San Diego Digestive Diseases Research Center

总结 圣地亚哥消化系统疾病研究中心成立于33个杰出的研究基地， 研究人员目前的消化系统疾病相关资金为15，689，402美元，年度直接费用总额为 其中5，711，412美元（36.4%）来自NIDDK。该中心的总体使命是支持基本的、翻译性的 和临床研究，这将导致改善治疗和预防炎症性疾病的 消化系统该中心的主要目标是为一个国家的研究实验室提供服务。 圣地亚哥地区四个相邻研究机构的联盟，将促进研究生产力， 新的研究方向，并鼓励富有成效的合作。圣地亚哥的另一个主要目标 消化系统疾病研究中心通过试点/可行性研究加强新的消化系统疾病研究 丰富的计划。该中心支持三个相互关联的生物医学研究核心， 旨在提高中心成员的研究潜力和生产力。人类翻译 核心建立在临床和转化研究的现有专业知识基础上， 标本和利用独特的现有库的炎症性肠病和肝病。的 临床前模型核心促进和协助表征和理解胃肠道和肝脏 使用鼠模型。微生物学和功能基因组学核心提供尖端和 在微生物组学和功能基因组学方面以成本效益高的方式获得测序技术。 此外，一个行政核心在行政上支持中心，并协调试点/可行性 丰富的计划。这些核心共同提供高质量和最先进的研究资源 提高成员的协作积极性和有效性，促进青少年的发展 investigators.结合试点/可行性和丰富计划，圣地亚哥消化系统疾病 研究中心将补充一个强大的科学家骨干集中在一系列重要的炎症 胃肠道和肝脏疾病。通过创造一个独特的环境来培养新的研究 想法和互动，圣地亚哥消化疾病研究中心提供了一个独特的机会， 整合临床和实验室研究，以促进对消化系统疾病的基本认识，并提高 这些疾病患者的健康和护理。

Summary The San Diego Digestive Diseases Research Center is founded on a research base of 33 outstanding investigators with current digestive diseases-relevant funding of $15,689,402 in total annual direct costs, of which $5,711,412 (36.4%) are from NIDDK. The overall mission of the Center is to support basic, translational and clinical research that will lead to improved treatment and prevention of inflammatory diseases of the digestive system. The primary goal of the Center is to provide services to the research laboratories of a consortium of four adjacent research institutions in the San Diego area that will foster research productivity and new research directions, and encourage productive collaborations. Another major goal of the San Diego Digestive Diseases Research Center is to enhance new digestive diseases research through Pilot/Feasibility and Enrichment programs. The Center supports three interrelated Biomedical Research Cores that are designed to enhance the research potential and productivity of the Center members. The Human Translational Core builds upon existing expertise in clinical and translational research to provide access to human specimens and leverages unique existing repositories of inflammatory bowel disease and liver diseases. The Preclinical Models Core facilitates and assists in characterizing and understanding of gastrointestinal and liver diseases using murine models. The Microbiomics and Functional Genomics Core provides cutting-edge and cost-effective access to sequencing-based technologies in microbiomics and functional genomics. Furthermore, an Administrative Core supports the Center administratively and coordinates the Pilot/Feasibility and Enrichment programs. Together, these Cores provide high-quality and state-of-the-art research resources to increase collaborative activity and effectiveness of the members, and promote the development of junior investigators. Combined with the Pilot/Feasibility and Enrichment programs, the San Diego Digestive Diseases Research Center will complement a strong cadre of scientists focused on a range of important inflammatory diseases of the gastrointestinal tract and liver. By creating a unique environment to nurture novel research ideas and interactions, the San Diego Digestive Diseases Research Center presents a unique opportunity to integrate clinical and bench research to advance the basic understanding of digestive diseases, and enhance the health and care of patients suffering from those diseases.