUniversitiesWorkanalytical toolbasecommunity engagementdesigneffective interventionexperiencehealth goalsimprovedinformatics infrastructureinnovationinter-institutionalinteroperabilityknowledge basemeetingsmulti-site trialmultidisciplinarynoveloperationprogramsracial and ethnicscience educationskillstranslational pipeline
中文摘要
德克萨斯大学医学分支(UTMB)自2009年以来一直作为CTSA中心参与。学术之家
我们的CTSA,翻译科学研究所(ITS),汇集了多学科的翻译
团队(MTT)和必要的资源,以加速发现更好的健康为个人,
社区.在我们现有优势的基础上,CTSA的举措改变了UTMB的学习和研究
文化的一个拥抱多学科翻译团队(MTT)的方法,以解决重大
健康问题我们开发了新颖的教育课程,重要的临床研究项目,
多中心临床试验的特殊人群,并在德克萨斯州地区CTSA联盟中提供领导
(国家)和国家。UTMB的CTSA中心通过生成,测试和
通过利益相关者的参与传播综合团队科学、教育和最佳实践
阶段通过使用创新记分卡的持续改进模型进行管理,我们将解决六个问题
具体目标是:1)扩大协作团队的知识基础和实践,以推进行为
通过基于团队的创新进行转化研究。在我们团队科学领导力的基础上,我们将测试,
学习和传播多机构合作,以提高质量,效率,有效性和多样性
临床和转化研究。2)让地方、区域和国家利益相关者参与进来,
有效地满足他们的需求。我们将利用我们的关系,扩大机构间的伙伴关系,
与利益攸关方合作,传播科学成果,推动社区参与。第三章
充分利用跨翻译范围的协调大型数据平台的潜力,以改进研究
提高效率,开发技术以支持研究团队,并与研究人员共享资源。
CTSA网络。我们的目标是加强我们的信息学基础设施和培训,
CTSA网络互操作性将现有的和新的分析工具交到用户手中。4)促进
包括特殊人群在内的整个生命周期的临床和转化研究。我们将扩大我们的
在特殊人群中进行多中心试验的显著优势,以积极参与NCATS试验创新
来自UTMB的新试验网络。5)改善对多样化劳动力的真实技能培训
需要推进临床和转化研究的各个阶段。我们的综合U,K和T计划将
包括具有不同专业和教育经验以及不同年龄、性别、种族
和民族特征。6)制定和传播经改进的翻译方法和程序,
发现改善健康。我们将采用持续改进的方法来了解障碍,
有效的干预措施,并传播转化科学和操作的改进。
英文摘要
The University of Texas Medical Branch (UTMB) has participated as a CTSA hub since 2009. The academic home
of our CTSA, the Institute for Translational Sciences (ITS), has brought together multidisciplinary translational
teams (MTTs) and the resources necessary to accelerate discoveries toward better health for individuals and
communities. Building on our existing strengths, CTSA initiatives have transformed UTMB’s learning and research
culture to one that embraces multidisciplinary translational team (MTT) approaches to addressing significant
health problems. We have developed novel educational curricula, significant clinical research programs in
special populations with multisite clinical trials, and provided leadership in the Texas Regional CTSA consortium
(TRCC) and nationally. UTMB’s CTSA hub supports the health goals of the nation by generating, testing and
disseminating integrative team science, education and best practices through stakeholder involvement at all
stages. Managed by a continuous improvement model using an Innovation Scorecard, we will address six
specific aims, to: 1) Expand the knowledge base and practice of collaborative teams to advance the conduct
of translational research through team-based innovation. Building on our team science leadership, we will test,
learn, and disseminate multi-institutional teaming to enhance the quality, efficiency, effectiveness, and diversity
of clinical and translational research. 2) Engage local, regional, and national stakeholders to make research more
effective at meeting their needs. We will build upon our relationships to extend inter-institutional partnerships, and
to work with stakeholders to disseminate scientific findings and advance the field of community engagement. 3)
Harness the potential of harmonized large data platforms across the translational spectrum to improve research
efficiency, develop technologies to support research teams, and share resources with researchers across the
CTSA network. Our aims are designed to enhance our informatics infrastructure and training with regional and
CTSA network interoperability putting existing and novel analytics tools into the hands of users. 4) Promote
clinical and translational research across the lifespan including special populations. We will expand upon our
significant strengths in multi-site trials in special populations to proactively engage the NCATS Trial Innovation
Network for new trials originating from UTMB. 5) Improve training for a diverse workforce in the authentic skills
needed to advance all phases of clinical and translational research. Our integrated U, K, and T programs will
