Developmental Core

发展核心

• 批准号: 10384036
• 负责人: Christopher C. Beyrer
• 金额: $ 125.36万
• 依托单位: JOHNS HOPKINS UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-09-23 至 2022-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10384036
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Address; Area; Award; Baltimore; Behavioral; Biological Assay; Cities; Clinical; Clinical Research; Collaborations; Communities; Continuity of Patient Care; Data; Developing Countries; Development; Diagnosis; Discipline; Education and Outreach; Environment; Epidemic; Epidemiology; Esapent; Extramural Activities; Faculty; Fostering; Funding; Future; Generations; Goals; Grant; HIV; Health Occupations; Heart; Individual; Institution; Intervention; Intervention Studies; Investments; Laboratories; Lead; Leadership; Mentors; Mentorship; Minority Groups; Mission; NCI Scholars Program; Participant; Performance; Pilot Projects; Population; Productivity; Public Health Nursing; Reduce health disparities; Research; Research Activity; Research Design; Research Methodology; Research Personnel; Research Support; Research Training; Resources; Schools; Science; Services; Social Justice; Specimen; Student recruitment; Students; Time; Training; Underrepresented Minority; Underrepresented Populations; United States National Institutes of Health; Universities; career; collaboratory; combat; community based evaluation; community setting; design; experience; graduate student; health disparity; innovation; interdisciplinary collaboration; medical schools; medical specialties; member; minority investigator; multidisciplinary; next generation; outreach; programs; recruit; research study; response; student participation; synergism; undergraduate student; virtual; working group

This is a competing renewal for the new Johns Hopkins University CFAR, initially funded in 2012. The new CFAR had a complete change in leadership, a major reorganization, a number of new and highly innovative approaches, and the enthusiastic and vigorous participation and support of the entire JHU HIV research community and the institution's leaders, who have contributed $2.25 million of additional support to fund additional developmental awards, student engagement, and outreach activities. For the past 4 years the CFAR has reinvigorated the HIV community at JHU, built thriving platforms through which interdisciplinary collaboration occurs, engaged new and junior investigators in cutting-edge research activities, provided vitally needed developmental resources for conducting pilot studies that lead to extramural funding, and contributed to the recruitment of new faculty, particularly 6 members of underrepresented minority groups. The CFAR has served over 373 HIV investigators, >130 NIH grants, and provided mentoring and assistance to 212 early stage investigators. Developmental Awards to early stage investigators or those new to HIV research have resulted in $57 million in new extramural awards, and our Internal Scientific Reviews of NIH applications have contributed to the funding of 14 new R01 or similar grants. The overall goal of this competing renewal application is to continue and enhance the ability of the Johns Hopkins University CFAR to nurture and support high-impact HIV research and researchers across a broad range of disciplines and specialties in the multiple divisions of this major research university. Our specific aims are 1) to enhance the integration and productivity of HIV/AIDS research by promoting inter-disciplinary innovation and collaboration; 2) to provide mentoring, support, and pilot funding for the next generation of HIV/AIDS researchers, with a commitment to recruiting researchers from underrepresented minority groups; 3) to support HIV/AIDS researchers with direct services to assist with recruitment of clinical research participants, performance of laboratory assays, design and analysis of research studies, and training in research methodologies; and 4) to mobilize and coordinate capacity from across JHU to combat the HIV epidemic in Baltimore through engagement, training, outreach, and evaluation of community-based intervention studies. The CFAR has 6 Cores and 3 Scientific Working Groups that provide services and support innovation in high-priority HIV research. The Baltimore HIV Collaboratory, and its Plan Baltimore 2020 project coordinate the JHU response to the local epidemic, orchestrating HIV research and outreach activities, and expanding the pipeline of future HIV researchers through the Baltimore HIV Scholars Program and Generation Tomorrow, initiatives aimed at students. The Provost and Deans of the 3 health professions schools at JHU have committed institutional funds of $2.7 million to support pilot awards, student recruitment, and Baltimore engagement. The CFAR will continue to have a galvanizing and transformative impact on HIV/AIDS research at JHU and we are delighted to submit this renewal application.

这是新的约翰霍普金斯大学CFAR的竞争性更新，最初于2012年资助。新 CFAR在领导层进行了彻底的变革，进行了重大的重组， 方法，以及整个JHU HIV研究的热情和积极参与和支持 社区和该机构的领导人，谁贡献了225万美元的额外支持，以基金 额外的发展奖励，学生参与和推广活动。在过去的四年里， CFAR重振了JHU的艾滋病毒社区，建立了蓬勃发展的平台，通过这些平台，跨学科 合作发生，从事新的和初级研究人员在尖端的研究活动，提供至关重要的 需要发展资源进行试点研究，导致校外资金，并作出了贡献， 招聘新的教师，特别是6名代表不足的少数群体成员。CFAR已 为超过373名艾滋病毒调查人员提供了服务，获得了超过130项NIH赠款，并为212名早期艾滋病毒感染者提供了指导和援助。 舞台调查员早期研究人员或艾滋病毒研究新手的发展奖 导致了5700万美元的新的校外奖励，我们对NIH申请的内部科学审查已经 为14个新的R 01或类似赠款提供了资金。这次竞争性更新的总体目标是 应用是继续和提高约翰霍普金斯大学CFAR的能力，培养和支持 高影响力的艾滋病毒研究和研究人员在广泛的学科和专业的多个 这所主要研究型大学的各个部门。我们的具体目标是：1）提高集成度和生产力 通过促进跨学科的创新和合作，促进艾滋病毒/艾滋病研究的发展; 2）提供指导， 为下一代艾滋病毒/艾滋病研究人员提供支持和试点资金，并承诺招募 来自代表性不足的少数群体的研究人员; 3）支持艾滋病毒/艾滋病研究人员， 协助招募临床研究参与者，进行实验室检测，设计和分析 （a）加强研究和研究方法的培训;（b）调动和协调 通过参与、培训、外展和评估，在巴尔的摩抗击艾滋病毒流行 基于社区的干预研究。CFAR有6个核心和3个科学工作组， 服务，并支持高优先艾滋病毒研究的创新。巴尔的摩艾滋病毒合作实验室及其计划 巴尔的摩2020项目协调JHU对当地流行病的反应，协调艾滋病毒研究， 外展活动，并通过巴尔的摩艾滋病毒学者扩大未来艾滋病毒研究人员的管道 计划和明天的一代，针对学生的倡议。3健康的教务长和院长 JHU的专业学校已承诺提供270万美元的机构资金，以支持试点奖励，学生 招募和巴尔的摩的参与。CFAR将继续发挥激励和变革作用， 影响艾滋病毒/艾滋病研究在JHU，我们很高兴提交此更新申请。