Project-004

项目-004

基本信息

  • 批准号:
    10376313
  • 负责人:
  • 金额:
    $ 51.62万
  • 依托单位:
  • 依托单位国家:
    美国
  • 项目类别:
  • 财政年份:
    2015
  • 资助国家:
    美国
  • 起止时间:
    2015-08-18 至 2025-03-31
  • 项目状态:
    未结题

项目摘要

The lack of sufficient high-quality, reproducible data across clinical and translational research is creating a major obstacle for the effective translation of basic research to improve health outcomes. This complex problem includes inadequate study design, inefficient dissemination of research findings, inadequate patient recruitment, suboptimal use of electronic health practices, and poor documentation practices. About two thirds of typical errors are related to problems in the experimental design and performance. Proper study design involves a comprehensive approach to planning, performance, documentation, analysis, and publication. The research methods experts at UTMB play a critical role in comprehensive study design and statistical analysis, as well as interpretation and dissemination of high-quality, ethical clinical and translational research. We have experience across the entire translational research continuum, with particular expertise in bioinformatics, patient-centered outcomes research/comparative effectiveness research, large database analysis, clinical trials, data mining, and network analysis. In this research methods component we will address the major issues in clinical and translational studies making our CTSA more effective, efficient, and making our studies easily disseminated to improve health across the country. To accomplish this, we will provide resources to our investigators in the areas Biostatistics, Epidemiology and Research Design. The Biostatistics Epidemiology and Research Design group will provide researchers easy access to biostatistical education/training, research design consultation, and innovative tools and methods to enhance the quality, rigor and efficiency of clinical and translational. The Office of Clinical Research will provide investigators and study teams with focused regulatory knowledge and clinical trial management support. We will support investigators with innovative tools such as developing apps to assess data quality and data mining methods to assess pharmacotherapy-associated toxicities. We will also apply innovative techniques to enhance trial design and to analyze the results of comparative effectiveness research. In addition, we will develop a process to obtain electronic consent.Our Research Methods component will enhance innovation, access and quality of clinical and translational research at UTMB. This is accomplished with tight integration between research methods, hub capacity, and informatics. Our research methods program encompasses two integrated modules. The Biostatistics, Epidemiology and Research Design (BERD) team is an essential component of the translational research mission at UTMB, providing: team-based collaboration and consultation on research design and biostatistics; continuous education, mentoring and training to students and faculty; and strong support to the informatics core. BERD will continue to play a critical role in developing innovative research methods at UTMB, with particular emphasis on enhanced clinical trials, advanced comparative effectiveness research methods, and novel data management tools. The Office of Clinical Research (OCR) was established in June 2011 as a joint initiative between Research Services and the CTSA. It is a multidisciplinary service organization, staffed by a team experienced in sponsored clinical research, that supports faculty with sponsored clinical trials and investigator-initiated clinical research projects. Guided by the continuous improvement model of our Innovation Score Card, the integrated modules of our Research Methods component will address the following Specific Aims:
临床和转化研究中缺乏足够的高质量、可重复的数据,这正在造成一个严重的问题

项目成果

期刊论文数量(0)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)

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Randall J Urban其他文献

Anterior hypopituitarism following traumatic brain injury
脑外伤后垂体前叶功能低下
  • DOI:
  • 发表时间:
    2005
  • 期刊:
  • 影响因子:
    1.9
  • 作者:
    Randall J Urban;P. Harris;B. Masel
  • 通讯作者:
    B. Masel

Randall J Urban的其他文献

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{{ truncateString('Randall J Urban', 18)}}的其他基金

UTMB Clinical and Translational Science Award
UTMB 临床和转化科学奖
  • 批准号:
    10376310
  • 财政年份:
    2015
  • 资助金额:
    $ 51.62万
  • 项目类别:
UTMB Clinical and Translational Science Award
UTMB 临床和转化科学奖
  • 批准号:
    10568556
  • 财政年份:
    2015
  • 资助金额:
    $ 51.62万
  • 项目类别:
Project-002
项目-002
  • 批准号:
    10611943
  • 财政年份:
    2015
  • 资助金额:
    $ 51.62万
  • 项目类别:
Project-006
项目-006
  • 批准号:
    10611952
  • 财政年份:
    2015
  • 资助金额:
    $ 51.62万
  • 项目类别:
Project-006
项目-006
  • 批准号:
    10376315
  • 财政年份:
    2015
  • 资助金额:
    $ 51.62万
  • 项目类别:
UTMB Clinical and Translational Science Award
UTMB 临床和转化科学奖
  • 批准号:
    10259247
  • 财政年份:
    2015
  • 资助金额:
    $ 51.62万
  • 项目类别:
UTMB Clinical and Translational Science Award
UTMB 临床和转化科学奖
  • 批准号:
    10611942
  • 财政年份:
    2015
  • 资助金额:
    $ 51.62万
  • 项目类别:
Project-004
项目-004
  • 批准号:
    10611948
  • 财政年份:
    2015
  • 资助金额:
    $ 51.62万
  • 项目类别:
Project-007
项目-007
  • 批准号:
    10611954
  • 财政年份:
    2015
  • 资助金额:
    $ 51.62万
  • 项目类别:
Project-008
项目-008
  • 批准号:
    10611956
  • 财政年份:
    2015
  • 资助金额:
    $ 51.62万
  • 项目类别:

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