Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program

描述(由申请人提供)：本提案是一项新的为期5年的国家研究服务奖机构研究补助金的申请，以支持约翰霍普金斯大学彭博公共卫生学院(BSPH)和约翰霍普金斯大学医学院(SOM)在艾滋病毒流行病学和预防科学方面的培训计划，名为“约翰霍普金斯大学艾滋病毒流行病学和预防科学培训计划”。提议的计划将由公共卫生硕士克里斯·拜雷尔博士和公共卫生公共卫生硕士副主任Shruti Mehta博士领导。我们请求为4名博士后和2名博士后学员提供支持。该计划的任务是培养博士后学生和博士后研究员，在三个培训轨道上成为艾滋病毒/艾滋病研究的前沿领导者：艾滋病毒流行病学研究方法和翻译科学，其中包括以下方面的培训：(1)人口和研究设计，包括识别、招募和保留与艾滋病毒研究和全球艾滋病毒流行病学队列研究相关的人口；(2)艾滋病毒人口中的衡量问题，包括监测、艾滋病毒流行率和发病率的创新方法，以及新的基于人口的疾病负担衡量；(3)推理技术，包括用于因果推理和数学建模的现代分析方法；和(4)综合研究成果并将其转化为公共卫生实践，包括系统审查/荟萃分析和实施科学。艾滋病毒临床流行病学和实验室科学，包括(1)与艾滋病毒有关的主要联合感染和共病的流行病学，(2)遗传、病毒学、免疫学和临床因素谱的测量。艾滋病毒预防科学包括如何通过以下方面的培训预防和减轻艾滋病毒负担：(1)艾滋病毒获取和传播的行为科学方面，(2)艾滋病毒生物医学和行为预防试验的设计和分析，包括作为预防研究的治疗(TasP)，以及(3)超越个人行为变化的艾滋病毒预防和控制的基于社区和人口层面的方法。该计划的目标是创造一个丰富和互动的受训人员环境，并通过约翰·霍普金斯大学BSPH和SOM的观察性、临床和预防科学家进行的格外创新、富有成效和协作的艾滋病毒研究来加强。

DESCRIPTION (provided by applicant): This proposal is an application for a new 5-year National Research Service Award Institutional Research Grant to support a training program in HIV Epidemiology and Prevention Sciences at the Johns Hopkins Bloomberg School of Public Health (BSPH) and the Johns Hopkins School of Medicine (SOM), entitled the "Johns Hopkins HIV Epidemiology and Prevention Sciences Training Program." The proposed program would be led by Director Chris Beyrer MD, MPH, and Deputy Director Shruti Mehta PhD, MPH. We are requesting support for 4 pre- and 2 post-doctoral trainees. The program mission is to train pre-doctoral students and post- doctoral fellows to become leaders at the forefront of research in HIV/AIDS with advanced competencies and state-of-the-art skills in three training tracks: HIV Epidemiology Research Methods and Translational Sciences which includes training in (1) Populations and Study Designs, including identifying, recruiting, and retaining populations relevant for HIV research and global HIV epidemiological cohort studies; (2) Measurement issues in HIV populations, including innovative methods for surveillance, estimation of HIV prevalence and incidence, and novel population-based measures of disease burden; (3) Inference techniques, including modern analytical methods for causal inference and mathematical modeling; and (4) Synthesis and Translation of research findings to public health practice, including systematic reviews/meta-analyses and implementation science. HIV Clinical Epidemiology and Laboratory Sciences including training in (1) the epidemiology of major co-infections and co-morbidities associated with HIV, (2) Measurement of the spectrum of genetic, virologic, immunologic, and clinical factors. HIV Prevention Sciences including how to prevent and reduce the burden of HIV through training in (1) Behavioral Science aspects of HIV acquisition and transmission, (2) Design and Analysis of HIV biomedical and behavioral prevention trials, including treatment as prevention research (TasP), and (3) Community-based and Population-level approaches to HIV prevention and control beyond individual behavior change. The program goal is to create a rich and interactive trainee environment augmented by the exceptionally innovative, productive, and collaborative HIV research conducted by observational, clinical, and prevention scientists throughout Johns Hopkins BSPH and SOM.