include participants with diverse professional and educational experience, as well as diverse age, gender, racial,
and ethnic characteristics. 6) Develop and disseminate improved methods and processes for translation from
discovery to improved health. We will apply a continuous improvement approach to understand barriers, develop
effective interventions, and disseminate improvements in translational science and operations.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
UTMB Clinical and Translational Science Award
-
批准号:10376310
-
项目类别:
-
资助金额:$428.64万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
UTMB Clinical and Translational Science Award
-
批准号:10568556
-
项目类别:
-
资助金额:$7.98万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-002
-
批准号:10611943
-
项目类别:
-
资助金额:$56.85万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-006
-
批准号:10611952
-
项目类别:
-
资助金额:$44.55万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-004
-
批准号:10376313
-
项目类别:
-
资助金额:$51.62万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-006
-
批准号:10376315
-
项目类别:
-
资助金额:$68.82万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
UTMB Clinical and Translational Science Award
-
批准号:10259247
-
项目类别:
-
资助金额:$6.15万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
UTMB Clinical and Translational Science Award
-
批准号:10611942
-
项目类别:
-
资助金额:$277.46万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-004
-
批准号:10611948
-
项目类别:
-
资助金额:$33.41万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-007
-
批准号:10611954
-
项目类别:
-
资助金额:$32.82万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-008
-
批准号:10611956
-
项目类别:
-
资助金额:$18.14万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
UTMB Clinical and Translational Science Award
-
批准号:10295495
-
项目类别:
-
资助金额:$21.58万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-002
-
批准号:10376311
-
项目类别:
-
资助金额:$87.83万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-003
-
批准号:10611947
-
项目类别:
-
资助金额:$61.75万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-005
-
批准号:10611950
-
项目类别:
-
资助金额:$29.94万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
UTMB Clinical and Translational Science Award
-
批准号:10101777
-
项目类别:
-
资助金额:$410.2万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-007
-
批准号:10376316
-
项目类别:
-
资助金额:$50.69万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-005
-
批准号:10376314
-
项目类别:
-
资助金额:$46.26万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Project-003
-
批准号:10376312
-
项目类别:
-
资助金额:$95.39万
-
财政年份:2015
-
负责人:Randall J Urban
-
依托单位:
Limited Competition: National Biocontainment Laboratories (NBLs) Operations Support (UC7)
-
批准号:9927560
-
项目类别:
-
资助金额:$1150.0万
-
财政年份:2011
-
负责人:Randall J Urban
-
依托单位:
国内基金
海外基金
登录
查看更多内容
补阳还五汤通过AGE-RAGE通路调控脓毒症免疫失衡的机制与转化研究
-
批准号:JCZRLH202601523
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2026
-
负责人:
-
依托单位:
靶向递送一氧化碳调控AGE-RAGE级联反应促进糖尿病创面愈合研究
-
批准号:JCZRQN202500010
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:
-
依托单位:
对香豆酸抑制AGE-RAGE-Ang-1通路改善海马血管生成障碍发挥抗阿尔兹海默病作用
-
批准号:2025JJ70209
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2025
-
负责人:雷芬芳
-
依托单位:
AGE-RAGE通路调控慢性胰腺炎纤维化进程的作用及分子机制
-
批准号:--
-
项目类别:面上项目
-
资助金额:--
-
批准年份:2024
-
负责人:万荣
-
依托单位:
甜茶抑制AGE-RAGE通路增强突触可塑性改善小鼠抑郁样行为
-
批准号:2023JJ50274
-
项目类别:省市级项目
-
资助金额:--
-
批准年份:2023
-
负责人:贺志明
-
依托单位:
蒙药额尔敦-乌日勒基础方调控AGE-RAGE信号通路改善术后认知功能障碍研究
-
批准号:--
-
项目类别:地区科学基金项目
-
资助金额:33万元
-
批准年份:2022
-
负责人:都义日
-
依托单位:
补肾健脾祛瘀方调控AGE/RAGE信号通路在再生障碍性贫血骨髓间充质干细胞功能受损的作用与机制研究
-
批准号:--
-
项目类别:面上项目
-
资助金额:52万元
-
批准年份:2022
-
负责人:叶宝东
-
依托单位:
LncRNA GAS5在2型糖尿病动脉粥样硬化中对AGE-RAGE 信号通路上相关基因的调控作用及机制研究
-
批准号:
-
项目类别:省市级项目
-
资助金额:10.0万元
-
批准年份:2022
-
负责人:于海兵
-
依托单位:
围绕GLP1-Arginine-AGE/RAGE轴构建探针组学方法探索大柴胡汤异病同治的效应机制
-
批准号:81973577
-
项目类别:面上项目
-
资助金额:55.0万元
-
批准年份:2019
-
负责人:辛贵忠
-
依托单位:
AGE/RAGE通路microRNA编码基因多态性与2型糖尿病并发冠心病的关联研究
-
批准号:81602908
-
项目类别:青年科学基金项目
-
资助金额:18.0万元
-
批准年份:2016
-
负责人:刘括
-
依托单位: