Project-006

项目-006

• 批准号: 10611952
• 负责人: Randall J Urban
• 金额: $ 44.55万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-08-18 至 2025-03-31
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10611952
• 关键词: Area; Clinical Data; Clinical Research; Clinical Trials; Clinical and Translational Science Awards; Collaborations; Computer software; Development; Effectiveness; Environment; Health; Improve Access; Informatics; Link; Measures; Methodology; Multi-Institutional Clinical Trial; Patient Recruitments; Regulation; Reporting; Research Infrastructure; Research Personnel; Resources; Science; Site; Training; Training Programs; Work; clinical center; feasibility trial; improved; informatics infrastructure; innovation; interoperability; novel; programs; recruit; tool; web site

The main functions of the Network Capacity component of the UTMB CTSA Hub are to support networkwide studies through our Trial Innovation Network (TIN) Hub Liaison Team and to link our hub with the CTSA Program Central Resources, including the Center for Leading Innovation and Collaboration (CLIC) and the Clinical Data to Health Coordinating Center (CD2H-CC). We will provide a nurturing environment to conduct high-quality, efficient, and regulation-compliant multi-site clinical trials in our areas of unique strength. We will continue to expand and enhance the clinical research and informatics infrastructure to provide more opportunities for our investigators to participate in TIN multi-site clinical trials and CLIC and CD2H-CC initiatives. We will also support the local development of multi-site studies to propose for dissemination by the TIN and will disseminate our Informatics discoveries and our innovative Team Science training programs nation-wide. We have strengthened and streamlined our clinical research infrastructure. We have integrated the Hub Liaison Team with the Office of Clinical Research, the single point of contact for all clinical studies. We have been working with our Informatics core to develop novel tools for clinical trial feasibility, patient recruitment, clinical data extraction and reporting, and multi-hub software interoperability. We have worked with Trials Today to establish a searchable customized UTMB trials website. The Hub Liaison Team will leverage the OCR and the informatics advancements to develop high-quality multi-site clinical trials with high recruitment yields at UTMB through its interactions with the TIN. The Network Capacity Specific Aims are: Aim 1. Optimize the UTMB Hub Liaison Team to improve access, rapidly respond to, and support CTSA Network TIN studies. Aim 2. Support and link the CTSA Program Central Resources with the UTMB Hub. Aim 3. Disseminate Team Science training to the CTSA Network. Effectiveness of the Network Capacity activities will be measured using common metrics as well as metrics locally developed using our continuous improvement methodology

UTMB CTSA 中心的网络容量组件的主要功能是支持全网 通过我们的试验创新网络 (TIN) 中心联络团队进行研究，并将我们的中心与 CTSA 连接起来 计划中央资源，包括领先创新与协作中心 (CLIC) 和 临床数据提交给健康协调中心 (CD2H-CC)。我们将提供一个培育环境来开展 在我们独特的优势领域进行高质量、高效且符合法规的多中心临床试验。我们 将继续扩大和加强临床研究和信息学基础设施，以提供更多 我们的研究人员有机会参与 TIN 多中心临床试验以及 CLIC 和 CD2H-CC 倡议。我们还将支持当地开展多地点研究，以建议通过 TIN 并将传播我们的信息学发现和创新的团队科学培训计划 全国。我们加强并简化了我们的临床研究基础设施。我们已经集成了 中心联络团队与临床研究办公室，是所有临床研究的单一联络点。 我们一直在与我们的信息学核心合作，开发用于临床试验可行性、患者 招募、临床数据提取和报告以及多中心软件互操作性。我们已经工作过 与 Trials Today 合作建立一个可搜索的定制 UTMB 试验网站。中心联络小组将 利用 OCR 和信息学进步来开发高质量的多中心临床试验，具有高 UTMB 通过与 TIN 的互动来提高招聘效率。网络容量的具体目标是： 目标 1.优化UTMB枢纽联络团队，改善准入，快速响应，支持CTSA 网络 TIN 研究。目标 2. 支持 CTSA 计划中央资源并将其与 UTMB 联系起来 中心。目标 3. 向 CTSA 网络传播团队科学培训。网络的有效性 将使用通用指标以及使用我们的本地开发的指标来衡量容量活动 持续改进方法论